"Flutamide": malangizo ntchito, ikulongosola za mankhwala, analogues ndi zotsatira zake zoyipa

"Flutamide" Ndi mmodzi wa mankhwala odana androgen ndi ntchito kuthetsa zizindikiro androgenization. Amatha kuchepetsa kagayidwe mahomoni androgenic ndi bwino chimafikira zotsatira ziwalo thandizo la mankhwala. Cholinga cha mankhwala - pa yimitsira wa timadzi mwamuna, pakuti mpumulo wa matenda oyamba ndi owonjezera izo.

katundu pharmacological

Kukonzekera "Flutamide-250" ntchito pa matenda a amuna ndi akazi ndi zizindikiro za kuchuluka testosterone akuvutika mavuto ndi kuwonekera kwa timadzi izi. mankhwala Non-steroidal ziletsa biosynthesis wa androgens ndi katulutsidwe wa zopangitsa yafupika kupanga gonadotropin ndi kuchepetsa ambiri androgens mamolekyulu yogwira. Mankhwala imayendetsa njira kagayidwe kachakudya, timapitiriza ntchito kagayidwe kachakudya mu kuchotsa mahomoni owonjezera excreted.

Zimatanthauza gulu la mankhwala si steroidal ndi antagonizes 5-a-reductase. Chikuonetseratu "flutamide" alibe mphamvu pa ulimi wa gonadotropin mu pituitary England ndipo kumachepetsa ntchito gonadotrophic.

Zikuonetsa yopemphera

Mphamvu ya mankhwala kumabweretsa zotsatira zovuta pa ndondomeko ya kuchepetsa mlingo wa timadzi yogwira. Chifukwa chimene ntchito "flutamide"? Malangizo ntchito limasonyeza kuchepetsa, ndipo kenako androgenization ndondomeko braking.

Chifukwa kuwonjezera kupanga androgen kumatheka ntchito za enzyme 5-α-, nawo kubalana wa khungu ndi lilime lake amalimbikitsa kudziwa mahomoni izi. Motero amayamba kukula kwa idiopathic hirsutism thandizo la mankhwala.

Mpaka posachedwapa yoikidwiratu zochizira hyperplasia Prostatic anthu, koma osati kale zinawululidwa zotsatira zake zabwino kuchipatalako bwino matenda ena likukhudza amayi. Hirsutism, alopecia "flutamide" kwa akazi pa phwando tsiku ndi tsiku kwa miyezi itatu ndi okwanira bwino kuchepetsa magazi kuchuluka Kuchuluka kwa timadzi amphongo ndi matenda amenewa akusiya mwamphamvu awo.

Matenda chomwe chili kutenga mankhwala

• khansa Prostate ndi kufala kwa metastases anthu.
• Hirsutism ndi alopecia mu akazi.
• Pamene opaleshoni castration a anthu.
• Pamene matenda m'thupi ndi zizindikiro za ziphuphu zakumaso.
• Mu padera kapena kulephera kutenga pakati.

The zizindikiro zazikulu ndi zizindikiro zokayikitsa cha overabundance wa testosterone mu thupi. Mu akazi, owonjezera thupi tsitsi ndi chitsanzo wamwamuna dazi, matenda kusamba ndi zina zotero. D. Palinso mahomoni kagayidwe kachakudya ndi zizindikiro zobisika monga anovulation, hypoplasia la chiberekero ndi zopangitsa mammary.

Kuti matenda dokotala zolondola chimaika kuunikidwa zina, zomwe zikusonyeza kuti tinafotokoza mwatsatanetsatane MAGAZI pa boma la mlingo wa mahomoni osiyanasiyana m'thupi.

Independent ntchito mankhwala, popanda umboni wa dokotala nawo, kungawononge mpaka kalekale thanzi. Mankhwala mankhwala ayenera mosamalitsa dokotala!

phwando Features

Kukonzekera "flutamide" malangizo Buku limasonyeza kukwaniritsa ndende pazipita m'magazi maola 2-3 pambuyo chikuonetseratu, kusonyeza absorbability mofulumira mankhwala intestine. Hafu ya moyo pafupifupi 5-6 maola mu mkodzo, ndipo Patatha maola 8-9, otsala ndi linanena bungwe. Quality kuswana zimadalira m'badwo wodwalayo ndi thanzi akukhudzidwira.

Matenda ndi zizindikiro androgenization akazi amafunika chithandizo payekha. Kuona mmene, mwamphamvu, malo m'madera vuto ndi zinthu zina zimakhudza kupereka mankhwala, kawirikawiri "flutamide" amagwira ntchito phwando zovuta. Malangizo ntchito limasonyeza triply phwando masana kapisozi mmodzi, kusunga nthaŵi. Mlingo tsiku la 750 mg, nthawi osachepera mankhwala masabata asanu.

zizindikiro za mankhwala chifukwa kuchuluka zili androgens ayenera pamodzi ndi ena mankhwala ena katundu odana ndi androgenic. Nthawi zambiri osakaniza yoikika "Dexamethasone", "Prednisolone" ndipo atumiki ena corticosteroid. Ikani ndi otonthoza mankhwala kuthandiza nkhani maganizo odwala ndi simtomov zoonekera chifukwa cha chipolowe mahomoni.

Ngakhale sitili zizindikiro kale nkhawa kuletsa mankhwala yekha osavomerezeka chifukwa zosowa kufunsa munthu wina m'thupi yemwenso, kutsatira chitukuko cha matenda. Ziyenera kukhala okhwima zoletsedwa ndi malamulo onse pa mankhwala. Ngati pa zifukwa zina kuikidwa anali ataphonya mankhwala, muyenera kusamala ndi ziwiri, ndi kupitirira phwando yachibadwa. Akulumphalumpha mankhwala si monga oipa monga limodzi kulandira mlingo awiri.

Fomu kumasulidwa

Yopangidwa mu mawonekedwe a makapisozi kapena miyala filimu TACHIMATA. Oyenera phwando m'kamwa. Kugwiritsa yogwira mankhwala - flutamide 250 mg.

Pharmacies "flutamide" chogulitsidwa yekha ndi mankhwala.

Kusunga mu ozizira, youma patali ana.

Kupanga - Orion Corporation, kampani mankhwala (Finland).

Pa "flutamide" mtengo kuchokera 1798 kuti rubles 1968 pa paketi (mapiritsi 84).

contraindications

Monga taonera zimene zinachitikira pa matenda a akazi motalika kokwanira, kwenikweni izo nkhawa kumachitika mu chidziwitso cha mavuto ndi mavuto pa chiwindi. Choncho, ngakhale efficacy mkulu, mankhwala ayenera kugwiritsidwa ntchito mosamala, kutsatira malangizo a madotolo.

• Ndikoletsedwa phwando "flutamide" odwala matenda a chithokomiro England, chiwindi ndi impso.
• Hypersensitivity mankhwala "Flutamide."
• Contraindications matenda a impso, chiwindi ndi kapamba.
• CHENJEZO kutenga propensity kupanga magazi kuundana ndi matenda a dongosolo mtima.

Mogwirizana ndi mankhwala ena

Musanagwiritse ntchito mankhwala osavomerezeka kuuza dokotala mankhwala atengedwa zonse. dokotala ayenera kuganizira mavitamini amadandaula, zowonjezera chakudya, mpaka phwando adamulowetsa mpweya.

• "Flutamide" pamene ntchito mankhwala ena amatha potentiate antiogulyantov choncho amafuna moyenera mlingo mawerengedwe, kutenga mogwirizana nkhani.
• Kusuta ndi kumwa mowa komanso kusintha zochita za mankhwala m'thupi. Pa phwando adzakhala zomveka kusiya zizolowezi zoipa.
• About matenda alipo magazi dokotala ayenera kuuzidwa.
• Ngati mukufuna mimba, onetsetsani kuti dokotala anu phwando zina.
• Nenani, thupi lawo siligwirizana ndi mankhwala, ndipo ngati iwo akudziwa izo.

ambiri osokoneza

Ngati ndi mwayi uliwonse watengedwa mapiritsi chachikulu mlingo "flutamide," m'pofunika chapamimba lavage ndi chithandizo kuchipatala kapena "ambulansi". Zotsatira za mankhwala osokoneza bongo zingachititse okhazikika kwambiri kuwongola kupondereza timadzi kapena gonadotrophin kwathunthu kuletsa kupanga amadwala matenda wina. Choncho ndikofunikira zoletsedwa ndi malamulo, kutenga "flutamide" malangizo ntchito amatanthauza potsatira kwambiri mlingo ndi dokotala.

mbali zotsatira

Pambuyo yaitali ntchito munthu angathe kudziwa zizindikiro za gynecomastia, kupweteka pachifuwa, madzimadzi posungira.

Ngati zochitika zotsatirazi, zomwe zingakhale zinthu yosavuta thupi, mankhwala ayenera kukambirana dokotala anu, makamaka ngati izi zisanachitike sanali.

Zizindikiro mavuto

• Kudzimbidwa.
• Violation kudya.
• Ndichepe mu libido.
• M'mawere kukulitsa mu amuna.
• Maganizo limati.
• Kulakwila kugona ndi maso.
• Kutupa.
• Kusintha mkodzo mtundu.
• Kutopa.

Kulanga Anachita Atamva - infrequent, koma zizindikiro bwino kudziwitsa adokotala akhoza kusintha chinachake mu njira mankhwala kapena kusiya mankhwala.

analogs

Antiandrogens - gulu la mankhwala ndi chuma cha kupondereza m'badwo kwambiri a progesterone kuchititsa chisokonezo amaonekera thanzi wodwalayo. Ndi zomwezo "flutamide" otsatirawa mankhwala si steroidal akhoza zimachitika pa katundu ndi zikuchokera:

• "Cyproterone" - yokonza ambiri ndi gulu la progestogens ntchito antigonadotropnym.
• "Spironolactone" ( "Veroshpiron"). The chachiwiri wotchuka kwambiri mankhwala, replaceable "flutamide" mfundo za chikoka ofanana ndithu, mwinanso osiyana.

Isanayambe phwando gulu iliyonse ya mankhwala kuonetsetsa kuti gwero la matenda si ofanana mimba chotupa. Pamafunika kukonzekera bwino kuti njira mankhwalawa hyperandrogenism, kutenga mu contraindications chifukwa ndi makhalidwe munthu aliyense wodwala. Nkofunika pa phwando pa dokotala anafotokoza mwatsatanetsatane zizindikiro ndi kuwonekera kwa matenda, lotchedwa matenda aakulu alipo, makamaka ngati iwo ali oyanjana ndi ntchito chiwindi, njira yokha dokotala akhoza kusankha mankhwala ndiwofatsa molumikizana ndi "flutamide."

Reviews

Mwachidule nkhani za mayankho za mphamvu ya mankhwala "Flutamide." Reviews akhoza akambirana anthu amene achitiridwa. Mu akazi akudwala zizindikiro za hirsutism, ndi normalization kukula tsitsi. The zopangitsa sebaceous pakhungu, kuchititsa ziphuphu zakumaso, komanso anapezanso ntchito zake bwinobwino.

Koma nthawi zina kuti si zothandiza kwambiri "flutamide" ndemanga sanali atsimikizire dalitso lapadera kulandira, ndi zambiri chifukwa ndi matenda olakwika kapena zolakwika ntchito. Odwala ena musati kubweretsa njira yaitali mankhwala mpaka mapeto a mtengo wa mankhwala, mu nkhani iyi, inu mukhoza kukaonana ndi dokotala wanu ndipo adasonkhananso kwa Anzawo mtengo, kotero kuti asiye mankhwala. Pa "flutamide" mtengo si mkulu ndipo muyenera kuchita zimenezo, mankhwala yaitali ndithu ndipo zina kuba ndalama.

Kusamala

Pamene mankhwala zovuta masiku atatu patsogolo ntchito GnRH agonist ayenera kumwedwa "flutamide" kuchepetsa mosavuta mavuto. Pamene chiwindi kulephera mankhwala akusonyeza kokha ngati njira yokhayo kuti zochimwazo kumathetsa mavuto athu. Izo ziyenera kuchitikira zasayansi kuphunzira ntchito ya chiwindi. Panali ena kuwonjezeka chiwindi pamene kulandira "flutamide," koma pambuyo Kulipira amakhala chigamulocho yachibadwa. Zizindikiro osafunika bwino kuchotsa mankhwala.

Zoyenera zasayansi mayesero kuwunika chiwindi mayesero ntchito ayenera kuchitidwa kwa wodwala aliyense kamodzi pa mwezi pa miyezi 4, ndiyeno nthawi kapena pa chitukuko cha zizindikiro woyamba wa matenda kwa chiwindi ntchito (kuyabwa, mdima mkodzo, imfa azilandira chakudya, matenda a chikasu ndiyo, mavuto mu lamanja nusu chapamwamba). Kwa nthawi yaitali anthu amachitira, pakalibe mankhwala kapena opaleshoni castration ayenera nthawi zonse zili umuna kuteteza chonde.

Pa nkhani ya galimoto galimoto ndi njira kasamalidwe maphunziro akhala akufufuza. Koma ngati muli zizindikiro zilizonse monga chizungulire kapena mutu, si bwino kutenga mavuto osati kukhala kumbuyo gudumu.