"Nalbuphine": malangizo, maonekedwe, zikuchokera, ndemanga

Zimawawa ... zimawawa ... Palibe munthu amene si mawu awa. Pamene tili umapweteka, mavuto onse ena zokha mu maziko. Wofunika kwambiri ndiponso Chofunika panthawi ino - kuti azunzike mbisoweka.

Modern Pharmacy ndi wokonzeka kupereka ogula ndi kufufuza yaikulu mankhwala mankhwala ochititsa ndi mfundo zosankha zake. mankhwala china "nalbuphine." Malangizo nthawi monga agonist ndi opioid cholandilira antagonist, ndi chomwa mankhwalawa analgesic, m'gulu mndandanda wa mndandanda chachitatu cha mankhwala chomwa mankhwalawa.

Kapangidwe pharmacodynamics

Waukulu yogwira pophika "Nalbuphine" ndi nalbuphine hydrochloride. The mankhwala ndi analgesic opioid gulu (mankhwala kupereka chikoka pa thupi, ofanana ndi zochita za Opium). Mfundo kanthu za mankhwala "nalbuphine" malangizo ntchito ndi izi: waukulu yogwira pophika kumabwezera mmbuyo kufala kwa zikhumbo ululu pakati manyuroni mu wamanjenje dongosolo. Mankhwala kumapangitsa mbali apamwamba a ubongo, potero kusintha maganizo maganizo a ululu.

Zotsatira "Nalbuphine" pa thupi la munthu angafanane ndi zotsatira za "Morphine". Nalbuphine hydrochloride kumapangitsa pakatikati kusanza, akhoza kupondereza bongo wabwino, kumakhudza sedative. Mankhwala limaleka malo kupuma, koma pamlingo n'chochepa kwambiri kusiyana ndi "Morphine", "Promedol" kapena "Fentanyl".

mawonekedwe kumasulidwa ndi mlingo kamwedwe

Opanga kupereka makasitomala awo ndi mankhwala Mbale "nalbuphine 10" ndi "20 nalbuphine." Aliyense ampoule - 1 ml ya medicament. Woyamba ( "nalbuphine 10") ankanyamula mu paketi Mbale 10, ndipo chachiwiri - kwa 5. "Nalbuphine" (njira) malangizo ntchito, ogwira ntchito kwenikweni amalangiza anaika chiwembu mosamalitsa munthu, malingana ndi kulemera kwa thupi, kukula kwa zowawa pansiyi matenda.

The medicament akhoza kutumikiridwa m'nsinga, intramuscularly kapena subcutaneously. A mlingo umodzi kwa munthu wamkulu lingayambire pakukhala 100 .mu.g kwa 1 mg pa kulemera makilogalamu thupi. Mlingo koyamba mwana - si zoposa 300 ga pa makilogalamu 1 thupi. Pafupipafupi ntchito medicament amadalira okwana chithunzi matenda. Njira mankhwala sayenera masiku kuposa 3-4, kuyambira mankhwala ndi chomwa mankhwalawa, ndi makonzedwe yaitali kungakhale osokoneza.

Zikuonetsa ntchito "Nalbuphine"

"Nalbuphine" malangizo Buku amalimbikitsa kutenga mu syndromes amphamvu ululu umene ukhoza kulumikizidwa ndi nthawi postoperative, zikunena matenda mphuno mankhwala a matenda a mtima ndiponso a khansa.

Komanso, mankhwala chimagwiritsidwa ntchito pa nkhani ya (kukonzekera chisanadze mankhwala a wodwalayo mankhwala ochititsa dzanzi ambiri opaleshoni) prednarkoznoy premedication. Ndipotu, cholinga chachikulu cha njirayi - kuchepetsa mlingo wa nkhawa wodwalayo komanso kulimbitsa kanthu za mankhwala ochititsa dzanzi. Ndipotu, ndicho dera ntchito ya hydrochloride nalbuphine.

Ndani ayenera kupewa?

"Nalbuphine" malangizo, maganizo ndi katswiri malangizo saloledwa kuvomereza odwala hypersensitivity kwambiri kwa waukulu yogwira pophika. Inadmissible ntchito medicament zochizira odwala matenda onse a matenda a chiwindi ndi impso. Ichi ndi chifukwa chakuti zimapukusidwa "Nalbuphine" mu chiwindi. Mawonekedwe koyamba medicament ndi excreted mu mkodzo (70%) mu mawonekedwe a opangidwa kuchokera excreted mu ya ndulu lapansi.

Palibe mankhwala kutumikiridwa odwala mowa ndi kudalira mankhwala. Popanda kukufunikira mankhwala osavomerezeka ntchito ana. Popeza "nalbuphine" ndi mbali yaikulu pa malo apamwamba a ubongo, izo osavomerezeka pa mankhwala odwala maganizo osakhazikika (kwa psychosis, maganizo ndi zina zotero. N.).

Spillover zotsatira "Nalbuphine"

"Nalbuphine", ntchito yomwe ndi chifukwa chikoka chomwa mankhwalawa pa thupi la munthu, angathe kuyambitsa zotsatira zina mbali ku machitidwe osiyanasiyana ziwalo. Choncho, dongosolo mtima akhoza kuyankha ntchito medicament chitukuko tachycardia, arrhythmias, kusinthasintha magazi.

Kuyambira wamanjenje dongosolo angayambitse kupweteka kwa mutu, ndi amphamvu sedative zotsatira (ulesi), euphoria. Pali mawonetseredwe zamatsenga monga ofuntha, kuchuluka nkhawa. thirakiti m'mimba angathe kukumbukira chiwonetsero cha dyspepsia (kudzimbidwa onse).

Nthawi zina, mankhwala 'nalbuphine "(Buku malangizo apadera) zingachititse zosiyanasiyana thupi lawo siligwirizana (anaphylaxis m'gulu).

Ndipo, monga tanenera kale, "nalbuphine" - ndi chomwa mankhwalawa mankhwala, kotero zingachititse osokoneza.

Mlingo Kugwiritsa

Mlingo medicament mosamalitsa payekha kwa mlingo uliwonse wodwala anasankha malingana ndi chikhalidwe ambiri, kukula kwa zowawa, kulemera ndi zina zotero. N. Angalekanitse ntchito kwake popanda kuyang'aniridwa dokotala kungachititse kuti overdosing. Pankhaniyi, monga ulamuliro, pali zizindikiro zotsatirazi: maganizo a dongosolo chapakati mantha, ulesi, dysphoria (a loyang'ana za "euphoria" maganizo morbidly maganizo, ukugwira irritability, udali ena, chomasuka waukali, kubuka kawirikawiri maganizo). Ambiri osokoneza kungachititse wonongeka wa pakati kupuma.

Chithandizo lili mu ntchito yabwino yothetsera (kuti "Nalbuphine", monga ambiri opioids - ndi "Naloxone"), chapamimba lavage ndi mankhwala symptomatic.

mums oyembekezera ...

Pamene mimba ndi zoika "nalbuphine" malangizo amalola yekha ndi zizindikiro kwambiri. Mosamala kwambiri ndi mankhwala akuchipatala chifukwa cha kubadwa msanga ndipo nthawi kumene kukayikirana chosakhwima yoopsa. Zimenezi ndi zogwirizana ndi mfundo yakuti "nalbuphine" zokwanira mosavuta apatsira chotchinga placental ndipo angathe kuyambitsa maganizo kupuma mu neonate lapansi.

Komanso mosamala kwambiri analimbikitsa mankhwala pa yoyamwitsa, ngakhale "Nalbuphine" ndi allocated ndi mkaka mayi mu Mlingo ang'onoang'ono, opanda tanthauzo matenda (zosakwana 1% ya okwana kutumikiridwa mankhwala). Komabe, palibe kufunika kuwononga mwana popanda chifukwa lalikulu.

malangizo Special

yankho A chifukwa jakisoni chake zikuchokera 10 mg / mL wa nalbuphine hydrochloride ( "nalbuphine Farmeks"), Buku amalimbikitsa bwino ntchito matenda a ntchito kupuma, chifukwa akhoza kuchepetsa kupuma buku mphindi 25%. Kuyang'aniridwa ndi dokotala akhale odwala wochotsa "nalbuphine" ndi kufanana kwa anthu azivutika uremia ndi mawonekedwe choopsa cha kuperewera kwa zakudya m'thupi, komanso okalamba.

Kwa odwala ndi aimpso kapena kwa chiwindi mankhwala insufficiency mosamala ndi mosamalitsa payekha metered. Ziyenera kukhala zotheka mofulumira kutha kwa "Nalbuphine" kwa gulu la odwala.

Mosamala ndi akuchipatala mankhwala kwa anthu ndi kuvulala kwa Chigaza, monga pali mosavuta osauka kupuma maganizo ndondomeko. A zofunika kwambiri kuphatikiza kugwiritsa ntchito "Nalbuphine" ndi analgesics zina, chifukwa nkotheka chifooke analgesia.

Moyang'aniridwa nthawi zonse mankhwala ndi Mlingo yaing'ono mankhwala ntchito maziko a narcosis akugona mankhwala, anxiolytics, antidepressants ndi neuroleptics. Izi "oyandikana" kungakhale maganizo kwambiri ya dongosolo chapakati mantha ndi kupuma pakati maganizo ntchito.

CHENJEZO "Nalbuphine" akapatsidwa yolandirira odwala ambulatory, amene amalamulidwa ndi msewu, kapena amene ntchito zokhudzana ndi mlingo wa zochita psychomotor.

mtengo osiyanasiyana

Mtengo osiyanasiyana ndi lonse zokwanira "nalbuphine" mankhwala. Malangizo ntchito, mtengo mankhwala ndi umboni wakuti mankhwala zikufunika pakati ogula. Komanso, Analgesic wakhazikitsa yokha ngati mankhwala mogwira ogwira ntchito zaumoyo. Mankhwala phukusi "nalbuphine 20" (5 vayozi) n'zotheka kugula mu pharmacies Russia kwa ndalama mu osiyanasiyana kuchokera rubles 620 kwa 810. "Nalbuphine 10" ndalama kuchokera rubles 650 kwa 690 (paketi Mbale 10).

Mu ena pharmacies Tingaone pa malonda "Nalbuphine" mu syringe (10 mg / 1 ml), anafuna jekeseni imodzi. Mtengo wa mawonekedwe kumasulidwa ndi kuzungulira 160 rubles.

Mogwirizana ndi mankhwala ena

Monga tanena kale, "Nalbuphine" (wosuta lili mfundo zimenezi) pamodzi ndi antidepressants, anxiolytics, neuroleptics, hypnotics, wothandizila mankhwala ochititsa, mankhwala antihistaminic ndi zotsatira sedative, timapitiriza Mowa nkhawa zimakhudzanso chapakati mantha dongosolo. Kugwiritsa analgesic zikufanana ndi ena ofanana penicillin ndi phenothiazine zingachititse amveke wa kunyansidwa ndi kusanza.

"Naloxone" (adakalibe) kuchepetsa zotsatira kukhudzana ndi opioids choncho kuchepetsa kupuma maganizo ndi CNS ntchito ndondomeko zinayambitsa "Nalbuphine".

"Naltrexone" kwambiri imathandizira maonekedwe a zizindikiro za Kulipira pa maziko a mankhwala osokoneza bongo ( "mu ulemerero" Zizindikiro angaoneke pambuyo Mphindi 5 pokhapokha ka mankhwala, adzapitiriza maola 48). Symptomatology ndi wolimba kwambiri, ndi kovuta kuchotsa.

Maganizo a ogula ndi zachipatala

Odwala kulankhula za "nalbuphine" monga mankhwala mwachilungamo mogwira nthawi pambuyo zikunena mphuno Oncology. Ngakhale mavuto komanso ndi zachilendo ndipo nthawi zambiri anafotokoza mu mutu, tulo, mphwayi, m'mimba chisokonezo. Malinga ndi madokotala, "nalbuphine" (Malangizo, zikuchokera medicament ndi mfundo amene amadza tafotokozazi) ndi analgesic wabwino kwa matenda mokwanira kwambiri kugwirizana ndi ululu.

Pali gulu lina la owerenga mankhwala - mankhwala osokoneza bongo. Apa, kukambirana ndi ndemanga ndi kuchepetsedwa kwa funso ngati kanthu ndi ofanana ndi "Nalbuphine" ndi "Morphine". Zonse, umboni ndi gulu la anthu ogula Ndizachidziwikire kuti kuchilakalaka osokoneza bongo kupanga "nalbuphine" mtengo (mawerengedwe Buku odwala amenewa sakuvomereza). The mankhwala ndi wotsika mtengo (ndi zovuta mankhwala), izo zikhoza kugulidwa pa mankhwala alionse Komabe, malinga Chinsinsi. Komabe, mawu awo, "mkulu n'zolakwika, koma yopuma-mmwamba kwambiri lenileni."

Kuchokera pamwamba Ndizachidziwikire kuti "nalbuphine," Inde, ndi analgesic kwambiri. Komabe, anagulitsa yekha mankhwala - ndi zoona. Popeza payekha anasankha dokotala mlingo ndipo akafuna ntchito - ndi chitsimikizo kuti zotsatira za mankhwala m'thupi wodwala adzakhala zabwino, ndi chiopsezo mavuto - osachepera.