Mankhwala "Fluorouracil": malangizo ntchito, maonekedwe, zikuchokera, analogs ndi ndemanga

Cancer, mwatsoka, pali tsopano zambiri. Mwachibadwa, sitingathe m'mbuyo, tiyenera kulimbana matenda. Mulimonsemo sayenera ankachitira paokha. Popanda thandizo akatswiri ndi chofunika kwambiri. chakuti mankhwala ena akhoza zotchulidwa mankhwala ndi ntchito kokha pa kamwedwe wapadera. Nthawi zambiri, madokotala mankhwala mankhwala monga "Fluorouracil". Malangizo ntchito mankhwala chidzamasulidwa zotero hereinafter.

makhalidwe General

Choncho, anapereka mankhwala ntchito Oncology, ngati ali odana ndi chotupa tingati. Iwo akhoza kukhala m'gulu antimetabolite lapansi. Ndi, mankhwala ali madzi, akhoza kwambiri m'mbuyo kuwombola zinthu pakati pa maselo.

"Fluorouracil" (malangizo ntchito nthawi zonse mmatumba ndi mankhwala) ali ndi dongosolo losavuta. Pamafunikanso madzi wosabala ndi hydroxide ndi sodium. Koma chachikulu chigawo yogwira ndi fluorouracil.

mitundu kumasuka ndi mbali ya mankhwala

Tikumbukenso kuti mankhwalawa ali ndi njira zosiyanasiyana. Ngati mukufuna kuti, "Fluorouracil" malangizo Buku limanena za mtundu ngati:

1. A njira amadzimadzi makonzedwe mtsempha kapena intracavitary. nthawi zambiri zimachitika TH amadzimadzi 5% osakaniza 5 ml ampoules. Palinso njira kuikapo maganizo amene aikidwa mu 10 ml botolo.

2. mafuta. Ndi zambiri 5% ya TH. Iwo amagwiritsidwa ntchito pofuna kuchiza matenda a pakhungu, mwachitsanzo, Basile.

Ngati inu aikidwa monga "Fluorouracil" malangizo Buku muli mfundo zotsatirazi zokhudza madera phwando:

- Tsiku lililonse kulandira 0.5 g / m. kapena 12 mg / kg. mankhwala si masiku oposa 5. Pambuyo kuti ayenera mwezi umodzi yopuma.

- masiku kamodzi 7 0,6 g / m. Inde mankhwala ndi za 6-10 masabata.

- Mothandizana ndi mankhwala ena anticancer - 1st ndi tsiku 8 cha njira ya 0,6 g / m.

Komabe, m'zochitika zonse, mlingo ndi njira ya utsogoleli wa mankhwala Kwalamulidwa payekha. Izi zidalira pa zovuta ndipo siteji ya matenda, boma onse wodwala, thanzi lake komanso dongosolo mankhwala amphamvu.

Madzi angathe kuperekedwa bolus kapena kulowetsedwa. Kumbukirani kuti mankhwala ena zimene zimapatsidwa kwa wodwala molumikizana ndi ichi, kupereka kuchepetsa fluorouracil mlingo ndi 20-30%.

Zotsatira pharmacological ndiponso zimene ankachita ndi mankhwala ena

Choncho, "Fluorouracil" (malangizo ntchito, ikulongosola za kukonzekera ayenera kuwerenga ndi wodwala) amapereka odana ndi yotupa kwenikweni ndipo kwambiri kubweza mankhwala zimene anthu omwe amalimbikitsa kugawikana kwa maselo zilonda. Ndiko kuti, midadada mankhwala mapangidwe DNA.

Suction zikutanthauza msanga, kupanga ftoruridinmonofosfat. Iwo lamamatira mu chiwindi pafupifupi 20 maola. Kusiya kupuma kuchulidwa (60-80%) ndi impso (7-10%, zikutsatiridwa).

Ngati muyenera "Fluorouracil" malangizo Buku (mbali ya mankhwala, Takambirana kale) limanena kuti pali zinthu zina zimene si pamodzi ndi iwo. Mwachitsanzo, mankhwala a sulfa mankhwala, ndipo phenylbutazone ali osayenerana ndi anati njira. Koma alpha-interferon ndi cytotoxic wothandizila M'malo mwake, kuwonjezera zotsatira za "Fluorouracil". Kuyenera n'komwe poika mlingo.

Onani kuti katemera wa mtima, chifukwa dongosolo lake wofooka chitetezo ayenera ikuchitika osati kale kuposa miyezi 3 - chaka.

Zikuonetsa ntchito

Ngati inu mukusowa "Fluorouracil", malangizo ntchito (mankhwala mtengo pafupifupi 3000-3990 rubles) limafotokoza nkhani ya zinthu izi mankhwala:

• Cancer wa woonda kapena rectum, kum'mero ndi m'mimba. Choncho ngakhale pamene mankhwala zapatsidwa gawo kapena metastases unresectable.
• Pulayimale khansa chiwindi.
• matenda zilonda za ndulu, n'kuwasanganiza, m'mawere, chiberekero.
• Khansa ya zopangitsa kwa adrenal.
• Khansa ya prostate chotupa.
• Kartsinoz kapena khansa penile.
• Zotupa mu khosi ndi mutu.
• A chikhalidwe precancerous, ndi zotupa zazing'ono.

Umene mankhwala angagwiritsidwe ntchito ngakhale pamene zotupa mafangasi.

Kodi contraindications ndi kulibe?

Mwachibadwa, palibe kukonzekera mankhwala othandiza mofanana odwala ena onse. Pankhaniyi, nkhani ali ndi contraindications.

• Kwambiri mkulu ndi kudziwa zina zofunikanso pa chida.
• Mimba ndi mkaka wa m'mawere. Izi mankhwala ali zimakhudzanso poizoni kwambiri pa mwana wosabadwayo. Ngati phwando amasankhidwa pa yoyamwitsa, mwana bere-kudya.
• Chironda chachikulu matenda 12 mmatumbo chilonda kapena m'mimba, amene ali gawo pachimake.
• Aakulu magazi m'thupi ndi magazi pafupipafupi kuti zikhale zovuta kapena zosatheka kuti asiye (amapatsira mwana wake).
• Leukopenia.
• aimpso ntchito mkhutu kapena chiwindi.
• Health wodwalayo asanamwalire kwachilengedwenso.
• digiri amphamvu kwambiri za kutopa.

Komanso, pali zofooka. Mwachitsanzo, chisamaliro mankhwala mankhwala kwa anthu amene amadwala matailosi kapena katsabola. M'pofunika kupereka ulemu wapadera kwa woika mankhwala ngati wodwalayo kale kutenga cytostatics.

chingachitike mbali

Ngati muli Kwalamulidwa njira ya mankhwala monga "malangizo Fluorouracil-Lance 'ntchito mankhwala sasiyana kuchokera kale olembedwa. Funso kuti chidwi odwala ambiri, ndi mavuto. chakuti nthawi zina zingakhalenso zovuta kwambiri kuposa matenda palokha. Zotsatira Choncho, kulandira mankhwala zingaoneke mbali:

• Kuchepetsa chiwerengero cha leukocytes ndi maselo othandiza magazi kuundana m'magazi.
• Nosebleeds, lomwe ndi kusiya.
• Amaona masomphenya, diso mofulumira.
• Nseru, sipangakhalenso Ufumuyo kusanza ndi kutsekula m'mimba. Pankhaniyi, mankhwala ayenera inaimitsidwa kapena kusinthidwa.
• Chironda chachikulu.
• Stomatitis.
• Tsankho kapena okwana alopecia (dazi).
• Ischemic mtima kulephera, arrhythmia, angina, mtima kukanika, m'mnyewa wamtima infarction, cardiomyopathy, thrombophlebitis.
• Ululu ndi kuzungulira mutu, kuchuluka kupanga misozi, ndi kuopa kuwala, disorientation, imfa ya chikumbumtima kumva.
• Dysarthria.
• Kukoma, muzituluka magazi, kutentha, anorexia magwiridwe kwa chiwindi.
• Kufupika kwa mpweya, chifuwa, bronchospasm.
• Kuvutika mu ziwalo zoberekera: akazi - kusapezeka kwa msambo, amuna - azoospermia.
• hyperpigmentation wa khungu, dryness ndi akulimbana.
• Urticaria, zotupa dermatitis.
• Akulu kufooka ndi kujowina matenda osiyanasiyana.

Monga mukuonera, anapereka madzi kapena "Fluorouracil" mafuta malangizo Buku kuti muli bwino, mankhwala owopsa kwambiri. Komanso kafukufuku akusonyeza kuthekera amphamvu zotsatira toxigenic ndi carcinogenic mankhwala.

Zikhalidwe za mankhwala yosungirako

Kotero, inu alandira kale zambiri pa chitsanzo anagonjera. Tsopano tiyenera kuganizira makhalidwe a yosungirako ake. Kukhala "Fluorouracil" ayenera kukhala m'malo a mdima kwambiri. yosungirako kutentha ayenera kukhala madigiri 15-25. Kumene, mankhwala ayenera kusungidwa kuchokera ana sangawapeze. madzi amaundana si kwambiri analimbikitsa.

Alumali moyo wa mankhwala ndi zaka 2. Pambuyo atapita mankhwala sitingakhoze kutenga nthawi.

Pali nthawi zina pamene chitayiko akupezeka pansi Mbale wa. Izi zidzachitika yosungirako yaitali. Yesani kutenthetsa madzi 60 ° ndi kugwedeza wolimba. Kenako ozizira yachabechabe madigiri 35. Ngati precipitate kusungunuka ndipo madzi anayamba mandala kachiwiri Choncho, kukonzekera ndi wokonzeka ntchito.

analogues mankhwala

Chinthu chachikulu ndi zimene muyenera kudziwa asanadye "Fluorouracil" mankhwala - malangizo ntchito. Reviews kudzakhala zosafunika. Mupeza ina.

Ngati wodwala kutero kugula mankhwala, adokotala akhoza mankhwala analogues iye. Ali yemweyo yaikulu yogwira pophika - fluorouracil. Tsopano pali analogues wa mankhwala:

1. "Fluor-uracil."

2. "Efundeks".

3. "EPF-chikats."

4. "Fluoropleks".

5. "Fluratsil".

6. "ufa".

7. "Kveropleks".

8. "Timazin".

Reviews

Tikumbukenso kuti mankhwala amagwiritsidwa ntchito kwambiri. odwala ambiri inati mkulu efficacy polimbana ndi zotupa.

Komabe, iwo amati, ndi kuchuluka mavuto: nseru, kusanza, kupweteka kwa mutu, disorientation m'malere. Zimenezi n'zosadabwitsa, chifukwa mankhwala kwambiri poizoni.

Choncho, tazikonzeratu zambiri zokhudza mankhwalawa "Fluorouracil": malangizo ntchito, mtengo, ndemanga. Kumbukirani kuti umunthu mankhwala awa, musachite. Onetsetsani kuti dokotala. Mukatero pachiswe kufuna kudzipweteka kwambiri. The kwambiri kuti matenda zolondola zitha anapereka katswiri yopapatiza, pambuyo kafukufuku. Khalani wathanzi!