"Glibenclamide": malangizo ntchito, amasulidwe mawonekedwe, chithunzi, analogs

ndiwo mankhwala "glibenclamide" n'chiyani? Malangizo ntchito, mawonekedwe kumasulidwa, analogues komanso nkhani zokhudza zakayendesedwe ka nchito mankhwala zili m'munsimu.

Zikuchokera, ma CD, mawonekedwe kumasulidwa wothandizila

Mu mawonekedwe zimene anapanga mankhwala "glibenclamide"? Guide inanena kuti chida amapangidwa mu mawonekedwe a mapiritsi omwe anayikidwa mu makontena a pulasitiki (ndondomeko ya selo) ndi bokosi chidapangidwa kuchokera ku katoni, motero.

The zikuchokera mankhwala pansi kulingalira monga 5 mg glibenclamide ndi zosakaniza wothandiza monga mbatata wowuma, lactose monohydrate, magnesium stearate, sodium croscarmellose, enaake carmine E 132 colloidal pakachitsulo woipa 25, ndi povidone.

kanthu mankhwala

ndi mankhwala "glibenclamide" n'chiyani? Malangizo Ntchito limanena kuti izi zikutanthauza naonetsere zotsatira hypoglycemic anthu athanzi ndi odwala matenda a shuga a mtundu II.

Mphamvu ya mankhwala chifukwa umatha kuonjezera insulin katulutsidwe maselo pancreatic beta chifukwa kukondoweza awo. Malinga ndi akatswiri, amenewa mankhwala kumatheka mchikakamizo cha shuga.

Kayendedwe imachitika chiphunzitso m'kamwa

Kodi chalakwika khalidwe la pharmacokinetic mankhwala "glibenclamide"? Malangizo ntchito ananenetsa kuti pambuyo dosing m'kamwa mwa miyala ya mankhwala yogwira mofulumira ndipo pafupifupi atamezedwa kotheratu kwa mundawo m'mimba.

Munthawi yomweyo chakudya wambiri kumayambitsa kuchepetsa wa glibenclamide ndende mu madzi (poyerekeza ndi chopanda kanthu m'mimba). The kugwirizana chigawo ichi ndi albumin wa kuposa 98%.

Wodwalayo chiwindi glibenclamide ali n'kukhala metabolites zotsatirazi: 3-CIS-hydroxy-glibenclamide ndi 4-Trans-hydroxy-glyburide. Iwo linanena bungwe pamlingo ndi impso pamodzi ndi chimbudzi.

The zikutanthauza Kupha theka moyo wa mankhwala ndi maola 2-3.5. Mu anthu ndi mkhutu ntchito chiwindi, chithunzi ichi kwambiri yafupika.

Zikuonetsa ntchito mankhwala

Mu zina, mankhwala wodwala "glibenclamide" awerenge? Izi zikutanthauza amalangiza kutenga odwala matenda a shuga a mtundu II, pamene palibe kuthekera azilipira hyperglycemia okhwima zakudya ndi zinthu zolimbitsa thupi, kapena kuwonda.

Ziletso ntchito

Kodi pali contraindications mu mankhwala "glibenclamide"? Malangizo Ntchito limanena kuti malo suyenera kutumikiridwa odwala:

• amayaka yaikulu;
• Hypersensitivity ku chigawo yogwira, ndi diuretic thiazide kapena sulfonamides;
• ketoacidosis;
• ashuga chikomokere ndipo limati prekomatosnoe;
• chitukuko cha hypoglycemia;
• opaleshoni ndi zoopsa zina;
• gastroparesis ndi kutsekeka m'matumbo;
• mimba;
• shuga mtundu woyamba;
• yoyamwitsa.

Medicament "glibenclamide": malangizo ntchito

Akuti mankhwala ayenera kuperekedwa pokhapokha ndi dokotala wodziwa. Izi mankhwala nthawi zonse pamodzi ndi zakudya kwambiri. Only mu nkhani iyi zidzakhala zothandiza. mlingo umadalira pa zotsatira mtima mayeso (shuga, zizindikiro anachokera ku mkodzo, etc.).

Choncho mmene kutenga mankhwala "glibenclamide"? Therapy izo zikutanthauza kuyamba ndi Mlingo kochepa. Zimenezi ndi zoona makamaka kwa anthu ndi chizolowezi hypoglycemia ndi thupi osachepera makilogalamu 50.

Childs, mlingo woyamba wa medicament ndi 0,5-1 piritsi patsiku. Izi limafanana 2.5-5 mg wa yogwira pophika. Pamene inefficient kanthu mankhwala mwachindunji chiwerengero akhoza pang'onopang'ono kuchuluka kwa mapiritsi atatu pa tsiku, lolingana mg wa 15 wa yogwira pophika. Izi zichitike pa intervals wa masiku ochepa kuti sabata limodzi, mpaka mukufuna zimatheka.

Kodi kusamutsa wodwalayo mankhwala wina mu mankhwala "glibenclamide"? Kugwiritsa ntchito mankhwala mu nkhani iyi ayenera kuchitidwa ndi kusamala kwambiri. Choyamba, wodwala Kwalamulidwa mapiritsi maola 0.5, ndiyeno pang'onopang'ono kuwonjezera mlingo kuti ikhale yopambana.

odwala Okalamba ndi debilitated kapena odwala ndi kuperewera kwa zakudya m'thupi ndi mkhutu chiwindi ndi impso ntchito zogwiriziza kapena mlingo woyambilira wa mankhwala wokha kuchepetsa mosavuta chitukuko cha hypoglycemia. Komanso kusankha pa mlingo woyenerera wa mankhwala mankhwala ayenera kukhala ndi kucheperachepera thupi kapena pamene kusintha njira yake chikhalidwe moyo.

njira A kulandira hypoglycemic piritsi

Kodi kugwiritsa ntchito mankhwala "glibenclamide"? Malangizo ntchito (chithunzi cha mankhwala ndi m'nkhani ino) limanena kuti ankaona piritsi ayenera kumwedwa pamaso chakudya ndi madzi osasankhidwa ndi wopanda kutafuna.

Pa mlingo tsiku la mapiritsi 2, izo tikulimbikitsidwa kugawanitsa medicament mu 2 Mlingo kugawidwa (m'mawa ndi madzulo) mu chiŵerengero cha 2: 1.

Nkofunika kwambiri kuti ntchito mankhwalawa nthawi yomweyo. Kusiya phwando piritsi chiphunzitso choletsedwa anatengedwa pamodzi ndi zotsatirazi.

Kutalika kwa mankhwala zimadalira chida ichi matenda. Kuyambira chithandizo chofunika kuchita polojekiti mosalekeza wa boma la zinthu kuwombola wodwalayo.

zotsatira zoyipazi

The medicament "Glibenclamide" analogs amene ali m'munsiwa angachititse chitukuko cha zochita osafunika okhudza mantha, endocrine, zotumphukira ndi m'mimba machitidwe ndi hematopoietic. Pa nkhani imeneyi, wodwala akhoza kusonyeza zizindikiro chowawa monga nseru, hypoglycemia wa kusinthasintha mwamphamvu, kwa chiwindi kukanika, kutsekula m'mimba, mutu, cholestasis, kufooka, chizungulire komanso kutopa.

Iwo ayenera kukumbukira kuti zakudya za chida si kukusalani maonekedwe a zochita dermatological ndi matupi awo sagwirizana monga photosensitivity, kuyabwa, zotupa pa khungu ndi zizindikiro zina zosasangalatsa.

Nthawi ambiri osokoneza hypoglycemic wothandizila

Kodi zizindikiro zikayamba pamene apamwamba Mlingo wa mankhwala "glibenclamide"? limati Manual kuti ambiri osokoneza, wodwala angathe hypoglycemia, mwina limodzi ndi kufooka, kumverera njala, mutu, nkhawa, thukuta kwambiri, chizungulire, minofu kugwedeza, palpitations, kutupa ubongo, masomphenya ndi mawu matenda a.

Chithandizo cha zinthu zimenezi zimafuna mwamsanga chikuonetseratu shuga-zidyeke chakudya. Mwachitsanzo, madzi zipatso, shuga, chimanga madzi, wokoma otentha tiyi kapena uchi.

Zikavuta kwambiri, wodwalayo chikuyendetsedwera 50% shuga njira, "Dextrose" "Glucagon" kapena "Diazoxide". Komanso amafuna ulamuliro wapadera wa glycemia, creatinine, urea asafe, electrolytes ndi kudziwa pH.

Mogwirizana ndi njira zina zachipatala

Kuphatikiza mankhwala ankaona ndi mankhwala odana zokhudza zonse, tetracyclines, fluoroquinolones, chloramphenicol, Mao zoletsa, ndi Ace, H2-blockers, "clofibrate" beta-blockers, probenecid, bezafibrate, "paracetamol", anabolic mankhwala, ethionamide, allopurinol, pentoxifylline, cyclophosphamide "reserpine", insulin ndi sulfonamides amatha potentiate hypoglycemia.

Pamlandu ntchito mankhwala ndi phenothiazines, chithokomiro ndi glucocorticoid mahomoni, barbiturates, estrogens, diazoxide, progestins, glucagon, salt lifiyamu, Adrenomimeticalkie zikutanthauza saluretikami nicotinic acid ndi ena ofanana angatilepheretse zotsatira zake hypoglycemic.

formulations oterowo acidified mkodzo (kuphatikizapo mankhwala enaake ammonium, calcium enaake, ascorbic acid), amatha kukulitsa ntchito ya medicament ankaona.

Ntchito "glibenclamide" ndi "rifamycins" Iyamba inactivation ndi kuchepetsa mphamvu ya zakale.

tsatanetsatane

wothandizila Hypoglycemic tiyenera kuziganizira mosamala kuti odwala matenda kukanika aimpso ndi chiwindi, komanso pathological mabele ndi zopangitsa adrenal, zinthu febrile ndi uchidakwa aakulu.

Kuti akwanitse mankhwala yachibadwa amafuna polojekiti zonse misinkhu shuga m'magazi a wodwala, komanso excretion ake.

Ngati zakudya mankhwala wodwala akufotokozera hypoglycemia, shuga yoikidwiratu mkati (mu ngati munthuyo amadziwa). Ngati wakomoka, shuga ndi kutumikiridwa m'nsinga, ndi glucagon - subcutaneously, intramuscularly kapena kudzera m'mitsempha. Pambuyo wodwala n'kudzuka, nthawi yomweyo kupereka chakudya, wolemera mu chakudya, pofuna kupewa ndi zisadzachitikenso wa hypoglycemia.

Mtengo ndi analogues (ofanana) Njira

Select analogs za mankhwala ayenera kukhala odziwa akatswiri. Madokotala monga mankhwala zotsatirazi: "Manin", "Manin", "Maniglid", "Betanaz" ndi "Antibet".

Iwo ayenera kukumbukira kuti pharmacies zambiri kugulitsa ofanana matanthauzo chida. The ntchito ambiri iwo, "Glidanil", "Glibeks", "Glibamid", "Gilemal", "Glibomet", "glibenclamide". Mlingo wa ndalama izi amasankhidwa payekha.

Koma mtengo "glibenclamide" mankhwala, izo zimasiyanasiyana mu osiyanasiyana 280-360 rubles.

Ndemanga za mankhwala

Tsopano inu mukudziwa kuti ndi mankhwala "glibenclamide". Malangizo ntchito, ndi mawonekedwe a analogues njira tafotokozazi.

Zimene akunena za ogwiritsa izi mankhwala? Monga ulamuliro, mauthenga zonse za izo ndi kuchepetsedwa kuti mudziwe za anthu kapena regimens ena achire kuti analimbikitsa anthu odwala matenda a shuga.

Ogula kuti nthawi zambiri "glibenclamide" kugwiritsidwa ntchito ngati monotherapy a. Ngakhale pali odwala amene ali chinafotokoza mankhwala limodzi ndi mankhwala ena hypoglycemic.

Malingana ndi madokotala, poika mankhwala pansi kulingalira amafuna munthu njira. Pankhaniyi, katswiri ayenera kukhala bwino ndi zotsatira zonse za kufufuza, ndi maphunziro ena. Tengani "glibenclamide" odwala nzeru zawo ndi woopsa kwambiri thanzi ndi moyo.