Mankhwala "Algezir Chotambala": malangizo ntchito, maonekedwe, zikuchokera ndi ndemanga

The "Chotambala Algezir" Madokotala amakonda kulemba odwala posachedwapa. Malangizo kwa njira imeneyi ndi m'malo nkhani ndipo amafotokoza mbali tanthauzo lake osiyana- siyana odwala, koma ali kutali ndi kukhala mudziwe wathunthu okhudza mmene thupi kumatanthauza.

mankhwala

Monga mbali ya njira - NSAIDs, amene ndilochokera naftilpropionovoy acid. Mu ndondomeko ya kulandira mankhwala ali wotsutsa-yotupa, antipyretic ndi kanthu analgesic, monga kawirikawiri umboni ndi ndemanga "Algezir Chotambala". Guide to pamalowo Limanenanso kuti zinthu zimenezi.

Limagwirira cha zochita za mankhwala ndi mwachindunji ndi chopinga a Cox enzyme apadera kuti maximizes prostaglandidov ziletsa kaphatikizidwe wa asidi arachidonic. Komanso, izi zikutanthauza amapereka chopinga wa kupatsidwa zinthu za m'mwazi loitanirana.

mwapadera ziperekedwe chakuti m'kati kutenga mankhwala yafupika ululu, kuphatikizapo kupweteka kwa m'malo olumikizirana mafupa mu poyenda ndi pa mpumulo. Mu ndondomeko ya kulandira maola olowa kutupa, mmawa stiffness, kuwonjezera osiyanasiyana zoyenda, lomwe limati pafupifupi munthu aliyense amene anasiya ndemanga za «Algezir Chotambala" njira. Malangizo mauthenga amenewa mulinso, nthawi yomweyo anati mfundo imene tingati odana ndi yotupa chingapezeke mwa kumapeto kwa sabata loyamba la mankhwala yogwira.

Pharmacokinetics

Kenako, phwando chida mu naproxen akuyamba mofulumira odzipereka kwa mundawo m'mimba. Chizindikiro C _Max mu plasma liyamba anati kale maola 1-4 pambuyo ingestion. Tikumbukenso kuti ntchito munthawi yomweyo mankhwala ndi chakudya amachedwetsa mlingo wa mayamwidwe, koma sanali kuchepetsa mlingo wonse wa mayamwidwe. Naproxen losiyana mayamwidwe mokwanira bwino pa nkhani ya utsogoleli thumbo, koma mu nkhani iyi pali zambiri pang'onopang'ono mayamwidwe poyerekezera ndi njira m'kamwa.

Pa woipa akangofika mchitidwe yogwira chimamanga zonsezo plasma ndi pafupifupi 100%. Anthu ambiri naproxen mu kuwonjezeka plasma mofanana pa ntchito Mlingo mpaka 500 mg, koma pa mlingo waukulu pali ponso chilolezo, amene amayamba ndi machulukitsidwe lathunthu la mapuloteni plasma.

Naproxen diffuses mu madzimadzi synovial.

T _1/2 pafupifupi 13 maola. Pafupifupi 95% ya kuchuluka okwana mlingo pamapeto pake excreted mu mkodzo mu boma unmodified, 6-O-ndiponso conjugates zosiyanasiyana dezmetilnaproksena. China chirichonse posachedwapa atakhala excreted mu chimbudzi.

mlingo

Dziwani kuti analimbikitsa Mlingo munthu za kukhazikitsidwa malinga ndi kukula kwa matenda wodwalayo. Ndi mankhwala "Algezir Chotambala" malangizo limasonyeza kuti akulimbikitsidwa akulu kutenga Mlingo wa 0.5-1 ga patsiku pa mlingo awiri, pamene ezhednevnayadoza chifukwa tikukonza mankhwala wabwinobwino ayenera kukhala pafupi 500 mg.

The pazipita zotheka tsiku mlingo wa 1,75 ga

Mlingo wa ana

Ngati mankhwala ikuchitika odwala zaka zapakati pa chaka 1 mpaka zaka 5, mu nkhani imene ayenera kugwiritsidwa ntchito pa 2.5-5 mg wa pa makilogalamu pa tsiku kwa 1-3 phwando la tsiku, pazipita nkotheka mankhwala Pankhaniyi kungakhale 14 masiku. Mankhwalawa zaumbanda nyamakazi ana akuluakulu kuposa zaka 5, mlingo tsiku chili ndi mg ndi 10 pa kg.

mogwirizana mankhwala amatanthauza "Algezir Chotambala"

Malangizo ntchito ndi chakuti, mwina kuti zikuwononga zimakhudza mayamwidwe naproxen, chimene chiri chofunika kwambiri mankhwala ngati ntchito imodzi ndi Mankhwalawa ayenera kumwedwa, monga zotayidwa, magnesium, ndi sodium wochuluka hydrogencarbonate.

Ngati chida ntchito ndi anticoagulants mozungulira, pakhoza kupezeka zazing'ono amveke kanthu mankhwala kuti taonera kale mu njira ya maphunziro apadera matenda.

Komanso pa kafukufuku izo anali kuphunzira zotsatira za ntchito munthawi yomweyo wa amoxicillin mankhwala, kotero kuti zinthu zina anayamba kukhala syndrome nephrotic. Ngati "Algezir Chotambala" anagwiritsidwa ntchito ndi asidi acetylsalicylic, zina yafupika ndende okwana naproxen mu madzi a m'magazi.

mbali zina za mogwirizana ndi

Komanso, Dziwani zinthu zina zimene yofotokozedwapo mankhwala "Algezir Chotambala" (mapiritsi) Malangizo ntchito:

• pamene ntchito amapereka kusintha zina pharmacokinetic magawo ntchito diazepam;
• Ngati chida umagwiritsidwa ntchito imodzi ndi tiyi kapena khofi, naproxen kungathandize patsogolo;
• ntchito pamodzi lifiyamu carbonate amatipatsa kuthekera kuwonjezeka lifiyamu ndende mu madzi a m'magazi;
• Mothandizana ndi methotrexate kumawonjezera kawopsedwe wa thunthu;
• pamene "Algezir Chotambala" ntchito pamodzi ndi probenecid amachepetsa ndende okwana naproxen mu madzi a m'magazi;
• ntchito munthawi yomweyo amalola salicylamide patsogolo ntchito ya thunthu.

Pali malipoti osonyeza kuti ngati chida ntchito molumikizana ndi morphine, pamapeto, zimenezi zingayambitse chitukuko cha myoclonus. Komanso, pamene akugwiritsa ntchito prednisone anati kuwonjezeka kwambiri mlingo wa ndende ya thunthu mu madzi a m'magazi. Komanso, monga taonera ntchito payokha munthawi yomweyo furosemide, amene amathandiza kuti kuchepetsa zotsatira diuretic wa thunthu. Izi taonera pa malo monga mankhwala "Algezir Chotambala" ndemanga. Malangizo Ikufotokozanso Mbali imeneyi ya mankhwala.

Mimba ndi mkaka wa m'mawere

kusamala kwambiri akulimbikitsidwa kugwiritsa ntchito mankhwala amayi oyembekezera kapena lactating, makamaka izi zikugwira ntchito kwa anthu amene panopa amakhala mu trimester kapena wachitatu. Mfundo lonse pano pambuyo kumutenga naproxen mankhwala umayamba mkatikati mwa placental chotchinga, ndipo kenako anamasulidwa zedi yaing'ono mkaka wa m'mawere.

zotsatira zoyipazi

Ndi anatchula zotsatira ochepa mbali zimene yofotokozedwapo mankhwala "Algezir Chotambala" malangizo Buku ofunika. Titsimikizidwa Pankhaniyi zilipo pa magulu osiyana a mabungwe:

• Dongosolo m'mimba. Pa phwando akhoza kupezeka kusanza, kusapeza mu epigastrium lapansi. Nthawi zina kuwonetseredwa erosive ndi zotupa anam'peza pa mundawo m'mimba, komanso zosiyanasiyana nthenda chiwindi ntchito ndi magazi.
• Chapakati mantha dongosolo. Pamene inu ntchito ena odwala kumeneko tulo, mutu, ndi liwiro mosiyanasiyana psychomotor liwiro. Nthawi zina kwambiri, kugwiritsa ntchito chida ichi, pali matenda osiyanasiyana kumva, umboni ndi mankhwala "Algezir Chotambala" malangizo Buku. Mkota sakufotokoza mwatsatanetsatane ntchito bokosi limeneli.
• hematopoietic dongosolo. Kwambiri mocheperapo ntchito mankhwala kumabweretsa zosayembekezereka wa granulocytopenia ndi thrombocytopenia ndi hemolytic kapena aplastic magazi m'thupi.
• Kupuma dongosolo. Nthawi zina angathe chibayo eosinophilic.
• Dongosolo mkodzo. Nthawi zina, angayambitse chisokonezo zosiyanasiyana za ntchito impso.
• thupi lawo siligwirizana. Mu gulu linalake odwala mu njira ya zofufuza anati urticaria, tizilonda ta pakhungu, angioedema, zomwe ndi zofala, thupi lawo siligwirizana ndi zigawo zosiyanasiyana zimene amapanga mankhwala, monga tanenera "Chotambala Algezir" malangizo Buku. Chithandizo Pankhaniyi sitingazimvetse inaimitsidwa.

Komanso mwapadera woyeneradi mfundo zimene zinachitikira ntchito thumbo, pali chiopsezo secretions mucous ku wochepa magazi kapena pakutchulidwa wa defecation chopweteka.

Pamene ntchito?

Mu zaka zingapo zapitazi, madokotala amakono kaŵirikaŵiri zokwanira atayamba mankhwala odwala awo chida ichi mankhwalawa zosiyanasiyana matenda, kuphatikizapo anthu amene anafotokozedwa "Chotambala Algezir" malangizo Buku. Mtengo wa mankhwala alipo pafupifupi aliyense, mogwirizana ndi zomwe ndi zambiri zotchulidwa m'malo ambiri ndalama zambiri zofanana.

Kwenikweni, Dziwani ndi matenda zofunika zochepa, chithandizo umene ntchito ndi achangu kwambiri:

• nyamakazi;
• nyamakazi;
• ankylosing spondylitis;
• pachimake gout;
• articular syndrome;
• neuralgia;
• myalgia;
• kupweteka msana;
• zoopsa kutupa zimakhala zofewa kapena dongosolo minofu ndi mafupa.

Komanso, "Algezir Chotambala" Nthawi zambiri zikuchitika monga wothandiza mu mankhwala a matenda osiyanasiyana opatsirana ndi yotupa wa ENT, dysmenorrhea chachikulu, adnexitis, komanso mano ndi mutu.

contraindications

Pali zina zimene chida ichi sayenera kugwiritsidwa ntchito, ndipo umatiuza za mankhwala "Algezir Chotambala" malangizo ntchito (kulongosola). Reviews Madokotala kaŵirikaŵiri amati mankhwala ali osavomerezeka ndi zinthu zotsatirazi:

• "Aspirin wa ku";
• mitundu yonse ya erosive ndi zotupa anam'peza kapepala kakuti m'mimba;
• bwino anasonyeza matenda mu ntchito aimpso;
• dongosolo hemodyscrasia;
• bwino anasonyeza matenda mu ntchito chiwindi;
• kwambiri kudziwa naproxen ndi zinthu zina m'gulu zikuchokera mankhwala.

Mwa zina, ntchito chida ichi ali osavomerezeka chifukwa ana osakwana zaka chaka chimodzi, monga umboni ndi mankhwala "Algezir Chotambala" malangizo. Mtengo wa chida ichi ndi 85-90 rubles. mapiritsi 10.

Kusamala

mosamala kwambiri ayenera chida ntchito pa matenda a matenda osiyanasiyana a impso ndi chiwindi, kapepala kakuti m'mimba mu mbiri, komanso kulephera mtima, matenda oopsa kapena pamaso pa zizindikiro dyspeptic. Makamaka, ayenera mokakamizidwa kukaonana ndi dokotala anu ngati n'zotheka ntchito mankhwala pambuyo zikunena lalikulu opaleshoni.

Mu mankhwala ayenera kukhala nawo ulamuliro dongosolo la ntchito kwa impso ndi chiwindi, komanso zotumphukira magazi chithunzi. Ngati ndi kotheka, kudziwa mlingo wa ndende ya 17 ketosteroids kulandira naproxen kwenikweni muyenera kuletsa maola wina 48 ticite ankayembekezera phunzirolo.

mwapadera ziperekedwe chakuti kutenga mankhwala kumakhudzanso kuthekera kuyendetsa galimoto zoyendera ndi kasamalidwe ka njira zosiyanasiyana. Pa nkhani imeneyi, ndi bwino kuchepetsa amapewera ntchito iliyonse zikanavulaza mwachindunji zokhudzana ndi kufunika ndende ndi kuchuluka liwiro mosiyanasiyana psychomotor onena "Algezir Chotambala". pa ntchito malangizo yokonza payokha limatsindika mfundo imeneyi.