Mankhwala "Trifas": malangizo ntchito, analogs ndi ndemanga

zinthu Pathological mu oopsa zofunikira ndipo congestive kulephera mtima ali limodzi ndi minofu kutupa ndi ziwalo za m'kati zofewa, ndi owopsa kwa anthu. Kuchotsa madzimadzi owonjezera m'thupi ntchito okodzetsa omwe amaonjezera buku la mkodzo linanena bungwe ndi mchere. mankhwala amodzi otero ndi diuretic "Trifas".

Kufotokozera lokonzekera

The zikuchokera ali ndi yogwira chigawo mankhwala torasemide, amene akutumikira monga asidi maziko sulfamonlantranilovaya. Nkhanizi amatanthauza saluretic, kuti akhale ndi zotsatira ochepetsera pa reabsorption wa ayoni soda ndi chlorine mu impso.

Fomu kumasulidwa

Pali zosintha zingapo "Trifas" chiphunzitso, malangizo ntchito olimba ndi mlingo madzi ndipamene yake. Aliyense mwa zinthu zimenezi zafotokozedwa katundu physico-mankhwala a miyala ndi mavutowo.

Piritsi yokonza njira zilipo pansi pa tradename "Trifas 10" ndi mlingo wa 10 mg wa torasemide ndi "Trifas AKOR» torasemide ndi mlingo wa 5 mg. Analongosola anasonyeza kuti mapale woyera ndi kuzungulira ndi Valium chifukwa kugawikana pa mbali imodzi Mlingo zikuluzikulu.

The madzi mawonekedwe lokonzekera "Trifas" Buku limafotokoza monga njira jekeseni mu mlingo wa torasemide 10 mg pa 2 ml ndi 20 mg wa mu 4 ml, njira yothetsera kulowetsedwa mu mlingo wa 200 mg pa 20 ml ya madzi. Malinga ndi kufotokoza ndi colorless mandala njira imene pafupifupi palibe kulolerana wa particles.

Kufotokozera za zikuchokera miyala

Pakuti piritsi limodzi "Trifas" kukonzekera malangizo akupereka zikuchokera: zili yogwira zikuluzikulu za torasemide mu kuchuluka kwa 10 mg kapena 5 mg, komanso ali wofooka zinthu kupereka kukonza dongosolo piritsi, solubility ake, ndi chitetezo pa nthawi mwachindunji. Zikuphatikizapo mkaka shuga, wowuma chimanga, magnesium stearate ndi anhydrous Aerosil.

Kufotokozera njira zikuchokera

Mbale ndi 2 ml ya torasemide ndi sodium m'gulu jekeseni mu kuchuluka kwa 10.631 mg, amene ali ofanana ndi 10 mg wa torasemide.

Mbale ndi 4 ml ya njira ya torasemide lili ndi sodium jekeseni mu kuchuluka kwa 21,262 mg ndi amene ali ofanana ndi 20 mg wa torasemide.

Mbale ndi 20 ml ya yothetsera kwa torasemide kulowetsedwa kuphatikiza ndi sodium mu kuchuluka kwa 212,62 mg, lomwe ndi lofanana mg wa 200 torasemide.

Kuwonjezera pa pophika yogwira, kotero mu madzi injectable kochepa hydroxide sodium, polyethylene glycol 400, trometamol.

limagwirira kanthu

Pokonzekera "Trifas 10" malangizo ntchito lili za kumanga mu lumen wa nephron torasemide ukubwera ndi Na-K-CL-kotransportorom omwe ndi puloteni ili mu chipolopolo pamwamba pa khungu, zikubweretsa yimitsira wa ion zoyendera K ^+, Na ^{+ ndipo} cl ^- kudzera lumen ritsa.

kanthu Diuretic miyala akufotokozera pambuyo ola 3 ndipo amalimbikira pafupifupi 12 maola. Mankhwala ntchito ngakhale pamene palibe zotsatira za okodzetsa zina monga thiazide. Ndi kuchepetsa okwana zotumphukira mitsempha kukana ndi aligning bwino electrolytes ndi kumanga ufulu kashiamu ayoni mu minofu yosalala khoma mtsempha wamagazi, ndi medicament Sachita magazi.

Kuti amachitira mankhwala

Miyala "Trifas" ntchito mankhwala opezeka oopsa zofunika kwa mankhwala ndi kupewa njira odana ndi yotupa kapena effusions m'munsili mtima kulephera.

Njira yothetsera makonzedwe mtsempha pamene kutumikiridwa edema m'mapapo mwanga, ndi njira kulowetsedwa ntchito odwala ndi wotsikirapo ntchito aimpso, pamene creatinine chilolezo mlingo wa zosakwana 20 ml ya mphindi.

Kodi mapiritsi a

Mu ntchito zofunika mankhwala oopsa "Trifas" malangizo Buku akuonetsa kuti piritsi kugawidwa m'magulu anayi ndi kuyamba mankhwala ndi mlingo tsiku la 2.5 mg wa torasemide. kuchepetsa kuthamanga sadzafika nthawi yomweyo, ndi mwa sabata loyamba, zotsatira pazipita amapezeka pasanafike masabata 12. Popeza zimakhudzanso antihypertensive itapita miyezi itatu mlingo tsiku "Trifas" chiphunzitso, malangizo ntchito limalangiza bisect mapiritsi, theka lililonse ngati lili 5 mg wa torasemide.

Pamene matenda oopsa pamene akalozera wa kuthamanga diastolic kuposa 115 mmHg, ndi ntchito yochepa aimpso mwina kumasonyeza zina kanthu antihypertensive.

Edema kapena effusion patsiku 5 mg torasemide kapena ½ wa piritsi "Trifas 10", malangizo ntchito lili ndi mfundo za kufunika kuwonjezera mlingo 20 mg wa torasemide ndi zopanda phindu lolingana magome awiri lokonzekera. Kumwa mankhwala m'mawa, popanda kuphwanya umphumphu ndi ena madzi. Chakudya wambiri alibe zotsatira pa digestibility miyala, ndi nthawi ya mankhwala amagwirizana ndi chikhalidwe ndi zochita za matenda.

Kodi kugwiritsa ntchito njira jekeseni

Zochizira mankhwala wamkulu "Trifas" malangizo Buku zikuphatikizapo kuimilidwa ndi ntchito limodzi tsiku mlingo wa 2 ml, lomwe lili ndi 10 mg wa torasemide. Ngati ndi kotheka, mlingo tsiku linawonjezeka 4 ml, Chofanana 20 mg wa mankhwala yogwira. Pamene kulephera kwenikweni ntchito mlingo tsiku la 8 ml, lofanana mg wa 40 wa torasemide, koma salinso kuposa masiku 3.

Chikhalidwe cha pachimake m'mapapo mwanga edema kuthetsa oyamba ampouled 4 ml ya yothetsera dosed pa 10 mg wa torasemide. Mu nkhani ya mogwira osakwanira pa theka la ola ikuchitika reintroduction 4 ml ya yothetsera mankhwala. Osafunika owonjezera mlingo kwa 100 mg pa tsiku la torasemide womwe ndi 20 ml ya yothetsera "Trifas".

Kodi kugwiritsa ntchito njira yothetsera kulowetsedwa

Buku anafotokoza ntchito ndi kulowetsedwa mawonekedwe akuluakulu. alili ndi kulephera impso Mzimuyo mlingo. Ntchito kuyamba ndi mlingo tsiku la 5 ml, munali 50 mg wa torasemide. Ngati mankhwalawa sakhala kumapangitsanso excretion wa mkodzo, chinawonjezeka ndi 10 ml. Chovomerezeka pazipita achulutse 20 ml ya kulowetsedwa njira "Trifasa 200" kukonzekera lomwe lili 200 mg wa torasemide. Mobwerezabwereza makonzedwe mtsempha ikuchitika pambuyo ola 1 ntchito Perfusor kuwongola mlingo kulowetsedwa wa 0.4 ml ya mphindi. Pakuti mayiko, 1 vial wasukuluka 500, 250, 125 kapena 30 ml ya 0,9% ndi sodium njira mankhwala enaake kapena 5% shuga njira. Chotero osakaniza ayenera kugwiritsidwa ntchito yomweyo, otsala unatsanuliridwa.

chithandizo mtsempha sayenera upambana sabata imodzi, makamaka mwamsanga kupita pa kumwa mankhwala ngati kungatheke.

Features ya ntchito

Yaitali ntchito mankhwala "Trifas" malangizo ntchito limafotokoza mkhalidwe kuti amafuna polojekiti nthawi zonse muyezo wa electrolytes, makamaka ayoni potaziyamu mu seramu magazi. Shuga, creatinine, asidi uric , ndi mafuta - magawo onsewa amafuna miyezo kuti mwamsanga kuti chitukuko cha matenda a shuga. Pa mankhwala, tiyenera kulamulira magawo magazi wodwalayo.

Pa mimba ndi mkaka wa m'mawere ndi bwino kugwiritsa ntchito mankhwala, kuyambira deta zokhudza chitetezo cha torasemide kwa mwana kumeneko.

Zochita za mankhwala akhoza kuchepetsa ntchito ya munthu galimoto galimoto ndi njira zina zimene zimafuna chisamaliro. Musati kuphatikiza ndi mowa.

Mankhwalawa ndi contraindicated

Osati aliyense akhoza kutenga mankhwala "Trifas" malangizo Buku likutchula zinthu zimene mankhwala ali contraindicated.

Musagwiritse ntchito:

• hypersensitivity kuti torasemide ndi ena ofanana m'mbuyomu;
• hypotension;
• zoopsa aimpso;
• mu anuria;
• ndi limaphwanya kwambiri a chiwindi, kuphatikizapo chikomokere kapena Prec;
• voliyumu amachepetsa kusuntha magazi;
• pansi yafupika soda ndi zili potaziyamu mwazi;
• ndi mkhutu pokodza chifukwa Prostatic kukulitsa;
• ndi muyeso oxalate mafunsidwe mu malo;
• pa hyperexcitability conduction ndi minofu mtima;
• Pamene kuyan'anila za bwino asidi-m'munsi;
• magazi m'thupi ndi otsika kupatsidwa zinthu za m'mwazi kuwerenga;
• matenda a impso;
• ana osaposera zaka 12 zakubadwa.

sequela osafunika

Mndandanda wa zotsatira zoyipa za mankhwala monga "Trifas" malangizo. Umboni kunena za pafupipafupi zotsatira zina chokhwima.

Pa dongosolo mtima wa mankhwala amachita kuphwanya bwino madzi-electrolyte, zikubweretsa hypovolemia, hypokalemia, hyponatremia, alkalosis, mutu, chizungulire, kutopa, khunyu, minofu minofu, ndi amphamvu mkodzo excretion hypotension, fogging kutsitsimuka, thrombosis, mtima ndi oziziritsa ischemia, arrhythmias mtima, angina pectoris, pachimake m'mnyewa wamtima minofu mtima, kukomoka.

M'mimba torasemide dongosolo ukugwira ndi chiwonetsero cha kudzimbidwa, kusowa kufunika kwa chakudya, nseru, kusanza, kupweteka m'mimba, kutsekula m'mimba.

Odwala matenda pokodza kugwirizana ndi hypertrophy Prostatic, ndi wolimba mapangidwe mkodzo posungira komanso kumwetsa ake anatambasula mpanda wa chikhodzodzo.

Zikoka pa kagayidwe mankhwala, chamankhwala mu madzi a m'magazi uric asidi, shuga, triglycerides ndi mafuta anayamba kumveka bwino, amene kumawonjezera maganizo awo.

Atadziŵa chiwindi achuluke wokhutira wa michere, mwachitsanzo, Popanga madzi a gamma-glutamyl transpeptidase.

Mu zochita za mankhwala mu magazi amachepetsa chiwerengero cha kupatsidwa zinthu za m'mwazi, erythrocyte ndi leukocyte maselo.

mavuto kwa zochita za torasemide imakhudzana ndi kuchuluka tilinazo chamoyo, amene anaonetsa kuyabwa zidzolo, photosensitivity. Nthawi zina, mwina kukhala ndi chikhalidwe cha mantha anaphylactic ndi utsogoleli wa njira mtsempha, chimene chimafuna munthu amene mwamsanga.

analogs

Wopanga "Trifas" pachiyambi mankhwala ndi kampani German, "Berlin-Chemie Menarini Gulu AG" popanga madzi ndi olimba mtundu wa mankhwala. msika Russian mankhwala angapezeke zipangizo generic, amene ali torasemide. Onsewo ali ndi katundu diuretic, limagwirira womwewo wa kanthu ndi ofanana zosiyanasiyana chokhwima chifukwa pophika yogwira.

Kukonzekera "Trifas" analogues amatuluka mu mawonekedwe a mapiritsi ntchito m'kamwa, kapena mu mawonekedwe a njira kwa jekeseni ndi infusions.

lofanana ndi mankhwala "Diuver" chopangidwa ndi Chikolowesha tsopano "Pliva Hrvatska doo". Lili miyala mlingo mankhwala a mg wa 5 ndi 10 torasemide.

German mnzake - mankhwala "Sandoz Torasemide" kupanga kampani "Salyutas Pharma GmbH". Izo zinabala mu mawonekedwe a mapiritsi zili a torasemide 200 mg, 100 mg, 50 mg, 20 mg, 10 mg, 5 mg ndi 2.5 mg.

Miyala "Britamor" chosunga-kumasulidwa opangidwa ndi Spanish kampani "Ferrer Mayiko SA." analogi lili 5 mg ndi 10 mg wa torasemide.

Kukonzekera "Toradiv" Chiyukireniya kampani "Farmeks magulu Ltd." zilipo mapiritsi a 5 mg, 10 mg ndi torasemide mu njira jekeseni 5 mg wa torasemide mu 2 ml kapena 4 mg wa madzi.

Reviews

mfundo zothandiza odwala pa mankhwala lili "Trifas" malangizo Buku. Reviews odwala kulandira chida, umboni wa mphamvu ya kanthu mankhwala edema. Daily kudya a torasemide kumathandiza kuchepetsa zotsatira za madzimadzi owonjezera mu myocardium kwa matenda a mtima. Ndi mankhwalawa odwala zonse mayeso kuti aone zotsatira za mankhwala m'thupi.

Pa mankhwala mankhwala "Trifas 10" Buku limafotokoza ndemanga zabwino kuposa mawu negative. Zotsatira osafunika zimachitika kawirikawiri, koma odwala ambiri, mutawerenga "Anachita Atamva Kulanga" gawo, mantha kutenga mankhwala. Ndipo pachabe, mavuto sayenera zimachitika, koma torasemide kuthetsa kutupa, kuti mupewe madzimadzi owonjezera ndi kuchepetsa magazi. Kuchepetsa kuchuluka kwa madzimadzi zidzathandiza kuti matenda ndondomeko zonse zofunika, muyezo madzi mchere ndi kusintha kwa mtima ndi matenda a mtima.

Pali ndemanga za kupanda mankhwala mu kutupa kwa thupi. Zikatero, dokotala ayenera kusankha chithandizo choyenera ndi zochita za medicaments ngati, koma osati munali torasemide.