Aspartate aminotransferase kuchuluka, zikutanthauza chiyani zifukwa

Thupi lathu, mwina tinganene kuti ambiri "zipangizo zatsopano" imene analenga amayi Nature. Mu izo, bungwe ndi wapadera ake "dongosolo" ndi mphamvu zake, iye si monga zodabwitsa monga ndi chidwi. Ndipo ngati inu wofufuza kuphunzira lake lonse, n'zotheka kukumana ambiri ndithu mawu ovuta. Nthawi zambiri atamuyezanso mungapeze ngati unpronounceable mawu monga aspartate aminotransferase kuchuluka. Pakali pano, akunena za kwa amino asidi pogawanikana pamawere mutu. M'pofunikanso kuti adziwane bwino ndi mawu pang'ono.

Kodi mtundu wa yaitali?

Mu mawu anapatsidwa amatanthauza puloteni imene nawo kuti akuwaza ndi, ntchito, pafupifupi zidulo aliyense kwa amino mu chamoyo wathu. Yafupika anaitana SGOT kapena Ast imaonekera mu zilembo zazikulu. enzyme ili mu zimakhala ziwalo zambiri, monga:

• chiwindi;
• mtima;
• minofu mitsempha;
• impso;
• minofu;
• kapamba;
• ndulu;
• kuwala;
• ubongo minofu.

Komanso, ambiri enzyme mu zimakhala za mtima, impso, maselo mitsempha, chiwindi.

Choncho, matenda a matenda chilichonse chogwirizana ndi matupi awa zikutanthauza kuti aspartate aminotransferase kuchuluka. Mu mapapo, ndulu ndi kapamba enzyme kuchuluka si chachikulu kwambiri. M'mene thupi mwamuna wosiyana ndi akazi mkulu ntchito zinthu.

magwiridwe Ast

The enzyme ndi mapuloteni molekyulu umene inakhazikitsa minofu ma ya ziwalo. akuphatikizapo unakhazikitsidwa asayansi Russian mu 70s lapansi. Ntchito enzyme ndi ndi kupititsa patsogolo zochita amuzolengedwa mu maselo. Ndi nawo vitamini B6, n'zotheka kufotokoza amino zidulo. Kusintha zovuta zidulo ambiri kwa amino, kuphatikizapo aspartic, mapangidwe pawiri latsopano. Zinali uyamiko kwa Iye kaphatikizidwe wa shuga, lomwe ndi lofunikira kwa thupi lathu.

Features Ast

Aliyense wa ife posapita nthawi anakumana ndi mawu monga aspartate aminotransferase kuchuluka. Zimatanthauza chiyani, iye sadziwa aliyense. Pa nkhani imeneyi, tiyenera kuulula nsalu yotchinga. Mu wathanzi chamoyo enzyme ali maselo a ziwalo anati mkati, ndi ponseponse. Only mbali yaing'ono ya Ast akhoza kudutsa mu mwazi. Information - ndende ya enzyme mu mtima kuposa kuchuluka kwa magazi nthawi 10 chikwi.

Koma ngati minofu ya chiwalo ndi chawonongeka, ndi aspartate aminotransferase, kumasuka, mu magazi ndi kuchuluka kwa enzyme akuyamba kuonjezera. The kukula kugunda zimadalira mlingo wa kuwonongeka minofu. Mwachitsanzo, matenda a infarction m'mnyewa wamtima, Ast ndende kufika pachimake tsiku.

Nthawi zina, mlingo enzyme mwina upambana mlingo wa nthawi 5, ndi chizindikiro akhoza kusungidwa kwa masiku 7. Ndiyeno munthu amaganiza kuti aspartate aminotransferase (Ast) chinawonjezeka, zikutanthauza chiyani? Izi ntchito yapamwamba ndi chizindikiro cha matenda aakulu a wodwalayo, nthawi zambiri umatha akumane zotsatira zake.

Ngati kuwonjezeka woipa enzyme kumachitika pang'onopang'ono kuwonjezeka mlingo, izo zimatanthauza kuti zone infarct kumawonjezera. aspartate aminotransferase ntchito kungakhale ndi kufa kuchokera kwa minofu chiwindi.

Kodi kusokoneza ntchito mkulu wa Ast?

Kawirikawiri mkulu wa ndende Ast mu mtsempha wa magazi chimachititsa izo m'mnyewa wamtima infarction. Pamene ndalamazo wa enzyme Nthawi zina zoposa 10 ponseponse, ndi apamwamba ndi, wamkulu kudera la zotupa mtima minofu. Pa tsiku lachinayi la mankhwala kawirikawiri anapatsidwa reanalysis. Zotsatira zake zimasonyeza, aspartate aminotransferase kuchuluka kapena ayi. Mu nkhani ya mankhwala ogwira ayenera ndichepe ndende zake.

Mkulu mlingo wa Ast zingaoneke mu zotupa a chiwindi chifukwa zinthu zingapo:

• matenda Oncological.
• Mowa poizoni.
• Kunenepa.
• Kupezeka kwa matendawa.

Only mu nkhani iyi, kuti apange matenda zolondola, m'pofunika kuchita mayesero zina. Komabe, milingo apamwamba enzyme mwina anthu mwinamwake wathanzi. Mwachitsanzo, ntchito zingakhale:

• Ana pamaso kutupa.
• Mu akazi pa trimester mimba.
• Ngati ntchito kwambiri mowa.
• Akavala mankhwala ena: valerian, mankhwala osiyana kapena paracetamol.

Great thupi, nayenso, ndi chikutanthauza kungasokoneze. Komanso, ngati aspartate ndi kuchuluka, zifukwa akhoza obisalamo mu ntchito za kukonzekera zochokera barbituric asidi wambiri wa kulera angathe kutsogolera ndi kuwonjezeka Ast.

Zifukwa kuwonjezeka Ast

Zimayambitsa chinawonjezeka kaperekedwe ka enzyme, monga tanenera kale pamwamba, zikhoza kukhala m'mnyewa wamtima infarction. Ndi matenda izi 95-98% odwala onse owerengedwa ntchito mkulu wa aspartate aminotransferase. Mtengo kungakhale mayunitsi mpaka 3,000 chizindikiro. / L. Nthawi zina, mpweya wambiri wa enzyme anaona mu necrosis chiwindi. Matendawa, nayenso choncho chifukwa zosiyanasiyana za matenda. Mlingo wa Ast Pankhaniyi kuposa mfundo yachibadwa nthawi 10-100.

Ena mwa matenda ena Dziwani angina, pachimake kapamba, kutsekeka kwa ducts ya ndulu, maselo a khansa kapena metastases chiwindi. ndende ina enzyme akhoza chinawonjezeka chifukwa choipa, ndi ndondomeko lamoto kuyamba kufa ena a minofu poyera kuti kutenthetsa mantha. Izi iwonso monga wodwala mu nthawi postoperative.

Kodi aspartate aminotransferase adakula mwana, kungasonyeze pamaso pa chiwindi, akulu dystrophy, pachimake myocarditis, matenda a chikasu ndiyo.

Chifukwa kutsitsa Ast

misinkhu enzyme mwina osati pokuza komanso ndichepe. Izi zimachitika pa zifukwa zosiyanasiyana. Monga ulamuliro, kumachitika mu amayi apakati. Nthawi zina ana ndi akulu chifukwa akulu dystrophy, kuvulala kwa kusinthasintha mwamphamvu, infarction oziziritsa, hypothyroidism kapena pachimake kapamba anaona kungachepetse mlingo aspartataminotraferazy. Chifukwa ndi vuto losowa vitamini B6 kapena ndi chotupa chiwindi amadziwikanso matenda akusowa ya mapuloteni molekyulu.

Zikuonetsa kuti cholinga kusanthula

kusanthula kudziwa mlingo wa enzyme Ast ayenera idzachitika kuti azindikire pamaso pa pathologies akuluakulu:

• zimachitika ngati njira khansa maselo a chiwindi;
• ngati pali metastases;
• aspartate aminotransferase kuchuluka magazi zingasonyeze pamaso pa mononucleosis matenda kapena tizilombo a dongosolo lymphatic;
• mtundu wa matenda autoimmune (mwachitsanzo, DMD-Becker) ;
• m'mnyewa wamtima infarction;
• matenda enaake;
• kusanthula amasonyezanso pamaso pa mitundu iliyonse ya chiwindi, kuphatikizapo necrosis chiwindi.

Komanso, chosayenerera minofu ndi chiwindi, monga osachepera, ndi kuganiza za yobereka kusanthula.

Only zotsatira zake zingakhale kutsimikizira kapena kutsutsa matenda. Izi adzalola kuti atenge miyeso zofunika mu nthawi. Ngati kusintha kulikonse zazikulu zachitika, ndiye kuti bwino.

Kukonzekera - chikhalidwe zofunika

Monga kupita kwa ena mayeso pochitika kuwunika ayenera kulandira chithandizo kwambiri monga kumwa mankhwala, kaya ndi dokotala kusankhidwa mankhwala kapena decoction azitsamba, zingathe kusokoneza zotsatira za kuwunika kuti si zoona.

Choncho, ndendende, aspartate aminotransferase kuchuluka kapena ayi, muyenera kusiya kumwa mankhwala. Ngati pa zifukwa zina izi sizotheka, tiyenera kudziŵitsa dokotala amene ayenera kupereka mfundo zonse za mankhwala. Ndicho, mlingo ndi nthawi ya umwana wake. zasayansi akazi kuyezetsa angawononge mimba.

Analysis ndi ntchito mfundo

Zofunika kufufuza ndi oyeretsedwa venous magazi kapena seramu. zochepa chabe pamalangizo ake amachitidwa pa chopanda kanthu m'mimba m'mawa. Ndondomeko lonse satenga nthawi yambiri ndipo akutenga malo popanda ululu. Chifukwa ndi wokonzeka pambuyo maola 6-10. The seramu zikhoza kusungidwa kwa maola 48 pa kutentha madigiri 15-25. Mu zikhalidwe ozizira (2-8 ° C) kuti amalimbikira 6 masiku.

Koma funso, kumene kuli kotheka pochitika kudzipenda moteromo, m'pofunika ntchito kwa Laboratories apadera kuti achite nkhani amuzolengedwa. Nthawi zina, kuphunzira Ast (aspartate aminotransferase) kuchuluka kapena zachilendo, mukhoza kupita kuphunzira mu chipatala pa nyumba yake kapena aliyense bungwe zachipatala boma. Only choyamba tiyenera kupeza ngati labu ake zida zina zofunika ndi zida kuwunika.

misinkhu Normal gulu lililonse la anthu awo. Mwachitsanzo, anthu ambiri Ast mu akhanda ndi 25-75 U / L, pamene ana pang'ono akulu (zaka 1-18), ndi 15-60 U / L. misinkhu Normal azimayi osiyanasiyana monga 10 36-U / l, ndi amuna - kuchokera 14 20 U / L.