Mankhwala "Chlorpromazine": ndemanga madokotala, malangizo ntchito, zikuchokera ndi kufotokozera

Antipsychotic mankhwala - ndi mankhwala psychotropic, amene cholinga zochizira matenda psychotic. Tikumbukenso kuti dzina mwambo wa mankhwala - neuroleptics. Mankhwalawa angathandize kusonkhezera zizindikiro monga zinyengo, Musanyengedwe, kuyerekezera zinthu m'maganizo, ndinaganiza chisokonezo psychotic mukubwadamuka, khalidwe matenda , ndi zina zotero. D. Perekani mankhwala akhoza anakumana dokotala.

Wotchuka kwambiri antipsychotic mankhwala amachita "Chlorpromazine". Malangizo ntchito, mtengo, ndemanga, analogs, contra zizindikiro ndi mankhwala omwe anapereka m'munsimu.

Zikuchokera, maonekedwe, mawonekedwe

mawonekedwe Kodi chibadidwe mankhwala "Chlorpromazine"? Malangizo, ndemanga amanena kuti mankhwala chogulitsidwa mawonekedwe a mapiritsi wooneka pinki, komanso njira yothetsera makonzedwe mtsempha ndi mu mnofu. Thunthu yogwira amatanthauza deta ndi chlorpromazine hydrochloride. Komanso, malingana ndi mtundu Atatulutsidwa muli zosiyanasiyana zowonjezera.

mbali pharmacological

ndi chidwi mankhwala "Chlorpromazine" n'chiyani? Malangizo ntchito, mayankho amasonyeza kuti ndi wothandizila antipsychotic imene gulu lake pharmacological amatanthauza neuroleptics. Iwo ali hypotensive, antiemetic ndi zotsatira a antihistamine.

The yogwira pophika mankhwala ndilochokera ku phenothiazine. Kuwonjezera katundu izi yogwira medicament nazo sedative, hypothermic ofooka, antipsychotic, akutivutitsa m'deralo, vasodilating ndi zotsatira amtengo M-anticholinergic.

Antipsychotic zotsatira za chida zimatheka ndi kutsekereza dopamine D ₂ zolandilira ndi machitidwe mesolimbic Mesocortical. Chifukwa katundu ngati mankhwala akhoza kuthetsa kuyerekezera zinthu m'maganizo, zinyengo ndi zizindikiro zina lokhalamo maganizo.

Tikumbukenso kuti "Chlorpromazine", ndemanga zimene zili m'munsimu, relieves zosiyanasiyana psychomotor mukubwadamuka, ndewu ndipo kumachepetsa kusalekerera mantha psychotic.

Sedative zotsatira za mankhwala zimatheka ndi kutsekereza adrenergic reticular mankhwala kuti zili brainstem lapansi.

katundu wa mankhwala

ndi katundu wa chibadidwe mu medicament "Chlorpromazine" n'chiyani? Reviews onena kuti mankhwala kumafooketsa pa zowongolera ntchito reflex, pansi minofu chigoba, amachepetsa mowiriza galimoto ntchito, kuchepetsa tilinazo zikuchitika amkati ndi exogenous ndi malingaliro odekha. Ntchito mlingo waukulu wa mankhwala amachititsa kugona kwambiri.

Anatseka misewu ya mitsempha vagus mu m'mimba thirakiti dopamine _D2 zolandilira ili mu emetic zone choyambitsa ndi pakati amapereka zotsatira antiemetic mankhwala. Iwo ayenera kukumbukira kuti malo uyu anali kwenikweni zolandilira M-cholinergic. Komanso, zotsatira zake kutchulidwa anati kwa maselo alpha-adrenergic.

Zochita za mankhwala

mankhwala "Chlorpromazine" Kodi ntchito? Reviews kuti chida ichi amatha kwathunthu kuthetsa mavuto kuti ankayambitsa ndi wa epinephrine wa. Zotsatira zake hypothermic chifukwa anatseka misewu ya maselo dopamine kuti zili ubongo imene imalamulira kutentha kwa.

Ankaona mankhwala Sachita magazi, kugunda kwa mtima ukuwonjezeka, ali ofooka antihistaminic zotsatira ndipo anasonyeza kataleptogennoe kanthu, komanso amachepetsa permeability a mpanda capillary.

Pakuti makonzedwe mu mnofu wa medicament amachititsa sedation nthawi ¼, ndipo pambuyo makonzedwe m'kamwa - Mphindi pambuyo 120. Wodwala wololera kwa sedative ndi hypotensive zotsatira akufotokozera pakatha mlungu umodzi.

Pamene mwalandira mankhwala mu katundu wake antipsychotic zimakhudzanso tsiku 4 kapena 7. Zotsatira achire mankhwala kumatenga za 2-6 miyezi.

The pharmacokinetics mankhwala

Kodi "Chlorpromazine" mawere? Reviews inanena kuti pakamwa chlorpromazine kudya koma osati kwathunthu odzipereka kwa dongosolo m'mimba. Wake woipa pachimake magazi akwaniritsa pambuyo 4 h.

Izi mankhwala amaloŵamo woyamba kudutsa chiwindi. Choncho ndende yake mu magazi pambuyo makonzedwe m'kamwa ndi zochepa kwambiri kuposa ndende pambuyo makonzedwe mu mnofu.

mankhwala ndi zimapukusidwa mu chiwindi ndi ena ofanana wofooka ndi akuchitachita.

Chlorpromazine ali ndi chomangira mkulu mapuloteni plasma. Iwo inafalitsidwa mu thupi la wodwalayo, ozama mwa BBB.

Theka moyo mwa mankhwala yogwira mankhwala ndi mphindi 30.. Choncho Kupha ena ofanana kungakhale yaitali.

Anasonyeza medicament ankaona pamodzi ndi mkodzo ndi ya ndulu.

Mankhwala "Chlorpromazine": zikuonetsa ntchito

Reviews onena kuti mankhwala chimagwiritsidwa ntchito mchitidwe bongo. Iwo Kwalamulidwa mankhwalawa mukubwadamuka mwa munthu akuchita misala. Komanso, mankhwala ntchito aakulu psychosis, pachimake limati onyenga, hypomanic chisangalalo tulo, psychopathy, maganizo matenda, nkhawa, mantha ndi nkhawa.

Kuwonjezera zinthu zomwe zalembedwa zikuonetsa ntchito mankhwala awa: kulimbikira hiccups, mowa psychosis, osamvera kusanza, nseru kwambiri. Ngati pali ululu mankhwala timapitiriza zotsatira za analgesics.

Iwo ayenera kukumbukira kuti njira anatumizidwa m'nkhani matenda amene anatsagana ndi kuchuluka kamvekedwe akulu, kafumbata (monga kuphatikiza mankhwala molumikizana ndi barbiturates) ndipo pambuyo chisokonezo osiyana mu makope ubongo.

Si kale, izi mankhwala ntchito yokumba hypothermia anapeka zosakaniza lytic. Mu opaleshoni mankhwala zambiri analamula kuti sedation ndipo ambiri ochititsa dzanzi potentiation.

Mu dermatological mchitidwe "Chlorpromazine" (mayankho odwala za mankhwala makamaka khalidwe abwino) ntchito kuyabwa dermatoses. Komanso, angagwiritsidwe ntchito pa matenda a khalidwe pachimake porphyria.

contraindications

Nthawi zina, osati Kwalamulidwa antipsychotic "Chlorpromazine"? Reviews madokotala amanena kuti chida ichi si ntchito limati comatose zochokera kwina kulikonse, komanso odwala ndi kuponderezedwa aakulu ya ubongo, matenda aakulu mtima ndi mtima tsankho kwa mankhwala yogwira ntchito yanthaŵi matenda a ubongo ndi msana zokhudza zonse chikhalidwe cha ubongo, anam'peza zotupa pa mundawo m'mimba ndi pa chifuwa kudya.

Polingalira za chiopsezo cha zochita hepatotoxic, zikutanthauza akuchipatala ndi kusamala kwambiri chidakwa. N'chimodzimodzinso ndi khansa ya m'mawere, magazi dyscrasias, hyperplasia ku prostate, khungu, anatseka kwambiri, matenda Parkinson, khunyu, myxedema, kusanza, cachexia, syndrome Reye ndi okalamba.

Mankhwala "Chlorpromazine": malangizo ntchito

Mapiritsi mavoti amene anapereka hereinafter, ntchito mchitidwe Psychiatric poyambitsa tsiku mlingo wofanana 25-100 mg. ndalamazo lagawidwa Mlingo 1-4. M'kupita kwa nthawi, kuwonjezera mlingo uliwonse masiku anai 25 kapena 50 mg kukwaniritsa zotsatira ankafuna.

Ndi nkhawa preoperatively yogwira kumwa mankhwala kwa maola 2-3.

The pazipita umodzi mlingo wa wothandizila izi ndi 300 mg, ndi tsiku - 1,5 ga

Pankhani njira, ndi kutumikiridwa m'nsinga kapena intramuscularly. Koyamba mlingo wa mankhwala ndi 25-50 mg.

Pamaso utsogoleli wa mankhwala izo kuchepetsedwa ndi 2.5 ml ya yothetsera sodium kolorayidi kapena procaine. Majekeseni kuchita kwambiri jekeseni mu mnofu.

The pazipita umodzi mlingo wa wothandizila izi ndi 150 mg ndi tsiku - 1 g Koma makonzedwe mtsempha, mfundo izi zizigwirizana 100 ndi 250 mg.

zotsatira osafunika

Kuchititsa zovuta zilizonse "Chlorpromazine" (mapiritsi)? Reviews onena kuti magawo oyambirira mankhwala mankhwala zingachititse pakamwa youma, paresis wa malawi, frigidity, kuchuluka tulo, kudzimbidwa, matenda tulo, chizungulire, mkhutu kudya, tachycardia, anasonyeza mtundu wa orthostatic hypotension, posungira mkodzo, yafupika potency, ziwengo ndi kugwa magazi.

mankhwala yaitali ndi mankhwala amachititsa minofu omangana khosi ndi lilime, neuroleptic maganizo Akinetes-okhwima chodabwitsa, matenda extrapyramidal, amenorrhea, akathisia, anachedwa anachita zikuchitika zosiyanasiyana, hypercoagulability, kusanza, kusintha kaganizidwe, mtima arrhythmia, mtundu wa khungu, chopinga wa mafupa hematopoiesis , gynecomastia, cholestatic matenda a chikasu ndiyo, galactorrhea, giperplolaktinemiyu, oliguria, kutsegula m'mimba, ndi neuroleptic matenda oopsa. Ndi mtsempha kulowetsedwa phlebitis zinapangidwa mu mnofu - infiltrates.

ayamikira yeniyeni

Therapy chida amafuna ulamuliro mosamala magazi, zimachitika, machitidwe a impso ndi chiwindi.

mankhwala Zimenezi zingachititse photosensitivity, choncho pa nthawi ya anavomereza bwino kupewa kukhudzana.

Analogs ndi mtengo

Mtengo wa mankhwala zimadalira mtundu kumasulidwa. Kenaka Mbale 10 zikhoza kugulidwa kwa 60 rubles, pamene ena ochuluka chimodzimodzi miyala ndi pafupifupi 150 rubles.

Ndi analogues za mankhwala monga "Chlorpromazine hydrochloride" ndi "Tisercinum".

Reviews

Akatswiri ankaona medicament ali amphamvu antipsychotic tingati kuchotsa zizindikiro zonse za psychomotor mukubwadamuka. Komabe, tisaiwale kuti izi zikutanthauza ndemanga ndi zachilengedwe zosiyanasiyana.

Odwala ena amati mankhwala othandiza mu Alzheimer matenda, misala, psychosis, khunyu, ndi bwino relieves nkhawa ndi nkhawa. Ena ogula amakhulupirira kuti ankaona mankhwala amakwiya chitukuko cha khunyu khunyu, dzanja kugwedezeka, matenda umunthu zosiyanasiyana ndipo kwambiri tulo boma.

Mulimonsemo, mankhwala uyu ayenera kugwiritsidwa ntchito pokhapokha ngati anafuna ndi kuyang'aniridwa ndi dokotala nawo.