Nsomba tifimurium - tizilomboto, matenda, mankhwala

mabakiteriya nsomba tifimurium amadziwika mankhwala monga nsomba enterica serovar typhimurium. Ndi galamu alibe, ndodo woboola pakati mabakiteriya ndi michirayo imakhala yosiyanasiyana (wofiirira nyumba tsitsi ngati), imene chamoyo chimachititsanso.

Dzina lake mabakiteriya - chinthu chachikulu chomwe chakudya poizoni (salmonellosis) anthu. Ndi matenda ndi zambiri nkhumba, nyama nkhuku, mazira. Ziweto akhoza kupatsira izo.

Kodi nsomba anawagawira?

Choncho, ndife chidwi tifimurium nsomba - causative wothandizila cha matenda loipalo ngati nsomba. Mtundu wa nsomba enterica wapangidwa ndi 6 subspecies:

• enterica;
• salamae;
• arizonae;
• diarizonae;
• houtenae;
• indica.

Enterica subspecies enterica zikuphatikizapo nsomba izi serogroups:

• A (paratyphi A).
• B (Derby, typhimurium, agona, Heidelberg).
• C (cholerae suis, Newport, muenchen, virchowinfantis).
• D (Dublin, enteritidis, rostock, sendai, typhi).
• E (anatum).

Tifimurium nsomba (S. typhimurium)

View enterica akuti ndi tizilombo anthu ndi nyama komanso mbalame, koma chofunika kwambiri ndi ochepa iwo kwa anthu. Ndipo nthawi zambiri a salmonellosis nkhani S. typhimurium.

ta ambiri nsomba kugonjetsedwa ndi mankhwala amakono, ndi zina amafalitsidwa padziko lonse lapansi. Choncho, nosocomial salmonellosis - vuto lalikulu pa mphindi. 80% milandu nthumwi causative wa nosocomial (nosocomial) salmonellosis - ndi S. typhimurium.

zinthu pathogenicity

Ndipo ngozi chifukwa anati kwa pathogenicity matenda zifukwa zotsatirazi:

• Michirayo imakhala yosiyanasiyana amapereka kuyenda mofulumira bakiteriya a.
• Kapisozi a bakiteriya ndi kutetezedwa phagocytes. Ndipo chifukwa cha kupereŵera kwa phagocytosis osauka sepsis.

• nkhondo malowedwe Mbali kuvumbitsira kuvutanganitsidwa wopanda kwa minofu kwambiri kunama.
• Chifukwa guluu wolimba zabwino (kuphatikana), kupereka fibrils, pectins, LP-saccharide zovuta, bakiteriya ali anapitiriza mu thupi.
• Exotoxins (zinthu za ntchito zake) kupanga m'mimba ndi madzi m'thupi wotsatira, mofulumira mtima permeability.
• Endotoxin akuyima motsutsa phagocytosis zowononga. Iwo lipopolysaccharide zovuta kuti ndipamene kuledzera. Kupatsidwa zinthu za m'mwazi loitanirana mu capillaries yaing'ono zimabweretsa kutupa, pali DIC. A katulutsidwe wa Na ndi CL kumachepetsa minofu yosalala ndi kuchuluka m'mimba motility.

Kodi mabakiteriya kugonjetsedwa?

Nsomba tifimurium ndi kukana kwa zinthu zosiyanasiyana zachilengedwe:

1. miyezi itatu zasungidwa firiji zokhudza zinthu.
2. zaka zinayi kusungidwa mu ndowe wouma nyama.
3. miyezi isanu - mu madzi, theka chaka - mu mkaka ndi nyama, pa eggshells - kwa mwezi umodzi.
4. Imfa kumachitika kokha pa 100 ° C. The mankhwala nyama kukaniza mkulu ukuwonjezeka kutentha (a muyeso umodzi wa nyama ayenera owiritsa kwa maola awiri, koma ndiye abwino). Mothandizidwa ndi salting ndi kusuta sakupha nsomba.
5. tizilomboto izi chingathe kupirira kutentha kuchepa kwa -80 ° C.
6. Ndi kugonjetsedwa UV kuwala.
7. tizilombo toyambitsa matenda ali wofunikila kupirira Mphindi 20 kupha mabakiteriya.

Kubuka salmonellosis zochitika anati m'chilimwe, nthawi zambiri matenda ana chifukwa cha zolakwa za kachitidwe kawo m'thupi.

Kudwala kudzera mwa alimentary kulankhula ndi kukhudzana-banja. Mwa njira, n'kofunika kugwiritsa ntchito mazira kulabadira mtundu wa mapuloteni ndi yolk. Pamene turbidity, kukha mwazi fungo yoola, dzira n'kumene kachilombo. Izo ziyenera kuchotsedwa, mbale kutsanulira chlorine manja iwo kusamalira. Sopo milandu sikuthandiza.

Zima kung'anima, imfa mkulu ndi kufala kukhudzana-banja limagwirira wa mankhwala opha tizilombo zimachitika zifukwa ndi chifukwa chakuti chitetezo chakudya centralized.

nthawi makulitsidwe

Nthawi makulitsidwe kumatenga maola sikisi eyiti tsiku, koma nthawi zambiri zizindikiro adzawonekera mu tsiku loyamba kapena awiri mutadya mankhwala zakhudzana.

Ndi kuphwanya kagayidwe madzi amchere chifukwa m'mimba, chopondapo amakhala madzi, frothy, onunkha, amadyera, amatikumbutsa "chithaphwi matope" ndi pafupipafupi nthawi teni ndi tsiku, mlungu umodzi kapena kuposerapo.

Matendawa akuyamba bwinobwino, amakhala ndi kufooka, ulesi, ululu wofatsa m'mimba (epigastric ndi umbilicus). Pamimba ndi zopweteka pa palpation, lomveka kuwayula ndi kutupa chimaonekadi.

Nsomba tifimurium - Laboratory Diagnostics

Pa matenda anakhudzidwa ndi magawo zotsatirazi:

• kuchuluka erythrocyte mlingo sedimentation;
• leukocytes ndi anasintha lamanzere;

Tizilomboto wapezeka kwa madzi kwachilengedwenso (ndowe, magazi, mkodzo, limba anakhudzidwa) ndi mankhwala Muzisamala bacteriological njira. Zotsatira zake zomalizira, monga ulamuliro, lokonzedwa ndi tsiku lachisanu.

Pa matenda ndi nsomba tifimurium, zizindikiro zotsatirazi:

• malungo;
• kuzizira;
• m'mimba chaukali;
• kusanza.

chithandizo

Matenda akhoza chakupha kutangoyamba, okalamba ndi odwala ndi chitetezo chokwanira wotsikirapo. Ndipo yoopsa nsomba tifimurium.

Chithandizo ndi ntchito maantibayotiki ndi zakumwa zobwezeretsa. Komanso mankhwala MANKHWALA OLETSA VUTOLI, kukonzekera enzyme, sorbents, antidiarrheals. "Table №4» zikusonyeza zakudya.

Therapy ayenera kuonedwa moyang'aniridwa okhwima achipatala, ndi miyeso resuscitative ntchito Zikavuta. Wa sorbents kwa detoxification cha thupi ndi bwino kugwiritsa ntchito mankhwala zotsatirazi:

• "Enterosgel";
• "Liferana";
• adamulowetsa mpweya;
• "Smecta";
• "Enterodeza".

Ndi kawirikawiri kulimbikira kusanza ndi kuvomerezedwa kuti itanani ambulansi pofuna kupewa madzi m'thupi. Wodwala kawirikawiri Kwalamulidwa "Regidron". Kuchuluka kutentha amachepetsa antipyretics.

Yogwira ndi nsomba nsomba enterica mankhwala

Antibacterial wothandizila yogwira ndi nsomba nsomba enterica, "kuchita furazolidone" "Ciprofloxacin", "Rifaximin", "nifuroxazide". Koma iwo angakhoze kokha mankhwala dokotala, kutola mlingo munthu ndi kutenga nkhani ya mmene wodwalayo, ndi kachilombo nsomba tifimurium.