Corinfar. Malangizo ntchito

"Corinfar" ndi antagonist wa calcium, i.e. izo kumabwezera mmbuyo malowedwe a Ca2 + m'chipinda minofu (cardiomyocyte), mtima ndi mitsempha ya magazi kuchokera danga intercellular. Choncho, kuchepetsa mu ndende ya ayoni calcium. Chifukwa cha yowonjezera zotumphukira, mitsempha inatsekeratu ndi arterioles (mtsempha wamagazi zofewa). Miyala kukhala kanthu yaitali, anatchula ntchito vasodilating.

Medicine "Corinfar" amapangidwa mu mawonekedwe a mapiritsi wozungulira biconvex TACHIMATA ndi ❖ kuyanika chikasu filimu. piritsi limodzi lili yogwira mankhwala - nifedipine (apanga chongopeka ku dihydropyridine a) - 10 mg. Monga zinthu wothandiza, piritsi kudzazidwa ntchito lactose monohydrate, povidone K25, wowuma mbatata, microcrystalline mapadi, magnesium stearate. "Corinfar" amagulitsidwa katoni matuza atatu (mapiritsi 10) kapena mabotolo mdima galasi miyala 50 100.

Mu matenda monga angina, matenda oopsa (kulimbikira BP), odwala Kwalamulidwa "Corinfar". Malangizo ntchito wasenza mu Russian. Zonse zomwe lipindulitsa osati ogwira ntchito zaumoyo ndi madokotala komanso odwala, monga zikuthandizani kumvetsa atasankhidwa dokotala, komanso kusintha mu thupi, yomwe ndi chotsatira chake cha zotsatira za mankhwala.

Amadziwika kuti zotsatira achire adzakhala yochulukirapo (popanda kuchepetsa mayamwidwe wa chinthu yogwira - nifedipine), ngati akamadya kuti "Corinfar". Malangizo ntchito akulimbikitsidwa kutero (osati madzi) pambuyo chakudya ndi kumamwa kowirikiza madzi. Kutalika ndi mlingo (ie, chithandizo) amasankhidwa payekha ndi zotchulidwa dokotala. Onetsetsani kuganizira kudziwa corinfar ndi kukula kwa matendawa. Kwa odwala okalamba komanso amene akudwala aakulu concomitant matenda cerebrovascular, kuchepetsa mlingo.

Kuyambira ndi 10 mg wa nifedipine (kapena piritsi 1 kawiri kapena katatu pa tsiku) kutenga "Corinfar". Malangizo ntchito amalola kuwonjezeka pang'onopang'ono mlingo kuti mapiritsi 2 kapena 20 mg ndi kamodzi kapena kawiri pa tsiku. Zolemba malire tsiku mlingo sayenera kuposa 4, kapena 40 mg. Mu matenda oopsa zofunika (matenda oopsa), analimbikitsa pafupifupi tsiku mlingo ayenera kukhala piritsi 1 kapena 10 mg (ankaona pa nifedipine) kawiri atatu patsiku. Pofuna kukwaniritsa kufunika kwenikweni matenda, mlingo zotchulidwa dokotala akhoza ziwonjezeke kwa 40 mg (monga nifedipine) patsiku, kumwedwa kwa nthawi 2. Pakati pa njira ziwiri corinfar pa cholinga thuu kapena atatu khola, nthawi imeneyi ayenera kukhala maola osachepera anayi.

Mu matenda ena, osavomerezeka "Corinfar". Malangizo ntchito contra limasonyeza wolumikizira ake hypotension, cardiogenic mantha, kugwa, kulephera aakulu mtima, odwala ndi aakulu kung'ambika stenosis, wosakhazikika angina, pachimake m'mnyewa wamtima infarction (pankhondo yoyamba masabata anayi), ntchito limodzi ndi rifampicin. Pali komanso contraindications mkaka wa m'mawere mu trimester hypersensitivity kuti nifedipine kapena zosakaniza wothandiza.

kusamalidwa chofunika hypertrophic obstructive cardiomyopathy, mitral vavu stenosis, odwala nkusani syndrome, tachycardia kwambiri kapena bradycardia, hypovolemia, matenda oopsa oopsa, m'mnyewa wamtima infarction ndi kulephera kumanzere yamitsempha yamagazi, aakulu cerebrovascular matenda. Komanso aimpso ndi chiwindi kulephera, m'mimba kutsekeka thirakiti, aimpso dialysis, panthaŵi II ndi III trimesters mimba asanafike zaka zaka 18, tikadwala beta-blockers, digoxin.

lokonzekera ali ndi kutchulidwa antihypertensive ndi antianginal zotsatira zotsatira chosunga chifukwa kanthu kuchedwa kwa yogwira mankhwala nazyvetsya "Corinfar achigonjetse". Buku kakunena kwa zachipatala ndi odwala. The yogwira pophika mankhwala mosavuta odzipereka kwa mundawo m'mimba. Zotsatira achire ndi zosaposa 15 Mphindi pambuyo makonzedwe mankhwala. Kagayidwe zigawo "corinfar" amapezeka m'chiwindi chifukwa hydrolyzation ndi makutidwe ndi okosijeni. Kagayidwe wa nifedipine umatulutsa mankhwala kulalikira. Kusonyeza "Corinfar" makamaka ndi impso, komanso ndowe.