"Diferelin": ndemanga, analogs, ndi malangizo ntchito

Mmodzi wa mankhwala zothandiza kwambiri pofuna kuthana ndi kudwala kwambiri chifukwa cha dongosolo amuna ndi akazi ubereki, ndi mankhwala "Diferelin". Malangizo, mtengo wa mankhwala kawirikawiri akambirana odwala maonekedwe apadera. Monga mwachizolowezi, ndi mankhwala ali mbali yake ndi adani. M'nkhani ino tikambirana limagwirira cha zochita za mankhwala ndi makhalidwe ake pharmacological.

achire

Kukonzekera "Diferelin" ndi mankhwala ndi kanthu antigonadotropnym. Ndipotu, ndi odana ndi mahomoni, monga amatha kubisa yopanga luteinizing timadzi ndi follicle-zolimbikitsa timadzi mu wamkazi ndi testosterone anthu. Choncho, "Diferelin" mankhwala yogwira ntchito zochizira fibroids uterine, endometriosis, khansa, kutha msinkhu kumayambiriro achinyamata ndi matenda ena.

Kapangidwe ndi Kaonekedwe

Kukonzekera "Difelerin" panopa zizipezeka mmodzi mawonekedwe mlingo - lyophilisate kulenga zothetsera. Pa nthawi yomweyo, izo zimapangitsa mitundu itatu ya zipangizo, woipa osiyana wa chinthu udakali ndi cholinga osiyana:

• "Diferelin" 11,25 mg wa ndi 3,75 mg - mu mnofu jekeseni;
• "Diferelin" 0.1 mg - jekeseni subcutaneous.

Mu ntchito, madokotala ndi odwala posachedwapa amatchedwa mitundu takambiranazi, za mankhwala, kuwonjezera mutu zithunzi zake kufotokoza zili wa chinthu chachikulu.

Monga pophika mwakhama mankhwala "Diferelin" mavoti omwe ambiri abwino amachita triptorelin pamoate. Kuti ochitachita pa mtima kutchulidwa zotsatira achire ndi pharmacological.

Medicament "Diferelin" amagulitsidwa makatoni, imene pali mabotolo a lyophilisate ndi syringe ndi masingano awiri. Komanso, nambveka vayozi wa zosungunulira. Izo zikhoza kukhala zosiyana. Ngati lyophilizers "Diferelin" 3,75 ndi 11,25 mannitol ntchito makamaka, ndi medicament mu ndende ya 0.1 mg ndi ntchito zambiri saline.

zotsatira achire "Diferelin"

Kuchokera amuzolengedwa pamaso yogwira timadzi mankhwala ndi analogi wa GnRH apanga ubongo imene imalamulira kutentha. Iwo zimakhudza pituitary England ali ndi udindo kwa kupanga timadzi kugonana, motero malamulo ntchito ya dongosolo amuna ndi akazi ubereki: ku prostate, n'kuwasanganiza, chiberekero, machende. Iwo likukhalira kuti nthawi yopanga kugonana mahomoni mankhwala "Diferelin".

Reviews ntchito zake amasonyeza kuti ali ndi amphamvu odana ndi chotupa ndi antigonadotropnym kanthu ndi othandiza pa matenda a pathologies ena. Mwachitsanzo, munthu akakhala wosabereka, mankhwalawa limaleka yopanga luteinizing timadzi, amene zoipa amakhudza ovulation, potero kukula mwayi wa mimba. A medicament khansa, izi zimachepetsa milingo testosterone kuti ziro, ndilo khalidwe kwa castrates, ndi kuonjezera mwayi wodwalayo wa ndiyotani pakuchotsa khansa.

Kugwiritsa matsenga "Diferelin" ndi endometriosis. zimakhudza awo pa ulimi wa mahomoni kugonana pang'onopang'ono akulowa mkazi mu boma yokumba ya kusintha ndipo potero amakwiya manja endometriodnyh foci.

zikuonetsa

Malinga woipa ali zotsatira zosiyana pa chamoyo mankhwala "Diferelin". Kugwiritsa ntchito mankhwala mankhwala amadalira zili mbali yaikulu yogwira pophika. Mwachitsanzo, jekeseni "0.1 mg wa Diferelin" tikuonera osabereka, kwa revitalization wa kukondoweza yamchiberekero ndi ovulation mu lidzawagwiritsenso.

Kugwiritsa ntchito mankhwala pa ndende ya 3,75 mg wa akamaganizira polimbana ndi khansa prostate, fibroid chiberekero, kupsa msanga, maliseche ndi extragenital endometriosis, lidzawagwiritsenso ndondomeko.

Milandu yoopsa kwambiri kansa ya prostate ndi metastases ndi endometriosis aakulu, woikidwa phwando "Diferelin 11,25 mg." ntchito yake kwambiri kusintha mwayi wodwala kuchira.

Malangizo ntchito

Medicine "Diferelin 0.1 mg ndi" ntchito yochepa yaitali ndondomeko lidzawagwiritsenso moyang'aniridwa okhwima zachipatala. Iwo kutumikiridwa tsiku lina ampoule kwa tsiku lachiwiri kusamba. Kutalika kwa mankhwala anatsimikiza ndi makhalidwe munthu wa thupi wamkazi.

Koma mankhwala "Diferelin 11,25 mg wa" kutumikiridwa odwala miyezi itatu iliyonse. Ndipo amuna akhoza kupanga jekeseni pa nthawi iliyonse, ndi akazi - yekha mu masiku asanu kuzungulira kusamba. Kutalika kwa mankhwala ndi mankhwala kumatenga miyezi itatu kapena isanu ndi umodzi, pamene miyezi isanu ndi umodzi, izo osavomerezeka.

Uthunthu linafalitsidwa kwambiri ntchito mankhwala "Diferelin 3,75". Umboni kusonyeza pa mphamvu ya mankhwala. Komanso, ndi yabwino kwa ntchito, chifukwa sikutanthauza makonzedwe tsiku kwa nthawi yaitali. Majekeseni "Diferelin 3,75 mg wa" mankhwala kawirikawiri anachita kamodzi pamwezi. Izi akukwana kuonetsetsa yobereka yogwira mu m'magazi pa Mlingo achire. Tiyeni tione ntchito imeneyi medicament dera matenda osiyanasiyana.

khansa Prostate

Amuna si anasonyeza kuti khansa mankhwala "Diferelin". Jekeseni wa wodwalayo anayikidwa pa masiku twente eyiti, kotero kuti imeneyi pakati ka mankhwala ndi masabata anayi. A mlingo umodzi wa medicament ntchito - botolo limodzi 3,75 mg. Kutalika kwa makonzedwe mankhwala anatsimikiza ndi mlingo wa machiritso wa wodwalayo.

endometriosis

Jekeseni wa mankhwala "Diferelin" akazi ndi endometriosis zimapezeka masiku asanu lotsatira kusamba. A mlingo wotsatira wa mankhwala opangidwa mu masabata anayi, ndi chithandizo Inde kumatenga okwana miyezi 3 mpaka 6. Tiyenera kukumbukira kuti mankhwala akhoza osati pamodzi ndi ntchito kulera m'kamwa.

Mankhwalawa endometriosis amachititsa yokumba kusintha (amenorrhea) kukonzekera "Diferelin". Reviews odwala Komabe, kusonyeza kuti pambuyo pa kutha kwa chithandizo msambo abwezeretsedwa m'miyezi yochepa, nthawi zina chaka. Mobwerezabwereza mankhwala ndi mankhwalawa ndi endometriosis kobwereza, monga ulamuliro, si anatumizidwa - Mwaichi, zina, mankhwala sakhala ogwira.

Adrenarche

Ana atagwira msanga msinkhu mankhwala "Diferelin" kutumikiridwa kamodzi pa masiku 28. Choncho mlingo umodzi wa ntchito masamu ndi kulemera kwa wodwalayo. Ana ndi kulemera pa makilogalamu 20 anayambitsa vial (3.75 mg), ndi ana akalozera ang'onoang'ono - theka ampoule (1.875 mg). Kutalika kwa mankhwala anatsimikiza ndi dokotala nawo malingana ndi changu cha normalization wa alili.

fibroids uterine

Mankhwalawa matenda kutumikiridwa kamodzi pa mwezi kwa osakwatira mankhwala botolo "Diferelin". Ndipo madyerero ake ayenera idzachitika pa masiku asanu a msambo wa wodwalayo. Anasintha jekeseni wa mankhwala kumachitika pa masabata anayi. Nthawi mankhwala ndi ambiri miyezi itatu.

ambiri osokoneza

Panopa sizinaulilire Mulimonsemo mankhwala "Diferelin" ambiri osokoneza. Umboni amasonyeza chitetezo ake wachibale. Komanso, mankhwala ali ziribe mphamvu pa ndende ndi luso kulamulira njira avundulidwe. Choncho, m'kati mwa mankhwala ndi mankhwala ndi poiyendetsa.

zotsatira zoyipazi

Pamene ntchito "Diferelin" mankhwala akhoza kuona zotsatira zotsatirazi mbali:

• zizindikiro za msana psinjika chingwe;
• padzakhala ululu;
• Angioedema, urticaria, oyabwa;
• ureteral kutsekeka;
• mutu;
• fupa demineralization;
• utachepa potency;
• ukazi dryness;
• thukuta;
• kuchepetsa testes;
• kusintha kukula bere;
• hypogonadotropic amenorrhea;
• hypertrophy wa thumba losunga mazira ndi;
• menorrhagia;
• asthenia;
• nseru, kusanza;
• oopsa;
• otentha cheza;
• amaona masomphenya ;
• maganizo lability;
• hematuria;
• zikamera kulemera owonjezera;
• zotumphukira edema;
• malungo;
• matenda a anorexia;
• maganizo;
• tachycardia;
• alopecia;
• dyspnea;
• redness pa malo jekeseni;
• paresthesia.

contraindications

Mu mankhwala "Diferelin" Pali ena contraindications ntchito. Iwo zokhudzana ndi boma wodwalayo wathanzi, komanso makhalidwe ake payekha thupi. Mwachitsanzo, anthu sangathe kutenga mankhwala ndi timadzi-palokha kansa ya prostate ndi pambuyo kuchotsa machende amayi ali osavomerezeka pa mimba, yoyamwitsa, ndi polycystic n'kuwasanganiza syndrome. Aliyense, popanda yekha, kugwiritsa ntchito mankhwala mosamala "Diferelin" kufooka kwa mafupa ndi hypersensitivity kwa zigawo zake. Ngati zizindikiro zilizonse chowawa, wodwala ayenera yomweyo dokotala.

General ikadzatha ntchito

Monga tanena mankhwala "Diferelin" kumabwezera mmbuyo ulimi wa mahomoni kugonana amuna ndi akazi, potero powapatsa iwo mu mkhalidwe castration yokumba. Mwachionekere, kumiza ngati boma ndi linanena bungwe kwake limodzi ndi maganizo, endocrine-kagayidwe kachakudya ndi neuro-vegetative matenda osiyanasiyana.

Nditamaliza mankhwala ndi mahomoni izi mankhwala obwezeretsedwa, koma pa ndondomeko izi zimakhala zosokoneza wodwalayo irritability, kutopa, kupweteka kwa mutu, thukuta, amamva, maganizo, malungo ndi zizindikiro zina zosasangalatsa. Komabe, miyezi chimodzi ndi theka pambuyo pa mapeto a mankhwala wodwala thanzi ndi sankaganiza. Ndiko kuti, zambiri pambuyo jekeseni otsiriza "Diferelin 11,25 mg wa" muyezo timadzi abwezeretsedwa pambuyo miyezi 4.5, ndi zochita za mankhwala pa ndende ya 3,75 mg wa akumaliza pambuyo miyezi 2.5. Pa nyengo iyi amai ndi abambo ali anapulumutsa ndi kumukonzanso mokwanira ntchito yobereka ndi kugonana ndi libido akubwera kubwerera mwakale.

mimba

Pamene mwana wobala chithandizo "Diferelin" contraindicated. Komabe, mankhwalawa chimagwiritsidwa ntchito kumapangitsanso ovulation. akazi ambiri amatha kukhala pakati pambuyo jekeseni angapo mankhwala, koma mosadziwa, akhalabe makhwalawa "Diferelin". Zotsatira za mankhwala akhoza kukhazikitsa, sikuti kuvulaza mwana wosabadwa: osati zoyambitsa chiopsezo cha padera ndi si abwino chitukuko cha malformations kobadwa nako. Komabe, limagwirira cha zochita za mankhwala pa wamkazi dongosolo ubereki pa mimba amafuna mosamala.

Mankhwala analogues "Diferelin"

Pa msika panopa mankhwala pali mankhwala n'chimodzimodzi umodzi, wochitirana mu kapangidwe kake ali yemweyo yogwira pophika - ndi "Dekapeptil". Komanso, pharmacies angapezeke mankhwala kukhala ndi achire zotsatira monga mankhwala "Diferelin". A kuchita chimodzimodzi thupi amaperekedwa ndi: utsi "Buserelin" lyophilisate "Buserelin Depot", "Zoladex" kapisozi formulations "Eligardt" ndi "Lyukrin Depot".

Reviews

Pali onse ndemanga zabwino ndi zoipa kugwiritsa ntchito mankhwala "Diferelin". Jekeseni wa mankhwala ndi zotsatira zosiyana pa odwala. akazi ambiri ndipo konse olemba zotsatira achire ku kuchiritsa fibroids ndi matenda ena, kudandaula mavuto amene bwino analekerera ndi iwo mu njira zochizira kunenepa, amamva, irritability, kutopa. Pa nthawi yomweyo, odwala onse amavomereza kuti zovuta mayeso mankhwala mankhwala akadali bwino M'mimbamo opaleshoni.

Mankhwalawa kansa ya prostate ndi pathologies ena amuna kudzali ndemanga wosanganiza pa zotsatira za mankhwala "Diferelin". Mtengo wa mankhwala ambiri amaoneka njira zovomerezeka ntchito ndi si zogwira mtima, ndi kuti ntchito bwino ndi chiyani anapeka odes matamando, chifukwa osati amachotsa chotupa wokha, komanso kumatha metastases mu mafupa. Komabe, pali ndemanga zoipa za mankhwala "Diferelin" chifukwa awiri zifukwa: mankhwala osauka ntchito nthawi zina zenizeni, ndipo mavuto amene bwino analekerera ndi odwala ena, nadzawafetsa iwo kusiya mankhwala kapena kwathunthu akugwa kayendedwe wamba a m'moyo.

mitengo

mtengo wa mankhwala "Diferelin" ndi chiyani? Mtengo wa mankhwalawa zimasiyanasiyana malinga zosiyanasiyana ndi, mankhwala unyolo, umene chogulitsidwa, ndi malire pa katundu. Choncho, panopa msika kufunika kwa mbale zisanu ndi ziwiri "Diferelin 0.1 mg wa" ranges ku 2597-3107 rubles. Kwambiri mlingo Pakufunika ndalama yaikulu kwambiri: 1 botolo "Diferelin 3,75 mg," wogula kulipira kuchokera 7632 mpaka 9076 rubles. Mwachibadwa, mankhwala okwera mtengo kwambiri ndi ndende wamkulu. Mmodzi ampoule "Diferelin 11,25 mg wa" zikhoza kugulidwa 18 269-23 100 rubles.

M'malo okwezeka ndi mtengo wa mankhwala "Diferelin". Zida ngati zimenezi mtengo, koma pangano ungakhulupiriridwe chabe dokotala wodziwa, chifukwa iwo ali ndi makhalidwe osiyana kwambiri pharmacological, contraindications ndi zotsatira zake zoyipa.

Pomaliza

Tsopano kuti inu mukudziwa zonse zokhudza "Diferelin" katundu wa mankhwala. Izi mankhwala m'thupi polimbana ndi matenda ambiri, koma zikhoza kwambiri mavuto. Isanayambe chithandizo, wodwala aliyense ayenera kukonzekera chakuti mankhwala amenewa kungakhale kovuta zovuta. Komabe, chiopsezo aliyense ayesedwa wolungama, ngati ilipo ndi thanzi ndipo nthawi zina moyo wa munthu. Choncho musataye ntchito mankhwala "Diferelin" kapena m'malo ndi analogues mtengo. Ndi bwino kuyamba mankhwala ndi njira yabwino kwambiri ndipo potero kuonetsetsa kuti ndi zotsatira zabwino. Khalani wathanzi!