Kusowa tulo kungachititse kuti matenda a Alzheimer

Kusowa tulo usiku ndi kukhala pa tsiku daze ndi ... Anthu ambiri akukumana ndi kusonyeza kusowa tulo. Malinga ndi kafukufuku latsopano, osauka khalidwe la kugona ndi usana kugona angathe kuonjezera kudwala matenda a Alzheimer.

Kafukufuku chidwi

anthu 101 tinaitanidwa phunzirolo. Anthu onsewa anali mwaonapo kuwonongeka aliyense chidziwitso. The zaka nkhani anali zaka 63.

Pambuyo kuyesera, otenga mafomu mafunso pankhani ya tulo tawo, aliyense wa iwo anadutsa pa chitsanzo awo a madzimadzi msana. Cholinga cha kuwunika anali kudziwa pamaso pa mipukutuyi mayeso, amene ali ndi zizindikilo za matenda a Alzheimer. Asayansi anazindikira kuti otsika kugona khalidwe ndi usana tulo kugwirizana ndi mitengo kuchuluka cha kuwanda matenda.

Mmene beta-amyloid mu zosayembekezereka ya mipukutuyi mu ubongo

Ngakhale kugwirizana pakati kusagona tulo ndi maganizo si 100% bwino, maphunziro angapo pa nyama aona kuti akagona luso ubongo kupeza poizoni monga beta-amyloid (mapuloteni poizoni) bwino. Zoyambitsa maonekedwe a mipukutuyi mu ubongo wa odwala ndi odwala Alzheimer, ndipo mwina icho chiri chimodzimodzi ndondomeko mmenenso anthu. Chiyambi cha amyloid mu ubongo minofu koyamba kudziwika siteji preclinical za matenda a Alzheimer ndipo amapezeka bwino pamaso maonekedwe a zizindikiro za maganizo.

ophunzira onse a maphunziro anali tinakambirana zinthu chiopsezo cha matenda a Alzheimer. Atatengedwa kupita ku nkhani majini maziko, mbiri banja ndi deta pa APOE jini, amene anagwirizana ndi Mwina wamkulu wa kutha kwa ntchito maganizo. Munthu aliyense anapereka anapeza chiwerengero cha maola tulo, kugona khalidwe ndi tulo masana taonera.

"The ophunzira mu phunziroli anali wokonzeka kulandira ndi lumbar puncture patsogolo kafukufuku mu zimayambitsa matenda a Alzheimer - anati wolemba mkulu Barbara Bendlin sayansi ntchito ya Center Research wa Disease ku Wisconsin. - Analysis wa madzimadzi anatilola kuyang'ana zolembera omwe akugwirizana ndi matenda a Alzheimer monga zolengeza, komanso zizindikiro za kutupa ndi mitsempha kuwonongeka selo ".

Osauka kugona akapsa matenda si milandu onse

Tikumbukenso kuti si onse amene ali ndi mavuto ndi tulo, kukhala matenda a Alzheimer. Barbara Bendlin, amene ndi pulofesa wothandizira wa mankhwala wa pa yunivesite ya Wisconsin School of Medicine, anauza The New York Times: «kusunga magulu a anthu ndipo nthawi zambiri kukondwerera ubale wa tulo osauka ndi zolembera za neurodegeneration. Koma pamene inu muyang'ana pa anthu, ayi konse noticeable pamaso pa tulo. "

Zatsopano pa mbewa

Izi kuphunzira atsopano ndi kupitiriza maphunziro kale sayansi ankatanthauza kuti kutanganidwa kugona kungakhale chifukwa cha maganizo. Ofufuza ena apeza limasonyeza pakati pa matenda aakulu kugona ndi chitukuko cha mipukutuyi amyloid. Studies in mbewa anasonyeza kuti nyama amene anagona, mlingo wa beta-amyloid anachepetsedwa. Lopumula bwino kukonza ubongo wa mbewa kwa poizoni.

Bendlin ndi anzake ogwira kusunga anthu pa ngozi ya matenda a Alzheimer. nkhani tikambirana mu zasayansi tulo, pamene mayesero cholinga kuti zizichitidwa.

Kuteteza kusintha kulikonse tulo khalidwe chitukuko cha matenda?

"Ngati likukhalira kulowererapo, amene adzachotsa chikhalidwe pathological ngati tulo, kutsogolera chakuti mu ubongo adzakhala waikamo zochepa amyloid, izo amathandiza amphamvu kukhazikitsa miyezo choipa pamaso pa anthu amayamba kusonyeza kuchepa chidziwitso kugwirizana ndi matenda a Alzheimer "- Bendlin anati.

Bendlin ananenanso kuti pamaso akafunsa katswiriyu kuti adakulemberani m'tulo mapiritsi, muyenera kudziwa chimodzimodzi ngati mankhwala kuthetsa kugona pa chikoka cha amyloid. Chotsatira adzakhala kupitiriza kupereka mogwirizana ndi chizindikiro ichi.