Kashiamu muzikangana - yotakata-sipekitiramu mankhwala

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Mu moyo wa chamoyo zonse kashiamu ayoni kumathandiza m'malo zofunika. Popeza kuti anali calcium, ozama mu maselo amatha mphamvu zonse zhiznenovazhnye njira okhudza maselo ambiri mu chamoyo, mwachitsanzo, kutembenuka ATP mumsasa kapena mapuloteni phosphorylation njira.

Lamulo ayoni kashiamu mu thupi

Kashiamu likulowerera maselo kupyolera mu njira yapadera, imene lalikulu mapuloteni mamolekyulu amene kusinthitsa mwa Kakhungu multilayer maselo. Awa "njira" Inter zina zotere, ndi maselo yeniyeni, yomwe ikuchitika chizindikiritso cha ayoni calcium, popanda akudumphadumpha ndi particles ena.

The otaya ayoni kashiamu mu chamoyo ndi Lamulo zinthu zenizeni amkati amene angakhale monga chiyambi neurogenic ndi kukhala endocrine owayimira monga acetylcholine kapena serotonin.

Mankhwala kuti ndigwire malowedwe a ayoni kashiamu m'zipinda

Studies mankhwala akhoza ziletsa njira kashiamu wa ndimeyi inayamba mu 60s ndipo ikupitirizabe. Kumayambiriro kwa maphunziro awa anali otseguka mankhwala fenilakilamina zotumphukira umene panthawi akhala akufuna ntchito monga kukonzekera koronorasshiryayuschih. Today anatsegula ambiri ndithu lalikulu la zinthu zina, amene amaphatikizidwa mu gulu limodzi, amene anapatsidwa dzina lakuti - kashiamu muzikangana.

Ntchito muzikangana kashiamu

muzikangana kashiamu tsopano ankagwiritsa ntchito zosiyanasiyana za mankhwala, ichi ndi chifukwa chakuti iwo ndi osiyanasiyana lalikulu la kanthu. Choncho, mwachitsanzo, calcium muzikangana zingakhudze m'mnyewa wamtima contractility, atrioventricular conduction ndi ntchito nkusani mfundo.

A kuchita chimodzimodzi ndi aldosterone muzikangana kuti ndigwire ntchito chifukwa madutsidwe aldosterone ake cholandilira, potero kukula kuchuluka kashiamu mu maselo.

M'njira zinthu pathological, monga hypoxia kapena ischemia, amaika kashiamu ayoni amatha kukulitsa njira okhudza maselo ambiri, motero kuchuluka minofu mpweya, tingayambe zotsatira zosiyanasiyana pathological. Pankhaniyi, kashiamu muzikangana ndi zotsatira achire, kuchepetsa ntchito ya ayoni kashiamu mu njira selo lapansi.

muzikangana kashiamu zochizira matenda kugwirizana ndi CAS

ntchito zake zikuluzikulu kashiamu blockers njira lerolino mankhwalawa matenda a mtima. Mankhwala zingakhudze madutsidwe ndi excitability wa mtima, mavuto antianginal, kusintha inatsekeratu magazi ndi kuchepetsa magazi.

Mankhwala amene amakhudza mtima conduction ndi excitability lero ntchito ngati mankhwala antiarrhythmic zinachititsa kuti kusankha osiyana pharmacological gulu (angianginalnye njira).

Muzikangana kwambiri bwanji kupatsidwa zinthu za m'mwazi loitanirana, kuchepetsa coalescence awo ndi zomwe disaggregation cha othandiza magazi kuundana. Mankhwalawa amagwiritsidwa ntchito kuchepetsa magazi kukhuthala nadzawonjezapo pa elasticity wa othandiza magazi kuundana. Kuonjezera mphamvu ya anticoagulant magazi ntchito ndi vitamini K muzikangana kuti asokoneze kutsegula kwa prothrombin kutchinga mapangidwe kuundana Ulimbo.

The sipekitiramu a zochita za mankhwala

The sipekitiramu a zochita za muzikangana kashiamu alidi osiyanasiyana, chifukwa iwo tsopano ntchito osati kwa kusamala mitundu ikuluikulu ya matenda a mtima, komanso mankhwala a mutu waching'alang'ala, mphumu, matenda a makope ubongo. Kashiamu muzikangana mbali yofunika kwambiri pa matenda a matenda a m'maganizo, ntchito pa matenda a khunyu ndi dyskinesia odwala ndi akuchita misala.