Analogs ndi malangizo ntchito "lomefloxacin"

Kodi m'malo mankhwala monga "lomefloxacin"? Analogs wa mankhwala, cholinga chake, ndi zoletsa kugwiritsa ntchito katundu achire zafotokozedwa pansipa. Mudzaphunziranso za momwe ntchito bwino chida ichi, ndi mlingo zomwe.

Mtundu wa mankhwala, ma CD ake, ndi ziwalo zikuluzikulu

Amene phukusi alipo la ndalama? Kumene kumupatsa malangizo pa ntchito? "Lomefloxacin" - piritsi, anaikidwa matuza ndi mmatumba mu mapaketi pepala, pamodzi ndi chidule cha.

Kodi zosakaniza kumaphatikizapo mankhwala? The yogwira pophika mankhwala ndi lomefloxacin hydrochloride. Komanso amaphatikizapo zigawo zina wothandiza.

The achire katundu wa mankhwala

ndi mankhwala "lomefloxacin" n'chiyani? limati Manual kuti bactericidal antimicrobial mankhwala amene ali ndi ndalama gulu antibiotikopodobnyh, ndiye fluoroquinolones, ndipo umaimira m'badwo wachiwiri wa mankhwala.

Chimene chimayambitsa antimicrobial efficacy wa mankhwala pansi pa cikwati? katundu amenewa "lomefloxacin" Mapale (400 mg) anali analandira zikomo chakuti chuma chawo yogwira amatha zotsatira kutchinga pa DNA gyrase (i.e. bakiteriya enzyme) amene amathandiza supercoiling. Komanso, wothandizila zimenezi zimapangitsa pawiri khola (zovuta) ndi tetramer ake ndi amasokoneza DNA galamafoniyo ndi tizilombo ta maselo bakiteriya, unkawononga anayamba.

Lofotokozedwa ntchito medicament pamaoneka ndi zoipa aerobic mabakiteriya monga gonococci ndi, nsomba, Pseudomonas, Haemophilus ndi Escherichia coli, kolera tizilomboto, meningococci, Shigella, Morganella ndi zina zotero. Komanso medicament "lomefloxacin" (400 mg) ogwetsa zotsatira pa Proteus, chlamydia, Campylobacter, mycoplasma, legionella, ena pneumococci ndi staphylococci.

Sitingathe kunena kuti mankhwala anati kwambiri polimbana Mycobacterium TB. Iye akhoza kuchepetsa nthawi kuchotsa awo, komanso resorption oyambirira infiltrates zilipo.

Achire zotsatira "lomefloxacin" anatero ngakhale pa woipa ake otsika magazi. Ngati kukana izi anati kawirikawiri.

luso kayendedwe mapiritsi mankhwala

Kodi odzipereka anati medicament? Zimene limanena pa malangizo ntchito? "Lomefloxacin" ali absorbency wabwino. Atalandira mankhwala ake pachimake plasma ndende akwaniritsa mkati mphindi 55-85.

The plasma mapuloteni chimamanga kuti mankhwala okha pa 10%. Ndiponso, ali ake katundu wabwino mayamwidwe ziwalo zosiyanasiyana ndipo zimakhala (kuphatikizapo kumaliseche kwa m'mfundo, njira kupuma, ziwalo ENT, ziwalo m'chiuno, mafupa, pamimba, zimakhala zofewa, etc.), pamene wokhutira ndi nthawi 5-7 apamwamba plasma.

Tikumbukenso kuti ena lomefloxacin zimapukusidwa ndi ndipamene ena ofanana angapo.

Nyengo ya excretion wa mankhwala ndi 9 maola. Linanena bungwe izo kudzera katulutsidwe tubular mu mkodzo (70-85%) ndi ndowe (25-30%).

Zikuonetsa kuti zoti njira

anthu ochepa mukudziwa, koma mankhwala unyolo angapezeke osati mapiritsi "lomefloxacin", komanso mankhwala "lomefloksatsin + pyrazinamide wokhala + wa ethambutol + Prothionamide + Pyridoxine". Pankhaniyi onse anati medicament ali anasonyeza ntchito:

• matenda (purulent) khungu ndi minofu zofewa (kuphatikizapo amayaka, mabala kachilombo, etc.);
• osteomyelitis;
• chlamydia ndi chinzonono (kuphatikizapo Blepharoconjunctivitis ndi chlamydial conjunctivitis);
• matenda thirakiti m'mimba (mwachitsanzo, kolera, kamwazi, typhoid malungo, salmonellosis);
• matenda kupuma (kuphatikizapo chifuwa, mtundu kobwereza);
• biliary thirakiti matenda;
• matenda m'dera urogenital (mwachitsanzo, urethritis, prostatitis, cystitis, pyelonephritis);
• TB m'mapapo mwanga (kuphatikizapo chithandizo cha anthu ndi mitundu mofulumira patsogolo matendawa, komanso kuchuluka kukana kuti "isoniazid wa" ndi "Rifampicin" ndi kukana kuti mankhwala amphamvu);
• isanayambe kapena itatha transurethral opaleshoni (yekha zolinga prophylactic).

Ziletso poika mapiritsi antimicrobial

Nthawi zina, mungathe kugwiritsa ntchito mankhwala pansi pa cikwati? Kodi izi limatiuza malangizo Buku? "Lomefloxacin" ali contraindicated ntchito:

• gestation;
• Kuyamwitsa;
• tilinazo munthu wa mankhwala a gulu fluoroquinolone;
• monga ana (mwina chopinga chitukuko chigoba).

Malangizo ntchito

"Lomefloxacin" - mapiritsi kuti pokhapokha wasonyeza kuti ingestion. Iwo ayenera kumwedwa kamodzi pa tsiku, kaya chakudya, kumwa za 230 ml ya madzi wamba.

Kutalika kwa mankhwala ndi mankhwalawa zimadalira matenda, komanso pa kukula kwa matenda ndi tilinazo tizilomboto lapansi.

Wopepuka pachimake matenda ndi bronchopneumonia otaya ankachitira mlingo wa mg wa 400 mankhwala pa masiku khumi.

Mankhwalawa chlamydia (urogenital), kuphatikizapo matenda bakiteriya ndi chlamydial, gonococcal ndi chlamydial, odwala kutumikiridwa 400-600 mg wa mankhwala patsiku, ndi nthawi ya ntchito kuti masiku 28.

Chithandizo cha musabise kobvuta chibayo ndi aakulu mtundu matenda nazo mlingo tsiku wofanana 400-800 mg wa mankhwala, kwa masabata awiri.

Pamene mycoplasma matenda ankaona mankhwala Kwalamulidwa kwa 400-800 mg ndi patsiku, ndi nthawi ya utsogoleli wa miyala mu masabata 3.

Mkodzo thirakiti nthenda amenable mankhwala 400 mg wa mankhwala. Ndi mankhwala a milandu wopepuka anachita kwa masiku 5, ndi zovuta - masiku 14.

Mu chinzonono pachimake mankhwala "lomefloxacin" analimbikitsa kutenga mlingo wa 600 mg. Koma mawonekedwe aakulu a matenda, mankhwala ake ikuchitika limodzi ndi immunotherapy yeniyeni. Pankhaniyi, kutenga mankhwala pa mlingo yomweyo tsiku kwa masiku 5.

Chithandizo cha TB m'mapapo mwanga zingatenge masiku 14-30 (zina mpaka miyezi 3). Chotero matenda kuchitira mankhwala mlingo wa 200 mg kawiri pa tsiku.

Pamene asonyeza pathologies aimpso kapena chikhalidwe zolimbitsa, komanso anthu akukumana hemodialysis, "lomefloxacin" ndi kutumikiridwa mu kuchuluka kwa 400 mg pa tsiku, ndi kuchepa ake china 200 mg.

The chodabwitsa cha khalidwe oipa

zotsatira zoipa zingachititse mankhwala "lomefloxacin"? Atsogolereni mfundo zimene zotsatirazi:

• bronchoconstriction, kuchuluka ntchofu katulutsidwe, nseru, chifuwa, dysphagia;
• dyspnea, kusanza, matenda kupuma, kutsegula m'mimba, Chotupa chija;
• zizindikiro za chimfine, dysgeusia, epigastric ululu, bloating;
• kukwezedwa kwa michere chiwindi, dryness mkamwa, m'mimba magazi;
• kudzimbidwa, arthralgia, ng'ombe omangana, kusintha chinenero cha mtundu, myalgia;
• pseudomembranous matenda a m'matumbo, mutu, kusintha njala, vasculitis, chizungulire;
• kusowa tulo, chifuwa wachifundo ndi kumbuyo, kutopa, manjenje, timafuna malaise ambiri, maganizo, kenaka utentha mamba;
• hyperkinesia, kutopa, kupweteka, kuyerekezera zinthu m'maganizo;
• ululu maso, phokoso, ndi ululu makutu;
• dysuria, kuchuluka chilakolako chogonana, hematuria, paresthesias;
• crystalluria, amaona masomphenya;
• albuminuria, glomerulonephritis, Leucorrhœa, edema, polyuria, epididymitis, vuto kukodza, orchitis, tenesmus;
• cyanosis, anuria, hypotension, vaginitis, tachycardia, arrythmia, perineal ululu, bradycardia;
• intermenstrual magazi, thrombocytopenia, ukazi candidiasis, m'mnyewa wamtima infarction, cardiomyopathy, phlebitis;
• Kukula kwa matenda a mtima ndi angina, purpura, matenda cerebrovascular, kuyabwa khungu;
• embolism m'mapapo mwanga, photosensitivity, kuwonjezera fibrinolysis, zotupa lymphadenopathy, zidzolo;
• epistaxis, erythema (zilonda), kumverera kuzizira, gout, otentha cheza;
• superinfection, hypoglycemia, candida, kumva ludzu.

An ambiri osokoneza mapilisi

Ndi ambiri osokoneza mapilisi "lomefloxacin" odwala kuona nseru, zotupa erosive wa mucosa m'mimba, kutalikitsa QT nthawi, chizungulire, khunyu, chisokonezo, komanso kuchuluka zosiyanasiyana chokhwima.

Chifukwa hemodialysis ambiri osokoneza kumatanthauza ankaona mankhwala osamveka pamwamba zinthu ikuchitika pamaziko zizindikiro zilipo.

Mogwirizana ndi mankhwala ena

Ndi kuphatikiza "lomefloxacin" ndi "theophylline" kagayidwe lake pafupifupi imathetsa.

Pamene makonzedwe munthawi yomweyo ya Mankhwalawa ayenera kumwedwa ndi sucralfate anapanga chelate maofesi kuti kuchepetsa bioavailability wa lomefloxacin. N'chifukwa chake imeneyi pakati pa phwando anati medicaments akhale maola osachepera 4.

Olowa ntchito "lomefloxacin" ndi mlingo waukulu wa Kafeini prolongs hafu ya moyo wa masika.

Mu mankhwala TB sayenera amachitika zikufanana ndi phwando la ndalama "Rifampicin", mwinamwake izo zidzapangitsa kuti chidani kanthu.

Munthawi yomweyo chithandizo ndi NSAIDs kumawonjezera kawopsedwe wa mankhwala ndi zingachititse khunyu.

"Lomefloxacin" akhoza kuonjezera dzuwa la anticoagulants kwa makonzedwe m'kamwa.

Mankhwala, amene blockers wa katulutsidwe tubular, ziletsa excretion a "lomefloxacin".

ayamikira yeniyeni

Ngati matenda aimpso amafuna kusintha kuvomerezedwa mlingo, potsata pa QC zokhazikitsidwa.

chithandizocho muyenera kupewa chikoka yaitali aliyense magwero UV kuwala, kuphatikizapo dzuwa.

Vitamini wothandizila monga zina zosiyanasiyana mchere ayenera kutenga mphindi 120 pambuyo kapena patsogolo pa ankaona kulandira mankhwala.

mankhwala ofanana

Medicament "lomefloxacin" ali analogues ambiri. Waukulu mmalo mankhwala akatswiri zotsatirazi: "Abaktal", "Elefloks", "Zanotsin", "TSifran", "Avelox", "Tsiprolet", "Zofloks", "tsiprinol", "Kvintor" "Ciprofloxacin", "Levofloxacin "" tarivid "," Levotek "," pefloksatsina "," Levofloks "," Ofloxacin "," Norbaktin "," Ofloks "," norfloxacin ".

Miyala "lomefloxacin": Ndemanga

Pamene atafotokoza wothandizila opatsirana kuti amakhudzidwa m'badwo wachiwiri wa fluoroquinolones, komanso kusankha olondola a Mlingo mankhwala ndi chithandizo yaitali, ndemanga za njira yatsopano mwangwiro positive.

Malinga ndi mawu odwala, mankhwala watsimikizira yokha ngati mankhwala ogwira antimicrobial kuti mokwanira chikuchita ndi tizilombo zosiyanasiyana pathological. Komabe, anthu ena amene amati mankhwala amayambitsa chitukuko cha zotsatira zina mbali, koma monga ulamuliro, akudwala chimatanthauza mu chikhalidwe kapena okha yomweyo pambuyo pa mapeto a mankhwala.