"TSifran cha ku Switzerland": analogues, malangizo ntchito ndi mtengo

"TSifran cha ku Switzerland" - kuphatikiza mankhwala ndi yogwira zinthu tinidazole ndi ciprofloxacin. Chinali cholinga zochizira matenda opatsirana wa kapepalako m'mimba ndi matenda wosanganiza, chitukuko chimene chinathandiza aerobes ndi anaerobes.

Iwo anagwira kupanga njira zosiyanasiyana kukonzekera "TSifran". kumasulidwa mtundu wa mankhwala - mapiritsi TACHIMATA, madontho diso, njira yothetsera kulowetsedwa.

Tinidazole aumbike mwa imidazole. mankhwala ali antibacterial ndi ntchito antiprotozoal, ntchito matenda oyamba ndi anaerobes.

Ciprofloxacin limabweretsa mankhwala, kuchita osiyanasiyana ntchito. Kwa iye atengeke aerobic (ambiri a thupi, amene galamu HIV, galamu-zoipa).

Monga wapachiyambi, ndipo analogues "TSifran cha ku Switzerland", mogwira kupirira ntchito.

pharmacodynamics

Tinidazole kumene kumakhudza anaerobes, ndi othandiza kuchiza wathuyo m'mapapo ziwalo ili mu M'mimbamo m'kamwa, mu peritoneum ndi m'chiuno.

Popeza matenda anaerobic ambiri ali osokonezeka (anayamba mchikakamizo cha thupi ndi anaerobic), monga mbali ya mankhwala alipo ciprofloxacin mankhwala, kumafooketsa pa mabakiteriya za thupi aerobes lapansi.

Pharmacokinetics

zinthu zofunika wopangidwa mankhwala oyambirira ndi analogues "TSifran cha ku Switzerland", ndi bwino chosakanikirana kapepala kakuti m'mimba ndipo anawagawira zimakhala madzi a m'thupi. maganizo awo pazipita anati mu thupi pambuyo maola 1.5 pambuyo malowedwe a mankhwala mu kapepala kakuti m'mimba.

Tinidazole ali ndi bioavailability 100%, anafa anasonyeza maola 10-12. Kulankhulana ndi mapuloteni plasma ndi negligible - 12%. Ekskretirovanie amapezeka ya ndulu, tinidazole pafupifupi 25% excreted mu mkodzo sichinasinthe. Metabolites kuletsedwa momwemo. A gawo laling'ono la chigawo cha lotulukira kwa thupi mu chimbudzi.

Ciprofloxacin ndi bioavailability pafupifupi 70% ya kwambiri komanso wodzikonda ntchito pamene m'mimba. Ozama mu thupi ndi chakudya, mbali yomwe ali mu dongosolo ake "TSifran cha ku Switzerland" (analogue a mankhwala yogwira) imatsala pang'onopang'ono. Ciprofloxacin chimamanga kuti madzi a m'magazi pa 20-40%. Tsankho kagayidwe amapezeka m'chiwindi, theka la mlingo akulowa mkodzo limapezeka sichinasinthe. 15% ya ciprofloxacin zimatengera mtundu wa metabolites ndi kuwonetsedwa mawonekedwe 15-30% ya chimbudzi amachotsedwa, Mavesi - ndi ya ndulu. Pakuti tsankho kuchotsa amatenga maola 4 koma nthawi imeneyi kungakhale yaitali odwala okalamba, ndipo ngati wodwalayo anasonyeza matenda a impso.

Zikuonetsa "TSifran cha ku Switzerland" mankhwala

Taganizirani milandu ya amene amalola ntchito ndalama "TSifran" malangizo Buku. Price ndi analogues wa mankhwala kudziwa mphamvu ya mankhwala a matenda otsatirawa:

• matenda wosanganiza, chitukuko cha zomwe zinachitika mchikakamizo cha tizilombo (aerobic ndi anaerobic);
• m'mimba komanso kamwazi wa etiologies zosiyanasiyana (amoebic wosanganiza (bakiteriya ndi amoebic)).

Mankhwala oyenera zochizira matenda wosanganiza:

• njira opatsirana kunachitika wapakamwa ziwalo M'mimbamo (.. mwa T H periostitis, periodontitis);
• bedi zilonda;
• zilonda trophic, ashuga phazi syndrome;
• opatsirana njira zokhudza minofu zofewa khungu;
• mu osteomyelitis aakulu;
• matenda obwela cifukwa ca ntchito ndi akuwuka pansi zochita za tizilombo (aerobes, anaerobes);
• matenda matenda a kutupa chikhalidwe;
• matenda peritoneum ya;
• empyema;
• m'mapapo abscess;
• sinusitis, amene anadutsa mu mawonekedwe aakulu.

contraindications

"TSifran" angathe kumwedwa milandu onse. Reviews analogs kulola kusankha options chithandizo choyenera.

Malangizo loletsa kugwiritsa ntchito mankhwala pamaso pa ena mwa mavuto:

• organic matenda CNS;
• Leaky pachimake porphyria;
• Mafupa kudwala (kulemala hematopoiesis ndondomeko);
• matenda a magazi (m'mbiri).

Contraindications alinso hypersensitivity kwa zigawo zikuluzikulu za mankhwala, kubala ana, kuyamwitsa. mankhwala si kutumikiridwa odwala wamng'ono kuposa zaka 18. Malangizo "TSifran cha ku Switzerland" salola mowa.

The mankhwala okalamba ali zina zapadera, choncho onetsetsani m'pofunika kutsatira malangizo a dokotala nawo. Chenjezo chofunika pamene:

• kuyan'anila m'kukoma chiwindi ndi impso;
• limati convulsive (mbiri);
• khunyu;
• matenda a misala;
• osauka makope mu ubongo;
• mtima atherosclerosis ili ubongo.

Ntchito ya mankhwala, mlingo

"TSifran cha ku Switzerland", ndi analogi ya mankhwala ndi njira zosiyana za ntchito ndi ntchito Mlingo osiyana. Chiphunzitso choyambirira anafuna kuti ntchito mkati, chinajambulidwa pambuyo chakudya (2 nthawi tsiku). "TSifran cha ku Switzerland" ndasambitsa pansi ndi madzi ambiri. Ndi zoletsedwa kuswa umphumphu wa piritsi, muyenera kumwa mu uthunthu wake.

The mlingo wa akuluakulu ndi:

• mapiritsi, monga anthu ciprofloxacin ndi tinidazole pano pa 250 ndi 300 mg, motero - 2 zidutswa;
• miyala yomwe ciprofloxacin ndi Tinidazole 500 mg ndi 600 - 1 ma PC.

Ntchito apakhungu mankhwala kwa maso chofuna amafuna madontho imodzi kapena ziwiri njira. Chithandizo ayenera kuchitidwa ndi imeneyi ya maola 1-4. Ngati chikhalidwe bwino, mungathe kuwonjezera imeneyi.

Zotsatira zoyipa "TSifran cha ku Switzerland" mankhwala

"TSifran cha ku Switzerland" (analogue zinthu zofunika) imfayo ena zochita osafunika.

M'mimba System:

• gepatonekroz;
• chiwindi;
• cholestatic matenda a chikasu ndiyo (ndi chiopsezo chachikulu cha chitukuko mu odwala matenda chiwindi);
• m'mimba, flatulence, kupweteka m'mimba;
• kunyansidwa ndi kusanza;
• zosasangalatsa kukoma mu zitsulo pakamwa;
• kusafuna chakudya;
• dryness wa mucous zilonda za m'kamwa zibowo zam'mano.

mantha dongosolo:

• thrombosis zokhudza mtsempha wamagazi oziziritsa;
• kukomoka;
• Mkulu ICP;
• migraine;
• chizungulire, mutu;
• zochita psychotic;
• thukuta;
• kusagona tulo;
• kugwedeza;
• kufooka, kutopa;
• kupweteka;
• neuropathy zotumphukira;
• dysarthria;
• mavuto ndi kugwirizana kayendedwe.

Zolemba ndi zina zotsatira osafunika "TSifran cha ku Switzerland" malangizo. Price mu pharmacies analogues kudziwa osati efficacy wa mankhwala, komanso pamaso pa zotsatira zina zoyipa.

Zopempha:

• amaona masomphenya;
• kusintha kununkhiza;
• dysgeusia;
• osauka kumva.

dongosolo mtima:

• otsika magazi;
• kusintha kayendedwe ka mtima;
• tachycardia.

dongosolo mkodzo :

• interstitial nephritis;
• mavuto ndi excretion wa mkodzo;
• mapangidwe yambiri mkodzo;
• impso glomerular chotupa;
• mkodzo m'menemo kupanga timibulu mchere;
• mtima magazi mu mkodzo zikuchokera.

Zizindikiro zotheka a chifuwa ndi zotsatira zina zoipa, kusintha mu magawo choyezera, zipolowe zosiyanasiyana m'dzikoli hematopoietic.

Mwanjira mankhwala

"TSifran cha ku Switzerland" (analogue wa chigawo yogwira) sayenera pamodzi "ethionamide". mankhwala ali pamodzi ndi mankhwala ena ndi sulfonamides.

Pamene ntchito ndi "pentobarbital" anatero mathamangitsidwe wa kagayidwe. Mankhwala timapitiriza kanthu Mowa ndi anticoagulants.

Kusamala

Pa mankhwala ayenera zochepa ngati n'kotheka kukhala mchikakamizo cha dzuwa. Iwo amaletsedwa kuchita zinthu zimene mankhwalawa mankhwala akhoza zingawononge thanzi (zofuna chisamaliro, mofulumira mawonetseredwe a galimoto ndi zochita maganizo). Pa mankhwala, kuwunika magazi zotumphukira.

Analogs, ndemanga, mtengo

Pamene kugawa "TSifran cha ku Switzerland" analogues, mtengo ndi zofunika odwala. The zambiri ntchito mankhwala. mapiritsi ndalama zili ndi zinthu zofunika 250 ndi 300 pafupifupi 36-460 rubles mtengo mg kumene 500 ndi 600 mg zigawo zikuluzikulu - za 79-500 rubles.

Kodi m'malo "TSifran cha ku Switzerland"? analogs Russian ndi mtengo. Mankhwala poyambirira m'malo Mwachitsanzo, "Ciprofloxacin" (10-25 rubles). Indian Anzawo, mukhoza kusankha "Tanidazol Ciprofloxacin +" kapena "Tsiprolet A" (150-325 rubles). Ndi mankhwala awa ali makamaka m'malo mwa "TSifran cha ku Switzerland".

Tikayang'ana ndemanga, mankhwala choyambirira uzigwirizana bwino ndi chimfine, makamaka ngati matenda chinayamba. Pamene ntchito mu masiku oyambirira a kuzungulira kusamba, timatha inu kuchiza ambiri kutupa wamkazi. "TSifran cha ku Switzerland" msanga atsogolere alili.

Kwenikweni mankhwala ntchito pambuyo ntchito ndipo pa nthawi imene otaya mu thupi kutupa kwambiri, limene kwa nthawi yaitali chiyani kutha, chifukwa pali zotsatira ambiri mbali. ndemanga makasitomala amanena kuti analogues si bwino ndipo bwino analekerera.

Mankhwala "TSifran cha ku Switzerland" kutenga pokhapokha kuona ndi dokotala paudindo. Sikuti kudzimvera medicate, chifukwa zotsatira zake zikhoza kukhala zoopsa.