Photodynamic mankhwala mu Oncology: ubwino ndi kuipa

Khansa ali amodzi mwa malo oyamba mwa imfa anthu. M'zaka zaposachedwapa, zikuchepa chinawonjezeka chiwerengero cha khansa kuti amapezeka odwala. Mwatsoka, iwo alibe malamulo alionse pa zaka - matendawa amakhudza akulu onse komanso Sazengereza kuwachitira ndi ana.

Mu nthawi yathu, ntchito zambiri njira zatsopano za mankhwala khansa, mankhwala wandipitirira pankhaniyi kale kutali mtsogolo. Njira amenewa ndi photodynamic mankhwala mu Oncology. Ndi njira imeneyi, tiona pang'ono kwambiri m'nkhaniyi.

Lingaliro la mankhwala photodynamic

Njira imeneyi mankhwala dzina chidule cha PDT ndi chofunikira ake ndi ntchito magulu kuwala ndipo ena mankhwala otchedwa photosensitizers. Atadziŵa kuyatsa mankhwala mankhwala anapeza mu kansa yotupa wayamba deleteriously bwanji maselo ake.

Malinga ndi kutanthauzira kwa zotupa, lokonzekera akhoza kutumikiridwa mu magazi kapena kugwiritsidwa pa khungu. Patapita nthawi yochepa ndi odzipereka zimakhala, ndiyeno chiwembu imatsogoleredwa mtengo uwu wa kuwala.

Tiyeni tione zimene biophysics ake. mankhwala Photodynamic ku Oncology pambuyo mtengo chikugwa kuwala yafupika mogwirizana mankhwala ndi mpweya, ndi chifukwa, maselo a khansa akuphedwa. Ngati mankhwala zimenezi n'kofunika kuchotsa zipangizo ka magazi azilephera chotupa kudya.

Masiteji mankhwala PD

Photodynamic mankhwala mu Oncology zikuphatikizapo zinthu zingapo:

1. Chiyambi kudziwitsa njira m'nsinga.
2. Kudzikundikira mankhwala mu zimakhala anakhudzidwa ndi khansa. Popeza zosiyanasiyana zimakhala ndi mankhwala, stepi ino ndi zina kumatenga masiku angapo. Iwo anali pa nthawi ino, akatswiri anapezeka ndi chotupa pa maziko a mlingo wa ndende ya wozindikiritsa lapansi.
3. Khwelero chotupa walitsa ndi matabwa laser. Ngati khansayo kwambiri kwambiri, matabwa ntchito yobereka chubu LED. Mothandizidwa laser akuyamba anachita poizoni, zomwe zinachititsa khansa maselo kufa, pamene pafupi wathanzi minofu si bwanji.
4. Khwelero kuwola khansa minofu kukonza ndi pansi kusintha. Nthawi ndi pafupifupi mwezi umodzi.

Monga mankhwala ntchito photodynamic ku Oncology

Izi mtundu wa mankhwala ndi kwambiri kusintha khalidwe la moyo wa odwala. PDT alibe nthawi yaitali mawonetseredwe zoipa, koma osati monga chimagwiritsidwa ntchito m'mayiko onse.

Photodynamic Therapy ku Oncology mu Moscow ntchito kuyambira 1998. Pakali pano, ku likulu pali 5 maudindo, omwe achite njirayi. 2 zikwi. Odwala ankapatsidwa mwa njira imeneyi.

The Cancer matenda dispensary №1 wakhala akupangidwa ndi ntchito kukhudzana PDT. Laser walitsa amachitika bwino kumapangitsa kuonjezera akuya malowedwe a kunyezimira kuti masentimita 2.

Ubwino wa njira ya chithandizo

PDT - njira nzeru za kulimbana khansa ndi dongosolo precancerous. Panopa mu magawo oyambirira Oncology ake kugwiritsa ntchito mankhwala monga photodynamic ku Oncology ali ndi mwayi waukulu:

• N'zotheka bwanji maselo a khansa yekha.
• Odwala mosavuta kulekerera ndondomeko pa msinkhu uliwonse.
• Therapy kumakhudza waulemu pa ziwalo ndi zimakhala anakhudzidwa ndi khansa.
• Mu khansa ya ndondomeko khungu amapereka 100% zotsatira ogwira.

• khansa khomo lachiberekero, njira imeneyi ndi yabwino kwambiri, monga timatha inu kupulumutsa dongosolo zoberekera za mkazi.
• Chithandizo angathe kuchitidwa pa outpatient maziko.
• akhoza reapplied ngati n'koyenera.
• Ilibe mavuto zokhudza zonse.
• Pogwiritsa ntchito njirayi, n'zotheka kuchotsa zotupa mu mwakhama kufika malo.
• Pa ndondomeko opirira amadziwa.
• Njira sabweretsa chisoni kotheratu.
• Photodynamic mankhwala mu Oncology angagwiritsidwe ntchito ngati njira osadalira pa chithandizo, ndi mbali ya mankhwala osakaniza.

njira mavuto zowononga pa maselo a khansa, komanso virucidal (wokhoza kuononga anthu papilloma HIV), fungicidal, bactericidal ndi immunomodulatory. Kupezeka kwa oterowo ambiri ubwino kupangitsa otchuka.

zofooka

Kuwonjezera zabwino zambiri, njira ali ndi zovuta zake:

• Therapy okha ku mwayi wa kuwala. Kuti ndi amenable mankhwala ndi gawo limene lili mwachindunji pansi pa khungu. Chifukwa cha ichi, sikutheka ntchito njira kuchotsa maselo a khansa, amene anakakhala pafupifupi onse ziwalo ndipo zimakhala.
• Patapita kanthawi photosensitizers anapitiriza kudziwa kuwala.

Koma zonsezi pamwambapa akusonyezanso kuti photodynamic mankhwala mu Oncology ali ndi zolakwika aang'ono kwambiri.

Zikuonetsa ntchito njira

Tikumbukenso kuti PDT ntchito osati kwa ndiyotani pakuchotsa zotupa khansa, komanso zochizira psoriasis, adzithandize, cutaneous lupus ndi matenda ena. mankhwala Photodynamic ntchito monga kotaya zosiyanasiyana khansa ndi precancer mankhwala. Ndi othandiza matenda diso ndi mavuto dermatological.

Komanso, pogwiritsa ntchito njirayi kupereka chithandizo cha zilonda sanali kuchiritsa ndi zilonda trophic.

Kodi sikusonyeza ndondomeko PDT

Photodynamic mankhwala mu Oncology ali contraindications, koma zazing'ono. Si ikuchitika:

• ngati pali kudwala wa aimpso ndi chiwindi;
• matenda decompensated a dongosolo mtima;
• pa tilinazo kuchuluka kwa mankhwala;
• matenda magazi.

Njira contraindicated pa Kubereka ndi mkaka wa m'mawere.

mankhwala Photodynamic ku Oncology ayenera kugwiritsidwa ntchito atakambilana ndi dokotala, kuti athe kuzindikira contraindications onse alipo.

Kukonzekera ntchito mankhwala

Yokwaniritsira njira imeneyi chithandizo oncologists ntchito mankhwala akhoza kugawidwa m'magulu awiri:

1. sensitizers mbadwo, ndi porphyrins.
2. wachiwiri m'badwo photosensitizers.

Kaya gulu, ku mutu mankhwala amafuna wapadera:

• Iwo ali chuma kuganizira ambiri khansa ndipo zilibe kudutsa mu minofu wathanzi;
• pambuyo ndondomeko mofulumira excreted m'thupi ndipo ali otsika kawopsedwe;
• Zilibe kudziunjikira mu khungu;
• Ndi kugonjetsedwa yosungirako ndi makonzedwe mu m'magazi;
• Iwo ali katundu fulorosenti.

Mwachidule mankhwala PDT

njira A mankhwala photodynamic ku Oncology kawirikawiri amagwiritsidwa ntchito ndi "Photofrin" mankhwala. Iwo adamulowetsa ndi mtundu wofiira. Ndipo ntchito pa matenda a zinthu zotsatirazi:

• Khansa ya m'phuno ndi. Pambuyo ndondomeko wodwala akumva bwino, makamaka chikusonyeza ntchito mankhwala, pamene chotupa kufika kukula pafupifupi kutsekereza m'phuno, ndi laser mankhwala sangathe kulimbana nazo.
• Barrett ndi kum'mero. mankhwala ntchito monga mankhwala ndi njira kupewa chitukuko khansa.
• m'mapapo khansa.

Aminolivulinovaya asidi ntchito mu nkhani ya keratosis senile. Iwo anagwira ntchito mwachindunji pa khungu ndipo adamulowetsa mwa buluu. Ungagwiritsidwe yekha kumaso ndi kumutu.

Pali mankhwala ena, koma ntchito kwambiri kamodzikamodzi.

The ndondomeko mankhwala ntchito "Photofrin"

Mutu medicament ndi m'nsinga jekeseni thupi. Kupeza mkati, iwo amayamba kukhala odzipereka khansa maselo komanso thanzi kwa thupi. Mwangwiro maselo wathanzi mwa masiku angapo kwathunthu bwino pa thunthu, ndi iwo adzakhala khansa.

Koma mukapitiriza kuchita kanthu, ndiye kanthu chidzachitikire chotupa cha. Zimene zikuyamba kokha pamene pali kukhudzana ndi kuwala kwa timaganiza zina, m'zipinda.

Ngati mukufuna kuchita ndondomeko mankhwala khansa ya m'mapapo, ndiye zimenezi ntchito bronchoscope kudutsa maximally mu minofu akhudzidwa. Madokotala kwa PDT laser ntchito ndi mphamvu wochepa, palibe amayaka wa zimakhala sadzalandira chilichonse.

Nthawi yoperekera chithandizo kumatengera pa malo chotupa ndi miyeso yake (kawirikawiri ndi 5 mpaka 45) □. Akufa maselo zimakhala kutha mu masiku pang'ono. Pambuyo kuyezetsa, ngati chofunika, ndondomeko chachiwiri.

Chonde kudziwa kuti mankhwala ndi ntchito ya "Photofrin" si zonse amaloledwa, iwo contraindicated ngati pali:

• fistula pakati pa kum'mero ndi bronchi;
• khansa kuti kufalitsidwa ndi ziwiya lalikulu magazi;
• m'mimba chilonda kapena mitsempha zikuluzikulu;
• ziwengo kuti mankhwala.

mafunso onse kwenikweni kukambirana ndi dokotala wanu pamaso ndondomeko.

Zotsatira zoyipa za PDT

Ambiri mbali zotsatira za ndondomeko ntchito "Photofrin" ndi tilinazo kuchuluka kwa kuwala. Nthawi zambiri kutupa pa malo chithandizo ndi soreness yaing'ono.

Pamene mankhwala alowa chamoyo, izo amasonkhana mu maselo zimakhala mwa masiku angapo ndipo nthawi zina masabata pambuyo mankhwala akhoza kukhala mu maselo. nthawi yonseyi, diso wodwalayo ndi khungu amazindikira kuwala. Kuyambira magetsi owala malo osatetezeka ayamba pathupi ndi chithuza mkati mphindi zochepa.

tilinazo Izi ukapitirize kwa miyezi ingapo, izo zidalira pa makhalidwe a chamoyo. Ife nthawi zonse kupewa dzuwa, koma sizikutanthauza kuti muyenera kukhala mu chipinda mdima. Dosed masana amathandiza chiwonongeko cha zinthu maselo ndi kulimbikitsa kuchira awo.

tilinazo pang'onopang'ono kuchepa, ndipo mukhoza onani, osati kale kuposa mwezi pambuyo mankhwala photodynamic.

Udindo wa zotsatira zina kungakhale kutupa pa malo a mankhwala. Ngati ndondomeko ikuchitika pakhosi pake, nthawi yoyamba padzakhala mavuto ndi Pomeza, ndipo pambuyo mpheto ya phapo - kupuma. Pa kudziwika zizindikiro ayenera mwachangu kuchipatala. zotsatira zina mbali zotsatirazi:

• nseru, kusanza, kupweteka kwa mutu, hiccups - ngati PDT zinachitikadi pa kum'mero;
• kufupika kwa mpweya, chitukuko cha matenda kapena chibayo - kungakhale mankhwala kuwala.

mitundu yonse amenewa ayenera kudziwitsa dokotala.

Ayamikira mankhwala

Mukhoza kupewa zotsatira kwambiri mbali mankhwala, ngati inu mukudziwa momwe yokonzekera ndi kuchita zinthu moyenera pambuyo ndondomeko. Kuti tichite zimenezi, kutsatira malangizo awa:

1. Kupita kuchipatala mankhwala photodynamic, m'pofunika kuti atseke onse nyumba mawindo ndi nsaru, komanso kuona kuti mithunzi nyale akutetezedwa kapena ayi.
2. Utenge kuchipatala kwenikweni magalasi, chipewa (makamaka zipewa zakhonde) kuteteza nkhope. Zovala ayenera zazitali manja, ndi pa mapazi ake - thalauza ndi masokosi (zimenezo, chiyembekezo cha sunscreen ndi zing'onozing'ono).
3. Pambuyo ndondomeko, pasanathe masiku 30, kuti m'pofunika kuti zichitike pa msewu masana, ndipo onetsetsani kuteteza khungu ngakhale pa mitambo pamene inu kutuluka.
4. Onse milandu mwamsanga ndipo mwadzidzidzi, ndi zofunika kusamukira ku madzulo.
5. Home kuwerenga m'pofunika kuteteza maso ku kuwala kolunjika kwa nyale.
6. Pambuyo shampooing ntchito pa choumitsira - mpweya otentha mwina yambitsa thunthu otsala maselo ndi chifukwa redness ndi kutentha.

Ngati mutsata onse malangizo awa, photodynamic mankhwala mu Oncology adzakusonyezani Mwachangu pazipita ndi mtima adzasangalala ndi zotsatira zake.

takambirana

njira iliyonse ya mankhwala sangathe mofanana bwino ntchito zochizira odwala onse. Koma photodynamic mankhwala mu ndemanga Oncology ndi zambiri zabwino. Odwala kuti pambuyo mankhwala chikhalidwe chawo ndinasintha bwino, izo ndi zoona makamaka kwa khansa ya pakhungu ndi matenda ena a pakhungu. Pambuyo PDT pafupifupi palibe mabala, khungu amakhala zotsukira.

Odwala lipoti chithandizo sabweretsa chisoni, pang'ono mavuto. Koma tisaiwale kuti pafupifupi onse odwala kulankhula za chodziwa tilinazo pambuyo ndondomeko. Tiyenera kupewa kuwala ndi molondola kuteteza maso anu ndi khungu kwa naye.

Photodynamic mankhwala mu Oncology ali maganizo oipa kwa anthu okhawo amene sanali kutsatira malangizo a dokotala ndipo sankalola kuulula comorbidities alipo. Tikumbukenso kuti kansa ya m'phuno kapena m'mapapo zovuta mankhwala, kenako mwina mavuto ndi Pomeza ndi kupuma, koma chodabwitsa zosakhalitsa zomwe pang'onopang'ono.

Pambuyo mankhwala, pafupifupi odwala onse ali ndi chifukwa, makamaka ngati ndondomeko ikuchitika katswiri kwambiri oyenerera. Choncho, photodynamic mankhwala mu Oncology ku Novosibirsk anaphunzira chidwi Professor SERGEY Danilovich Nikonov. Iye anayamba mankhwala photodynamic ubongo, komanso njira mankhwala kantseromatoznogo pleurisy, pa nthawiyi iye anamasulidwa mabuku ambiri ndi zokhudza sayansi.

Mu mizinda ina, palinso zipatala kuti amakhazikika kuchiza khansa anafotokoza. Photodynamic mankhwala mu Oncology mu Krasnodar alipo matenda oncologic dispensary №1. malo Izi mankhwala ndi zida ndi luso lamakono, kotero odwala bwino chithandizo sangathe adakayika.

Mwamwayi, tsopano ngakhale matenda oopsa, monga khansa, si chiweruzo. Chinthu chofunika kwambiri - awululire izo kwa siteji pamene mungathe kulimbana nazo. Ndipo zonsezi, ndiye mukufuna kumvetsera kwambiri thanzi lawo ndi kubatizidwa mayeso zachipatala nthawi zonse. Dzisamalire ndi kukhala wathanzi!