"Genferon Kuwala" (kutsitsi): malangizo ntchito kwenikweni

Pamene pali kusapeza aliyense, ine ndikufuna kuti amuchotsepo Iye, kotero pofunafuna mankhwala amene angathe mu nthawi yaifupi zotheka kuthandiza imeneyi amagwira ntchito yofunika kusankha chithandizo. Kumatanthauza kuti kuyambitsa yomweyo khama zotsatira zake pambuyo ka matenda pachimake kupuma ndi fuluwenza, mankhwala ndi "Genferon Kuwala" (kutsitsi), ogwira mankhwala ndi kupewa chimfine tizilombo. Ichi ndi chifukwa kusankha molondola njira za makonzedwe, amene mankhwala aperekedwa mwachindunji ku malo oyamba tizilomboto mu thupi (chipata cha matenda), komanso zikuchokera mankhwala, womwenso interferon ndi taurine.

achire

mankhwala ili gulu la immunomodulators. Amakhala zophatikizananso interferon anthu alpha-2b, analandira ntchito kupsyinjika mabakiteriya Escherichia coli, limene, ndi kukonza majini a interferon anthu linayikidwa jini ali chuma kuwonjezera chitetezo cha m'thupi, ndi taurine pawiri akapha ndi kanthu antimicrobial.

Mankhwala akusonyeza chinthu zovuta:

• immunomodulatory ndi zolimbikitsa, ndiko kugwirizana ndi ntchito kulimbikitsa chitetezo cha m'thupi, akuwonetseredwa chifukwa alpha-2b-interferon;
• mavairasi oyambitsa, yodziwika kupondereza ntchito ndi luso kubereka tizilomboto pa mfundo yolowera thupi;
• antiproliferative, wopangidwa mu yimitsira maselo bakiteriya kukula ndi khansara;
• nkhoswe antibacterial;
• odana ndi yotupa.

Ndi immunostimulatory ndi ntchito mavairasi oyambitsa wa mankhwala "Genferon Kuwala" (kutsitsi), zomwe amakambirana ntchito dziwani Mwachangu ake okwezeka ndi SARS, pambuyo oyamba mu ndime m'mphuno yomweyo akuyamba kuchita ndi inhibiting chitukuko cha matenda pa magawo oyambirira.

limagwirira kanthu

Kupeza pa mucosa wa m'mphuno, mankhwala ali ndi Amowabu kanthu wamba cholinga cha matenda ndi amadza chonse pa thupi lonse.

Limagwirira ambiri amayamba ndi katundu wa yogwira zosakaniza ali kukonzekera "Genferon Kuwala" (Utsi):

• mavairasi oyambitsa amadza chifukwa kutsegula kwa michere okhudza maselo ambiri kuti kubisa chulutsa mavairasi ;
• ntchito immunomodulating chifukwa kuchuluka reactivity wa asilikali a chitetezo cha chamoyo, amene amagwirizana ndi kukondoweza maselo CD8 + T-wakupha, maselo NK, kuchuluka zosiyanasiyana za B-lymphocytes ndi kupanga chitetezo ndi chitetezo chokwanira ma zinthu zina;
• kumachitika zolimbikitsa monocyte-macrophage phagocytosis KA MASANKO, komanso kukula mawu a maselo zofunika zovuta udindo histocompatibility yoyamba (amene kumawonjezera Mwina wa kuzindikira za maselo ndi nthumwi za chitetezo cha m'thupi la thupi;
• kutsegula kwa maselo oyera amenewa amapezeka pansi zochita za interferon, chomwe ndi mbali ya mankhwala amalola yotithandiza zigawo kuteteza ng'ombe mucosa, kulola kulowerera kwawo mwachindunji yimitsira a zotupa;
• Komanso pansi pa wapaulendoyo wa interferon anthu abwezeretsedwa kupanga chinthu choterocho chitetezo monga secretory immunoglobulin A;
• kungotchula yozungulira antibacterial zotsatira za utithandize ayankhe m'thupi kuti kumachitika chifukwa oyamba interferon;
• normalization njira kagayidwe kachakudya ndi kuonjezera mphamvu regenerative minofu amapezeka pansi zochita za taurine, ndi kukhala Kakhungu ofunika ntchito immunomodulatory;
• taurine, monga antioxidant ndi, kumathandiza kudzikundikira ufulu mpweya zimakhala, amene kuchepetsa kufala njira pathological mwa iwo;
• interferon, kusintha njira kagayidwe kachakudya maselo zing'onozing'ono wothandizila opatsirana monga tizilombo kapena chlamydia, ndondomeko chingaimitse kafalitsidwe awo ndi kugawa.

Fomu kumasulidwa

Mankhwala "Genferon" amapangidwa mu mawonekedwe a suppositories ndi opopera. Yotsirizira ndi kuwala mandala madzi akachita opanikizika mu mdima galasi vial mathero dispenser anapereka ndi kapu zozitetezera. Kenaka kwa Mlingo 100 munali 50 000 IU wa interferon alfa-2b zophatikizananso anthu ndi 0,001 ga taurine uliwonse. Wa zigawo zina zikhoza olekanitsidwa disodium edetate digidratat, glycerol, dextran, polysorbate, sodium ndi mankhwala enaake potassium peppermint mafuta amene ayenera kuwaganizira ngati pali hypersensitive wina wa zinthu zimenezi. Suppositories anafuna makonzedwe thumbo kapena ukazi, amapangidwa mu Mlingo awiri (120 000 kapena 250 000 IU), zomwe zimawachititsa oyenera akulu ndi ana, malinga ndi kufunika anazindikira.

zikuonetsa

Mankhwala "Genferon Kuwala" (utsi) wasonyeza mkulu efficacy m'mayesero matenda zochizira ndi kupewa fuluwenza ndi matenda ena pachimake kupuma mu akulu ndi ana oposa zaka 14, amene amalola kuti amalangiza cholinga chimenecho.

kutsitsi Izi zikhoza kokha kuwonedwa ngati mankhwala a chimfine, monga umagwira ntchito zovuta pa boma lake lonse ndi inhibiting chulutsa mavairasi mu malo a Polojekiti (leni mucosa a dongosolo kupuma), kupatulapo chitukuko wotsagana zomera bakiteriya ndi zolimbikitsa thupi chitetezo munthu.

Kuchita zimenezo conjoint amalola matenda ambiri amalangiza mankhwala "Genferon Kuwala" (kutsitsi). Malangizo limanena za dzuwa ake okwezeka:

• monga njira kuchiza matendawo tizilombo, makamaka kupuma thirakiti kuteteza asayembekezere, makamaka pa miliri;
• ngati mankhwala othandiza kuti pachimake ndi aakulu sinusitis, matenda, pharyngitis, laryngitis, tracheitis, zilonda zapakhosi ndi matenda ena;
• kubwezeretsa chitetezo chokwanira ina ku nthawi pambuyo mankhwala a fuluwenza ndi matenda ena pachimake kupuma tizilombo;
• pokonzekera opaleshoni voti mu kapepala chapamwamba kupuma ndi pambuyo pawo.

contraindications

Mankhwala "Genferon Kuwala" (kutsitsi), ndemanga za mankhwala amene amasonyeza yimitsira ogwira chimfine pa magawo oyambirira, angagwiritsidwe ntchito si aliyense. Musati am'sankhe,

• anthu ali ndi tilinazo kuchuluka kwa interferon alpha-2b, taurine kapena zigawo zina amapanga mankhwala;
• ana osaposera zaka 14, kuyambira kutsitsi lilipo yekha ndi Mlingo wa akulu;
• odwala ndi khunyu kapena matenda aakulu mtima.

Odwala amene ali ndi chizolowezi maonekedwe a magazi m'mphuno ayenera kugwiritsa ntchito mankhwala mosamala.

Kukonzekera "Genferon Kuwala" (kutsitsi) malangizo ntchito, mlingo

Pamene mawonetseredwe a zizindikiro choyamba cha matenda ayenera kuyamba chithandizo ndi mankhwala. Kugwiritsa ntchito bwino malamulo ochepa ayenera kutsata:

• pambuyo pochotsa kapu zoteteza ndi mbamuikha kangapo dispenser mpaka kwapang'onopang'ono mankhwala (pamene ankakonda kutenga mbale izi);
• Utsi atagwira vertically yochepa atolankhani (1 mlingo wa yogwira pophika) chikuyendetsedwera mankhwala aliyense mphuno iwonso;
• pofuna kupewa kufalikira kwa matenda, aliyense vial ayenera kugwiritsidwa ntchito payekha.

Amalangiza ziwembu ntchito ziwiri:

• Malinga woyamba, anadzetsa lililonse mphuno wa mankhwala umodzi mlingo katatu pa tsiku kwa masiku asanu;
• Chachiwiri njira - kupemereredwa kutumikiridwa pa mlingo uliwonse mphuno kwa maola 3-4 choyamba, kuyambitsa mankhwala aliyense mphindi 20 namtsata ndi makonzedwe mankhwala kwa masiku 3-4 maulendo 5 tsiku.

The pazipita kololeka tsiku kuchuluka kwa mankhwala ndi Mlingo 10.

Mankhwala "Genferon Kuwala" (kutsitsi): Malangizo ntchito ana

Yogwira immunomodulator amapangidwa m'njira ziwiri mlingo - monga suppositories thumbo kukhala okhutira yosiyanasiyana ya mankhwala yogwira mu mawonekedwe a kutsitsi ndi. Izo zimatengera zili zapansi mankhwala poika mankhwala kwa ana. Makandulo opangidwa ku Mlingo awiri: nkhani 250,000 IU wa interferon alfa-2b, amene analamula ana ndi akulu zaka zoposa 7 zaka, ndi mlingo wa 125.000 INE, ntchito zomwe zili zotheka ngakhale mankhwalawa neonates. Malangizo loletsa kugwiritsa ntchito "Genferon Kuwala" mankhwala (kutsitsi) ana. Reviews onani ntchito wabwino wa suppositories mankhwala zovuta za SARS, zofuna ambiri anasonyeza mu maonekedwe a kutsitsi ndi ana ngati yabwino ntchito. Pa nthawi yomweyo amaloledwa kuti asankhe yekha mwanayo ukufika zaka 14.

Gwiritsani mimba

A chikhalidwe chapadera cha thupi wamkazi, kugwirizana ndi mwana wobala mwana, amafuna njira mosamala kusankha mankhwala, monga ambiri a iwo kwathunthu contraindicated mayi woyembekezera, kapena kugwiritsidwa ntchito mosamala, ngati kuyembekezera phindu n'kosangalatsa chiopsezo kuthekera kwa mwana wosabadwayo. Ikani mankhwala "Genferon Kuwala" (kutsitsi) pa mimba amaloledwa pa siteji iliyonse, kuyambira maphunziro analibe mavuto mankhwala pa mwana wosabadwayo. M'malo mwake, pa chiopsezo matenda (mwachitsanzo, mu nyengo ya kuchuluka odwala kapena kukhudzana ndi kale kudwala) mayi woyembekezerayo akulimbikitsidwa kugwiritsa ntchito kutsitsi ili ngati muyeso prophylactic. Ichi ndi chifukwa mtembo wa pakati kuti atengeke chimfine chifukwa chiwerengerocho chifukwa cha kukana ake zinthu zoipa.

Ntchito kutsitsi pa yoyamwitsa

Chiletso cha ntchito zamitundu yosiyanasiyana mankhwala pa Kuyamwitsa ndi chifukwa chakuti pophika yogwira likulowerera mu mkaka wa m'mawere ndi akhoza kulowa mu thupi la mwana, omwe ndi owopsa pa nkhani ya kulandira ndalama sanagaŵiridwe makanda. Kukonzekera "Genferon Kuwala" (kutsitsi) kuti mkaka wa m'mawere angagwiritsidwe ntchito chifukwa chiyani mkatikati selo chotchinga mammary zopangitsa. Tikawonetsetsa, kukondoweza kwa asilikali oteteza mayi kungotchula bwino chitetezo cha m'thupi ndi mwana. Komanso, ngakhale mankhwala "Genferon" mu mawonekedwe a kutsitsi ana pansi 14 simungathe kuziona (yekha chifukwa "wamkulu" dosing), suppositories munali mankhwala amaloledwa kugwiritsa ntchito kwa nthawi neonatal pamene matenda osiyanasiyana tizilombo.

mbali zotsatira

madokotala ambiri amalangiza ngati njira muyeso "Genferon Kuwala" (kutsitsi). Malangizo ntchito osati kuona zotsatira zenizeni mbali ku ntchito yake. Nthawi zina kumachitika zodabwitsa kuti zikusonyeza mtundu uliwonse wa interferon alfa-2b, anaonetsa kuzizira, malungo, kutopa, kusowa chilakolako minofu ndi mutu, thukuta. zotsatira ngati izi zimachitika makamaka pa kayendetsedwe pa 10000000 IU patsiku. Nthawi ya linachepa amafuna kufunsa dokotala kusankha mankhwala ena mankhwala a.

Ngakhale ndi medicaments ena

Mokhudzana ndi mogwirizana ndi zinthu zina "Genferon Kuwala" mankhwala (m'mphuno kutsitsi) pa ntchito malangizo sapereka malangizo zambiri. Ndi mawonekedwe mlingo ali n'zogwirizana ndi pafupifupi zonse mankhwala. Chokha n'kosavomerezeka munthawi yomweyo utsogoleli wa mphuno madontho anafuna kulimbana njira catarrhal mu m'mphuno ndi mankhwala, zimenezi zimachititsa mogwira awo. Choncho, ntchito mankhwala ayenera gulu, kutsatira mfundo za utsogoleli osiyana.

Reviews

odwala ambiri ankachitira ndi mankhwala "Genferon Kuwala" (kutsitsi), kunena za nchito zake mkulu inhibiting matenda tizilombo ndiponso kusapezeka mavuto komanso nkhawa za ntchito zake. isanayambike oyambirira a ntchito (zizindikiro choyamba cha matenda) sangalepheretse kukula kwa matenda ndi kupondereza izo posachedwapa. Monga limodzi ndi chosowa cha kupanda mankhwala m'mphuno kwa ana osaposera zaka 14, monga mankhwala "Genferon Kuwala" gulu m'badwo uwu, monga tatchulazi, alipo yekha mu mawonekedwe a suppositories. Zimenezi zingachititse kukana mtundu uwu wa mankhwala odwala wamng'ono.

Choncho, kuoneka zizindikiro zilizonse za chitukuko fuluwenza kapena zina pachimake matenda kupuma akhoza amalangiza nthawi yomweyo ntchito yokonza "Genferon Kuwala" (kutsitsi m'mphuno), ndi mavairasi oyambitsa, popatsana m'thupi ndi modulating kanthu, ndipo wotsutsa-yotupa tingati umene kubisa zikuchitika matenda koyambirira ndi kuchotsa zizindikiro zonse akuwonetseredwa mu nthawi yochepa. Administration mankhwala kuti kuzilambalala dongosolo m'mimba chololera, kaya chakudya pa nthawi iliyonse, pa yemweyo yogwira pophika monga mmene tingathere mofulumira odzipereka mu malo jekeseni. Intranasal ntchito facilitates malowedwe a mankhwala mwachindunji ku malo a matenda (kotero monga matenda tizilombo zimafalitsidwa makamaka ndi m'malovu airborne), khama zotsatira zawo kwawoko ndi zambiri thupi lonse, lomwe ndi chifukwa mayamwidwe tsankho ya mankhwala mu m'magazi mwa nembanemba mucous a m'mphuno a chimachititsanso.