Mapuloteni mu mkodzo. zifukwa kukhala osiyanasiyana

Avereji ya mapuloteni okhutira mu mkodzo - ndi kukhalapo kwa seramu mapuloteni nusu, amene umasefedweramo mpanda wa capillaries mu impso ndi. Mwachibadwa, mlingo sayenera upambana 0,002 g / L, ngati inu kubwereka pafunika kumasanthula m'mawa. Masana, 50-150 mg wa mapuloteni mu mkodzo - ndi ponseponse. Koma pamalo okwera ndi okwera mapuloteni mu mkodzo, chifukwa zolakwika ziyenera anafufuza kuchipatala, makamaka ngati mapuloteni ndi wokwezeka pa amayi apakati.

Limagwirira kwa ndondomekoyi, limene kuwonjezeka kuchuluka kwa mapuloteni, ndi opatsirana impso chapansi Kakhungu, m'malo zovuta. Iwo nawo hyaluronidase. enzyme ichi, kuwonjezera pa zinthu zina, zimafunika mucopolysaccharides ku seramu. Kuwonjezera zochita zake timapitiriza permeability makoma capillary ndi Kakhungu permeability, amene wayamba pochitika mapuloteni molekyulu.

Pamene mapuloteni mu mkodzo, zimayambitsa zingakhale zoona (impso) ndi wabodza (extrarenal). Choonadi kapena Bodza la matenda, amayanjana ake kuti ndondomeko zosakhalitsa kapena aakulu akhoza chilichonse koma madokotala.

N'chifukwa chiyani mapuloteni mu mkodzo

Maziko synthesizing zimapanga thupi - ndi mfundo chibadwa. Lilili mu majini anthu mu maonekedwe yosiyanasiyana. Zovuta zoyendera unyolo, kaphatikizidwe, ndi kulandirana ndondomeko yeniyeni ndondomeko izi zimabweretsa kukhalapo ndi oyenera ntchito zimapanga thupi. Nenani pa limodzi la magawo a unyolo zovuta za masinthidwe motsatizana mapuloteni mu mphamvu amene nthawi ndi kulinganiza ntchito yawo, ndipo kodi zimenezi zikubweretsa amapezeka mu mapuloteni mkodzo.

Chifukwa chophwanya amenewa akhoza zimachitika zinthu transiently kapena stably chifukwa cha matenda a ntchito mu thupi. Ndi kosatheka kupereka yankho zochuluka funso lakuti n'chifukwa chiyani mapuloteni mu mkodzo, popanda kuchititsa Kafukufuku mabuku.

Kuonjezera misinkhu mapuloteni zingachititse matenda a makope aimpso:

• anomalies mu chitukuko aimpso mtsempha;
• kusintha chifukwa zotsatira poizoni pa makoma a capillaries mu impso ndi;
• kusintha atamwa mankhwala (kumwa kapena kuti simungathe kuvomereza);
• kuyan'anila mu ntchito ya tubules a impso;
• cholowa ndiponso kobadwa nako matenda.

Ngati nthawi yaitali pali mapuloteni mu mkodzo, zifukwa angakhale matenda osiyanasiyana m'thupi monga dongosolo m'mimba matenda, kuchepa magazi kwambiri, zotsatira za amayaka, kuvulala, kukhudzana ndi ozizira, thukuta, thupi kapena zochitika maziko lokoma. Pankhaniyi, matenda ndi mawonekedwe osakhalitsa, pamodzi ndi kuwonongedwa kwa zifukwa kusiya zomanga thupi kuchokera ku mkodzo.

Permanent (kapena yaitali) kukhalapo kwa mapuloteni mu mkodzo (proteinuria) limanena za matenda a impso ndi zizindikiro zina simuli pano.

zomwe zingatichititse mapuloteni mu mkodzo

• matenda glomerulonephritis;
• glomerulosclerosis chifukwa shuga;
• mu thrombosis aimpso mtima;
• kukhalapo kwa impso congestive;
• miyala impso ndi matenda ena.

Matendawa ndi mankhwala

mapuloteni mu mkodzo imatengedwa linalake wokhutira osati oposa 50 - 150 mg / tsiku. Matenda kuchuluka kwa mapuloteni n'kosavuta. Childs, izi wapezeka ndi kudutsa mkodzo. Masana icho kukodza pa njira inayake. kuwunika linabwerezedwa kupewa chinthu chodabwitsa kuti akhoza kusintha chitsanzo cha anasonkhana.

Pofuna kupewa ngozi pa mayesero nthawi, penyani ukhondo wa ziwiya ndi kusamba bwinobwino akumaliseche. Kuwonjezera mayesero muyezo mkodzo mwina kuchitikira elekitironi wamamamayikirosikopu a impso, amene amathandiza Yang'anani kuyan'anila za chapansi Kakhungu, kuchuluka kwa chiwerengero chake pores ndi kukula.

Makamaka kuyang'anira mosamala mlingo wa mapuloteni mu mkodzo wa amayi apakati, kuyambira ntchito aimpso ndi kumva mwa chiberekero kukula ndi kuonjezera katundu thupi lonse ndi impso makamaka. Wakudziko yafupika ndipo sayenera kuposa 0,14 g / L (akusowekapo zofufuza).

Chithandizo cha matenda kuipidwa zogwirizana ndi mkhutu aimpso (kapena zina matenda anapezeka ndi madokotala) akhoza kuchitika kokha kuchipatala.