"Komfoderm": malangizo ntchito, maonekedwe, zikuchokera, analogs ndi ndemanga

Kodi mukudziwa za kukonzekera monga "Komfoderm"? Malangizo ntchito, mtengo, ndemanga, komanso analogs ndi makhalidwe ambiri a mankhwala amadziwika ochepa. Choncho, m'nkhani ino, tinaganiza imfomeshoni zonse za mankhwala.

Fomu, zikuchokera ndi kufotokozera

Kukonzekera "Komfoderm", malangizo ntchito yomwe tifotokoze, opangidwa mu mawonekedwe a kirimu woyera ndi fungo (angakhale opanda ndipo ndi kirimu kulocha).

The zigawo zikuluzikulu yogwira wothandizila izi kwa ntchito apakhungu ndi atseponat methylprednisolone ndi urea. Komanso mafuta mankhwala ndi zosakaniza wothandiza amene anapereka monga paraffin madzi, propylene glycol, polysorbate 80, carbomer interpolymer (mtundu A), trometamol, metipparagidroksibenzoata ndi madzi oyera.

mankhwala

ndi mankhwala m'dera "Komfoderm" (kirimu) chiyani? Malangizo ntchito akusimba kuti glucocorticosteroid ndi wothandizila keratolytic imodzi. Zimenezi ndi chifukwa peculiarities wa zigawo m'gulu kapangidwe kake. Taganizirani mwatsatanetsatane katundu wawo.

Methylprednisolone aceponate - izi si halogenated kupanga steroid. Ntchito panja, ndi waluso mwa kupondereza thupi lawo siligwirizana ndi yotupa khungu komanso zochita amene amagwirizana ndi kuchuluka kuzikonzanso. kukhudzana kotero kumatsogolera ku kuchepetsa kwambiri zizindikiro cholinga cha kutupa (erythema, edema, zilowerere) ndi zomverera zotengera malingaliridwe (kuyabwa, kuyabwa, kupweteka, etc.).

Sitingathe kunena kuti ntchito mankhwala pa mlingo zotsatira zake zokhudza zonse pa thupi kochepa.

Pambuyo ntchito nthawi ndi mobwerezabwereza methylprednisolone aceponate pa pamalo lalikulu khungu (40-60%), komanso imposition yake pansi Mavalidwe occlusive odwala mwaonapo monyanyira mu zopangitsa kwa adrenal, kuphatikizapo milingo osati adasandulika tochepa.

Thunthu mu funso anatha kum'manga kwa maselo glucocorticoid okhudza maselo ambiri, kuchititsa zosiyanasiyana zotsatira kwachilengedwenso. Makamaka, ndondomeko zimenezi zimapangitsa kuti mankhwala kupatsidwa ulemu macrocortin kaphatikizidwe. Mu zathera kumabwezera mmbuyo arachidonic asidi kumasuka ndi mapangidwe owayimira yotupa ngati leukotrienes ndi prostaglandins.

Kodi anachita yokonza urea "Komfoderm"? Malangizo ntchito limanena kuti chigawo zimenezi zimakhudza hydrating ndi keratolytic. Izo zikuwamanga madzi, potero pokonza ndi stratum corneum amalimbikitsa khungu.

Kuwonjezera kanthu keratolytic, urea ndi zinaonetsedwa pa chionetserocho ntchito proteolytic.

kinetics

Kodi kirimu ndi odzipereka, "Komfoderm"? Malangizo ntchito ananenetsa kuti pambuyo ntchito chida methylprednisolone aceponate hydrolyzes pafupifupi nthawi yomweyo mu dermis ndi khungu.

The yogwira kwambiri ndi metabolite waukulu wa mankhwala ndi 6alfa-methyl-prednisolone 17 propionate.

Mlingo wa dermal mayamwidwe mankhwala zimadalira boma amawaona integument anthu ndi njira zake ntchito (wokhala kapena wopanda occlusive bandeji).

Percutaneous mayamwidwe wa mankhwala anthu ndi psoriasis ndi atopic dermatitis ndalama pafupifupi 2.5%, lomwe ndi pang'ono pamwamba pa mlingo mu odzipereka wathanzi (za 0.6-1.5%).

Pambuyo kukhudzana 6alfa-methylprednisolone 17-propionate mu magazi zokhudza zonse akukhamukira izo conjugated acid glucuronic m'malo mofulumira, ndiye kenako inactivated.

Metabolites njira mwaganizapo inathetsedwa makamaka kudzera impso pambuyo maola 16. The yogwira zosakaniza mankhwala si cumulate mu chamoyo. Chifukwa cha absorbability otsika a urea ndi ntchito apakhungu a kirimu imabwera zotsatira zokhudza zonse negligible.

umboni

Kuyambira pamenepo anaika "Komfoderm" (kirimu)? Malangizo ntchito lili mndandanda wa zizindikiro:

• tating'onoting'ono chikanga;
• matupi awo sagwirizana dermatitis (kukhudzana);
• neurodermatitis, atopic dermatitis;
• chikanga woona;
• yosavuta kukhudzana dermatitis;
• disgidroticheskaya chikanga.

M'mawu ena, mankhwala amenewa anasonyeza matenda yotupa dermal, soprovozhdayuschihesya keratinization wachisokonezo, komanso naonetsere tilinazo mkulu mankhwala ndi glucocorticosteroids apakhungu.

contraindications

Mankhwala "Komfoderm" malangizo ntchito zomwe zikufunika kuwerenga odwala onse, osati ntchito mu:

• Hypersensitivity nyengo ya zonona;
• TB kapena njira chinzonono mu mafunsidwe a medicament;
• matenda tizilombo (kuphatikizapo varicella, nsungu zoster);
• rosacea, perioral dermatitis kutsatira mafuta;
• mtundu uliwonse wa katemera;
• akaziwo anali ana aang'ono.

Medicament "Komfoderm" (mafuta): malangizo ntchito

Price malipoti wothandizila ndi za 480-530 rubles. Mankhwala umagwiritsidwa ntchito m'madera akhudzidwa khungu ndi wosanjikiza woonda, kamodzi patsiku.

Kutalika kwa mosalekeza tsiku ndi tsiku chithandizo ndi kirimu siziyenera upambana masabata 12. Tikumbukenso kuti mankhwala a zotupa ayenera idzachitika kwa masiku 5.

zotsatira zoyipazi

Zotani mwachibadwa zingachititse mankhwala "Komfoderm m2"? Malangizo malipoti ntchito kuti mavuto amenewa n'zochepa kwambiri. Iwo zimakhala mu mawonekedwe a zotsatirazi zosiyanasiyana m'dera: kuyabwa, erythema, moto kutengeka, mapangidwe totupa vesicular.

Zikatero, ngati medicament ntchito koposera masabata anayi, kapena m'madera ambiri mwa khungu, wodwala angathe khungu manja kapena telangiectasia kuwoneka akneformnye kusintha, zizindikiro Tambasula ndi zotsatira zokhudza zonse, amene amayamba ndi mayamwidwe corticosteroid lapansi.

Nthawi zina ankaona mankhwala amachititsa hypertrichosis, folliculitis, depigmentation wa khungu, perioral dermatitis, ndipo thupi lawo siligwirizana.

Ogula ndemanga analogues "Komfoderma"

okha kirimu "Advantan" amatanthauza analogs za mankhwala.

Anthu Kodi kunena za "Komfoderm" odwala mafuta? Malinga ndi mayankho awo ndi medicament mu funso ndi othandiza kwambiri njira m'deralo. tanthauzo lake amalola kuti tichotse matenda osiyanasiyana khungu, kuphatikizapo chikanga, neurodermatitis, ndi dermatitis. Nthawi zina, mankhwala ntchito ngakhale mu psoriasis.

The kuipa kwa "Komfoderm" mafuta monga mtengo wake mkulu, komanso kulephera kugwiritsa ntchito ana.