Tochepa ndi kukwezeka - ndani ndi chochita.

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Tochepa - ndi timadzi steroid, cha gulu la glucocorticoids, omwe amatuluka mu kotekisi adrenal. Tochepa amapangidwa zambiri kukachitika kuti thupi la munthu wadwala nkhawa kwambiri, ndipo ngati mlingo ambiri glucocorticoids m'magazi utachepa.

thupi tochepa amagwira ntchito zosiyanasiyana, makamaka timadzi ichi kumapangitsa gluconeogenesis, potero kukula kuchuluka kwa shuga kufalitsidwa magazi. Komanso, timadzi imeneyi amagwira ntchito yofunika kwambiri mu kupondereza chitetezo cha m'thupi, komanso mu kagayidwe chakudya, mafuta ndi mapuloteni mu thupi la munthu.

Cortisone kawirikawiri kuchuluka woyembekezera, ndi zachilendo ndipo chifukwa chakuti timadzi izi kulimbikitsa ulimi wa surfactant mu mwana wosabadwayo pa gestation masabata 30. Mwa njira, nthawi zambiri ndi kupanga mtundu wa timadzi ntchito monga medicament zochizira matenda osiyanasiyana enaake ophwanya kapena kutupa, chifuwa, ndi matenda Addison a.

Mwachibadwa, kwa mlingo munthu wa timadzi izi ndiyo pang'ono kukwezeka m'mawa ndi madzulo mlingo wake m'magazi ndichepe. Ngakhale nkhawa ndipo sangatengedwe kukhala chifukwa yekha kutsegula kwa kaphatikizidwe wa timadzi, koma ndi kupanikizika Nthawi zambiri amayambitsa kuwonjezeka mu ndende zake, kukhetsa mwazi kumene Timapindula. Makamaka chifukwa chakuti panthaŵi zovuta kukwezeka cortisone anthu pali mkangano zina mphamvu, amene makamaka zofunika mwadzidzidzi, pamene aliyense udindo wachiwiri. Komanso, kuwonjezereka pang'ono tochepa kumapangitsa chitetezo cha m'thupi, dulls ululu, bwino ubongo, kuwalola kusunga malangizo zambiri, komanso amathandiza kuti tikhalebe homeostasis yachibadwa thupi lonse.

Iwo ayenera kumvetsa kuti kusintha zonse zingakhale zothandiza ngati kuchuluka tochepa limapezeka nthawi, i.e. ngati chamoyo kuchokera nkhawa ndi milingo kupumula wa timadzi wa yafupika. Ngati chakudya cha lamulo la mpumulo thupi salandira, ndiye tochepa pang'onopang'ono kupereka kubwerera kuti ndi zotsatira pathological. Makamaka, mu malo oyamba, izo amadwala ubongo, ndicho ake luso chidziwitso. Komanso, mu chochitika kuchuluka tochepa kawirikawiri kwambiri yafupika minofu misa ndi mafupa, utachepa ntchito pammero ndipo magazi kukacha.

Ndithu chabe kudziteteza ku zotsatira zoipa za "maganizo timadzi," tochepa. Zochepetsera wokhutira m'magazi, angathe kuphunzitsa msonkhano uliwonse pa zosangalatsa - kufunika kuphunzira njira kudziletsa zosangalatsa, kuchita masewera olimbitsa thupi ndi ambiri amasangalala moyo.

Koma palinso zinthu zimene nthenda tochepa kaphatikizidwe ndi zosagwirizana ndi boma maganizo a wodwala. Makamaka kwa mitundu ina ya pathologies. Kukachitika kuti kuchuluka tochepa, ndi timadzi kuti amachepetsa chiwerengero cha kolajeni pakhungu, ndipo kumachepetsa katulutsidwe wa histamine. Komanso, tochepa kwambiri amakhudza pa ziwalo zoberekera za thupi ndi yokulirapo ndi wolingalira ukuwonjezeka wokhutira m'magazi akhoza kuyambitsa padera odwala pakati. Yobereketsa kubwerera mwakale pambuyo mlingo wa timadzi mu amachepetsa magazi.

Tochepa akhoza ziwonjezeke ndi magulu a matenda otsatirawa:

• syndrome Cushing a

• adrenal England chotupa

• ectopic ACTH syndrome kaphatikizidwe

  Tochepa akhoza adatchithisira pansi magulu awa a matenda:

• apituitarism

• matenda Addison a

  Pa kafukufuku, zimene zingakuthandizeni kudziwa kuchuluka kwa tochepa m'magazi, m'pofunika kuganizira mfundo yakuti wokhutira mwa magazi imene ingakhudze phwando mankhwala osiyanasiyana. Makamaka, tochepa kwambiri chifukwa pambuyo mankhwala olera kapena mankhwala ena okhala estrogens zosiyanasiyana.