Mankhwalawa "Sporagal": malangizo ogwiritsira ntchito, kufanana ndi ndemanga

Kodi ndizitenga bwanji mankhwalawa "Sporagal"? Malangizo ogwiritsira ntchito mankhwalawa adzakambidwa mochedwa. Komanso, mudzapeza ngati pali zofanana ndi mankhwalawa, kuchuluka kwa ndalama, zomwe odwala akunena zokhudzana ndi izi, cholinga chake, ndi zina zotero.

Mapangidwe, maonekedwe, kapangidwe ka mankhwala osokoneza bongo

Mankhwalawa "Sporagal" amabwera ngati mawonekedwe a capsules. Chofunika chake chachikulu ndicho itraconazole. Zophatikizidwepo ndi polyethylene glycol 20,000, sucrose, hydroxypropylmethylcellulose ndi acrylate copolymer.

Pogwiritsa ntchito chipolopolocho, chimakhala ndi gelatin, titaniyamu ya dioxide ndi indigotine.

Kodi ndi mankhwala otani omwe mankhwala a "Sporagal" adagulitsidwa? Malangizo ogwiritsira ntchito chida ichi aikidwa m'kabokosibokosi. Limakhalanso ndi makapulisi owopsa a gelatin a mtundu wa buluu (mkati mwake), mkati momwe muli zofiira zamtundu wa chikasu.

Mankhwala osokoneza bongo

Kodi Sporagal amapiritsila ntchito bwanji? Malinga ndi malangizo ophatikizidwa, mankhwalawa ndi ochotsera triazole. Ili ndi ntchito yayikulu yolimbana ndi bowa.

Kuloledwa kwa mankhwala kumathandiza kuchepetsa kapangidwe ka tizilombo ka ergosterol, kupangitsa kuti tisagwiritsidwe ntchito.

Akatswiri amanena kuti itraconazole imalepheretsa kukula ndi kuberekana kwa mitundu yambiri ya bowa.

Pharmacokinetics ya wothandizira

Mankhwalawa "Sporagal", omwe amafanana nawo omwe atchulidwa pansipa, amadziwika mwamsanga m'magazi. Mbali yaikulu ya itraconazole mu thupi la munthu imasungidwa patatha maola atatu. Zomwe zimapezeka ndi 55 peresenti (chiwerengerochi chimatchulidwa poyesa kapsules mwamsanga mutatha kudya chakudya chambiri komanso chapamwamba).

Itraconazole imagawidwa ku ziwalo zosiyana ndi matenda a thupi. Zomwe zili m'kati mwa mafupa, impso, chiwindi, mapapo, zifuwa, mimba ndi ntchentche ndi zazikulu katatu kuposa magazi.

Mankhwala amatsitsimutso pachiwindi ndi kugawidwa kwa mankhwala ambiri. Komabe, hydroxyitraconazole yokha ndi yomwe imatulutsa mphamvu yogonjetsa.

Pafupifupi 34 peresenti ya mankhwala yogwiritsidwa ntchito amakhala osakanizika pamodzi ndi mkodzo ndi 54% mwa matumbo.

Kwa anthu omwe ali ndi vuto la chiwindi ndi impso, komanso odwala omwe ali ndi matenda osokoneza bongo, mankhwalawa akhoza kuchepa.

Zizindikiro zogwiritsira ntchito makapisozi

Kodi cholinga cha "Sporagal" ndi chiyani? Malangizowo akuti mankhwalawa akukonzedwa kuti azitha kuchiza mavoti omwe anandipweteka ndi tizilombo toyambitsa matenda omwe amamvetsera mankhwalawa:

• Candidiasis vulvovaginal;
• Matenda opatsirana ndi odwala ndi a m'magazi a fungal (monga fungal keratitis, dermatomycosis, pityriasis);
• Chilankhulo ;
• Onychomycosis, zomwe zinakwiyidwa ndi dermatophytes kapena yisiti;
• Matenda opatsirana oopsa, kuphatikizapo cryptococcosis (kwa anthu omwe ali ndi mphamvu yoteteza thupi ku chitetezo cha cryptococcosis ya mitsempha ya mankhwala, mankhwala amaperekedwa kokha ngati palibe mankhwala ochotsera mankhwala), meningitis cryptococcal, systemic aspergillosis, ndi candidiasis;
• Sporotrichosis, paracoccidioidosis, blastomycosis, histoplasmosis, ndi zina zosavuta zowonongeka.

Zotsutsana ndi kugwiritsa ntchito makapisozi

Kodi ndi zotsutsana bwanji ndi kugwiritsa ntchito mankhwala "Sporagal" (mapiritsi)? Malangizo akuti mankhwalawa amaletsedwa kugwiritsa ntchito pamene:

• Hypersensitivity kwa zigawo zazikulu ndi zothandizira za mankhwala
• Kuphatikizana ndi mankhwala monga Eletriptan, blockers a HMG-CoA reductase (mwachitsanzo, Atorvastatin, Lovastatin, Simvastatin), amagwiritsa ntchito mapepala a CYP3A4 (mwachitsanzo, Cizapride, Bepridil, Pimozid , "Dofetilide", "Astemizol", "Quinidine", "Mizolastin"), "Kusamalitsa", "Midazolam", "Triazolam".

Tiyeneranso kukumbukira kuti kugwiritsa ntchito mankhwalawa kumatsutsana ndi anthu omwe ali ndi vuto lolephera kugwira ntchito komanso mtima wosagwira ntchito, makamaka momwemo.

Mankhwalawa "Sporagal": malangizo othandizira

Malinga ndi malangizo, mankhwalawa ayenera kutengedwa pamlomo. Ma Capsules ayenera kudyedwa mwamsanga mutangodya (pofuna kuonetsetsa kuti mukuyamwa bwino) mu mawonekedwe ambiri, popanda kutafuna.

Mlingo wa mankhwalawa umadalira mtundu wa matenda omwe alipo:

• Matenda a m'mimba ndi ophthalmic (mwachitsanzo, pityriasis kapena dermatomycosis) ndi 200 mg kamodzi pa tsiku kwa sabata.
• Zilonda zamatenda m'madera a khungu (manja ndi mapazi) - 200 mg kawiri pa tsiku kwa sabata.
• Candidiasis vulvovaginal - 200 mg kawiri pa tsiku kwa masiku atatu.
• Candidiasis pakamwa - 100 mg kamodzi pa tsiku kwa milungu iwiri. Odwala omwe ali ndi AIDS kapena neutropenia, mlingo wawonjezeka kufika 200 mg kamodzi pa tsiku.
• Fungal keratitis - 200 mg kamodzi pa tsiku kwa masabata atatu.
• Onychomycosis, yomwe imayambitsidwa ndi dermatophytes kapena yisiti bowa, imachiritsidwa ndi maphunziro obwerezabwereza. Njira imodzi yopangira mankhwala imaphatikizapo kutenga makapisozi awiri kawiri pa sabata. Pofuna chithandizo cha misomali pamsana, 2 maphunziro oterewa amapangidwa, ndi miyendo - maphunziro atatu. Kusweka pakati pawo kuyenera kukhala masabata atatu. Zotsatirazi zimawonekera pambuyo pomaliza maphunzirowo (monga zidutswa za msomali zikukula).

Kuchotsa mankhwalawa "Sporagal" ku misomali ndipo khungu limatenga nthawi yaitali kuposa magazi. Pankhani imeneyi, zotsatira zothandizira odwala zimapezeka patangotha masabata atatu chitatha chithandizo cha matendawa ndipo pafupifupi miyezi 9 chithandizo cha onychomycosis.

Njira zogwiritsira ntchito makapisozi mu zotupa zamagetsi

Momwe mungagwiritsire ntchito mankhwalawa? "Sporagal" imayikidwa muzotsatira izi:

• Candidiasis - 100-200 mg kamodzi pa tsiku kwa masabata 5-30.
• Cryptococcosis popanda meningitis - 200 mg patsiku kwa miyezi 3-12. Ndi mlingo wa meningitis umapitsidwanso kawiri.
• Aspergillosis - 200 mg pa tsiku kwa miyezi 3-5.
• Histoplasmosis - 200 mg kawiri pa tsiku kwa miyezi isanu ndi itatu.
• Chromomycosis - 100-200 mg pa tsiku kwa miyezi isanu ndi umodzi.
• Sporotrichosis ndi 100 mg pa tsiku kwa miyezi itatu.
• Paracoccidioidosis - 100 mg pa tsiku kwa miyezi isanu ndi umodzi. Kwa odwala Edzi, mlingo ukhoza kuwonjezeka.
• Blastomycosis - 100-200 mg kawiri pa tsiku kwa miyezi isanu ndi umodzi.

Zotsatira za mankhwala

Kodi pali zotsatira zina pamene mutenga Sporagal? Zolemba kuchokera kwa akatswiri zimafotokoza zotsatirazi:

• Neutropenia, thrombocytopenia, leukopenia;
• Matenda a katemera (kumtunda);
• Hypertriglyceridemia, hypokalemia, hypocalcemia;
• Mutu, paresthesia, phokoso la m'mimba, hypoesthesia, chizungulire;
• Matenda a seramu, edema angioedema, anaphylactoid anaphylactic ndi zovuta;
• Masomphenya obisika, diplopia, kutayika kumva, tinnitus, masomphenya osokonezeka;
• Kulephera kwa mtima, makamaka kupitirira;
• Mpweya wochepa, rhinitis, sinusitis, edema yamapema;
• Kupweteka, kupweteka, kupweteka kwa m'mimba, kupweteka kwa m'mimba, kupweteka kwa chifuwa, kunyowa, dysgeusia, kudzimbidwa, kutsekula kwa chiwindi, kutsegula m'mimba, kuphulika, kuwonjezereka kwa hepatic transaminase;
• Ululu mu ziwalo ndi minofu;
• Urticaria, photosensitivity, leukocytoclastic vasculitis, alopecia, poizoni epidermal necrolysis, pruritus, exfoliative dermatitis, kuthamanga, pustulosis phokoso lalikulu, erythema multiforme;
• Kutsegula m'mimba, kubisala koyambirira, kusokonekera kwa erectile, pollakiuria;
• Kutentha, kutupa.

Malangizo apadera

Kodi wodwalayo ayenera kudziwa chiyani asanatenge Sporagal? Lipoti la ndemanga kuti mankhwala ake yogwira ntchito ali ndi zotsatira zolakwika za inotropic.

Poyambitsa kumwa mankhwalawa, kupwetekedwa mtima kwa mtima kungapangitse, komanso matenda a hepatotoxicity.

Ndi kuchepa kwa acidity, kuyamwa kwa mankhwala kumapweteka kwambiri.

Anthu omwe amagwiritsa ntchito mankhwala ophera tizilombo nthawi yomweyo ayenera kusunga nthawi ya maola awiri pakati pa njira zawo ndi mankhwala omwe akufotokozedwa.

Mankhwalawa "Sporagal" sakuvomerezedwa kwa okalamba odwala.

Pamene zizindikiro za pulogalamu ya mitsempha yowonekera, mankhwalawa ayenera kuchotsedwa.

Kuyamwitsa ndi mimba

Pakati pa mimba, mankhwala amatha kungotchulidwa ndi matenda omwe amayambitsa moyo wa mayi.

Pankhani ya kuyamwitsa, panthaŵiyi, "Sporagal" amaloledwa kugwiritsira ntchito, koma pazinthu zowona.

Mankhwalawa "Sporagal": ofanana ndi mtengo

Mafananidwe odziwika kwambiri a mankhwalawa ndi awa: Itrungar, Sporaksol, Orungal, Eszol, ndi Funit.

Kodi mankhwala okwera "Sporagal" amawononga ndalama zingati? Mtengo wa mankhwalawa umasiyana pakati pa 1100-1200 rubles.

Ndemanga za mankhwala

Malingana ndi ndemanga za iwo omwe adamwa mankhwalawa, zikhoza kuzindikirika kuti zimakhala zogwira mtima mu mitundu yosiyanasiyana ya zilonda za fungal. Kuchokera ku mauthenga osalongosoka ndizotheka kugawana awo omwe akukambidwa, kuti izi zikutanthauza kuti ali ndi mtengo wapatali. Komabe, akatswiri amanena kuti mtengo wa mankhwalawa ndi wolondola chifukwa cha mphamvu zake zothandizira.

Ponena za zolephera za mankhwalawa, odwala nthawi zambiri amasonyeza nthawi yayitali ya chithandizo.