Mankhwala okonzekera "Valvir": madokotala a ndemanga

Kodi mankhwala a Valvir amagwira ntchito bwanji? Mukhoza kudziwa za mankhwalawa muzipangizo za nkhaniyi. Komanso, zimasonyeza zizindikiro zogwiritsira ntchito mankhwalawa, zotsatira zake, zotsutsana ndi zina zotero.

Kupangidwe, kuyika ndi mtundu wa mankhwala

Kodi kukonzekera "Valvir" ndi kotani? Ndemanga imanena kuti mankhwalawa angagulidwe ngati mawonekedwe oyera a mapiritsi oyera a biconvex, opangidwa ndi nembanemba ya film. Chinthu chogwira ntchito cha wothandizila ndi valaciclovir hydrochloride hydrate. Ma microcrystalline mapulosi ndi povidone amagwiritsidwa ntchito monga zigawo zowonjezereka za kukonzekera.

Pogwiritsa ntchito chipolopolo cha filimuyi, imakhala ndi giprolose, opadrai yoyera, titaniyamu ya dioxide, hypromellose ndi macrogol.

Mankhwala a "Valvir", omwe amawongosoledwa pansipa, akugulitsidwa m'makina opangidwa ndi aluminium ndi mapiritsi a PVC, omwe amaikidwa mu makhadi a makatoni.

Zochitika zamakono

Kodi katundu wa mankhwala "Valvir" ndi chiyani? Madokotala akunena kuti ichi ndi antibairusi. Kulowa mu thupi la munthu, valaciclovir imasinthidwa kukhala L-valine ndi acyclovir. Zimapezeka mothandizidwa ndi valacyclovirhydrolase.

Mankhwala omwe ali mu funso amasonyeza ntchito yowononga motsutsana ndi tizilombo to herpes simplex, varicella, cytomegalovirus, ndi zina zotero.

Acyclovir imatha kuchepetsa kaphatikizidwe ka mavairasi a DNA, komanso kutembenuzira acyclovir triphosphate ku mawonekedwe achangu. Thupi limeneli limalowetsedwa mu tizilombo toyambitsa matenda a DNA, omwe amachititsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda.

Pharmacokinetics

Mutatha kumwa mankhwalawa, valacyclovir imachotsedwa mwamsanga kuchokera m'magazi. Mlingo umodzi wa mapiritsi (0.25-2 g) ukufika pamtunda waukulu m'magazi mutatha maola 1-2. Pankhani iyi, mankhwalawa ndi 54 peresenti, mosasamala kanthu za zakudya zomwe amazidya.

Ubwenzi wa acyclovir kwa plasma ndi wochepa ndipo ndi pafupifupi 15%. Thupili limathamangitsidwa mofulumira kwambiri m'magazi onse. Zitha kupezeka m'chiwindi, impso, minofu ndi mapapo. Komanso, acyclovir imaloŵera mu cerebrospinal fluid, chinsinsi cha vaginja ndi zotsekemera.

Kwa anthu omwe ali ndi ntchito yambiri ya impso, theka la moyo wa mankhwalawa ndi maola atatu. Kuchokera kwa valaciclovir kumachitika ndi mkodzo.

Zizindikiro zogwiritsidwa ntchito

Kodi mukudziwa za cholinga chomwe mankhwalawa amatchedwa "Valvir" (mapiritsi)? Umboni wa akatswiri odziwa zambiri amadziwitsa za zotsatirazi:

• Herpes zoster;
• Mbira;
• Kuchulukanso kwa matenda a mucous membrane ndi khungu (kapewedwe ndi mankhwala), zomwe zimayambitsidwa ndi kachilombo ka herpes simplex (kuphatikizapo kachilombo ka HIV kamene kakangoyamba kumene);
• Matenda a Cytomegalovirus (prophylaxis) omwe anachitika panthawi yopanga thupi.

Komanso mankhwalawa amalembedwa kuti athe kuchepetsa matenda opatsirana pogonana a munthu wathanzi pa nthawi yogonana. Komabe, ziyenera kuthandizidwa ngati mankhwala oponderezana pamodzi ndi zipangizo zina zoteteza (makondomu, etc.).

Zotsutsana za ntchito

Kodi ndi nthawi ziti zomwe odwala salandira mankhwala a "Valvir"? Malangizo, ndemanga za madokotala amati zotsutsa izi:

• Kugwiritsira ntchito mafupa a mafupa;
• Kachilombo ka HIV;
• Zaka za ana;
• Kupatsirana kwa impso;
• Kuchulukitsa mphamvu kwa acyclovir, valaciclovir ndi mankhwala ena.

Pokhala ndi chisamaliro chapadera, mankhwala amaperekedwa kwa anthu omwe ali ndi vuto (makamaka m'mimba yapamwamba), impso kulephera, panthawi yomwe ali ndi pakati komanso pakamwa.

Valvir mankhwala: mankhwala othandizira

Maphunziro okhudza mankhwalawa, tidzakambirana pansipa.

Ndiyenera kutenga mapiritsi oletsa tizilombo toyambitsa matenda? Mankhwalawa amaperekedwa kwa akuluakulu mkati. Mlingo wake umadalira mtundu ndi kuopsa kwa matendawa.

• Herpes zoster 1000 mg katatu patsiku kwa sabata.
• Herpes simplex ndi 500 mg kawiri pa tsiku. Ngati abwereranso, maphunzirowo amatha masiku 3-5, ndipo pa nthawi yoyamba - mpaka masiku khumi.
• Labial herpes - 2 g 2 pa tsiku. Mlingo wachiwiri uyenera kutengedwa pambuyo pa maola 12.
• Kupewa matenda omwe amabwera chifukwa cha kachilombo ka herpes simplex, mwa anthu omwe ali ndi kachilombo koyambitsa matenda - 500 mg kamodzi patsiku, ndipo nthawi zambiri amatha kubwerera - 250 mg kawiri patsiku, akuluakulu omwe ali ndi immunodeficiency - 500 mg kawiri pa tsiku. Kutalika kwa mankhwala ndi miyezi 5-12.
• Kupewa matenda a cytomegalovirus achinyamata ali ndi zaka zoposa khumi ndi ziwiri ndipo akulu ndi ma gramu awiri kanayi pa tsiku. Kutalika kwa mankhwala ndi miyezi itatu.

Momwe mungapewere matenda a wathanzi wabwino kutenga mankhwala "Valvir" (1500) kuchokera ku herpes? Akatswiri amanena kuti anthu omwe ali ndi chitetezo chamthupi, komanso mobwerezabwereza, amalembedwa mankhwala okwanira 500 mg pachaka pa chaka. Ndizochita zachiwerewere zosayenera, muyenera kuyamba kumwa mankhwala masiku atatu.

Mlingowo uyenera kuchepetsedwa kwa odwala omwe ali ndi vuto lopweteka kwambiri.

Milandu ya pulogalamuyi imadutsa

Kodi zizindikiro ndizoti Valvir sakusamalidwa bwino? Malingaliro a madotolo amasonyeza zizindikiro zotsatirazi zowonjezereka: chisokonezo, chisokonezo, kusanza, chitukuko cha kuchepa kwa chiberekero, kumutu kwa mutu, kuwonjezeka kwa ndondomeko ya serum creatinine, kukhumudwa, kukhumudwa, kukhumudwa, kuphwanyidwa.

Ozunzidwa ayenera kuyang'anitsitsa kuchipatala kuti azindikire zizindikiro za poizoni.

Hemodialysis ikhoza kuthetsa acyclovir kuchotsa magazi.

Zovuta zochitika

Kodi ndi zotsatira zotani zomwe zingachitike ndi kugwiritsa ntchito mankhwala "Valvir" (500 mg). Malingaliro a odwala makamaka nthawi zambiri amalankhula za zotsatira zovuta monga kusokonezeka ndi kumutu. Komanso, mankhwalawa amachititsa kuti thupi likhale lopweteka kwambiri ngati mawonekedwe a thrombotic thrombocytopenic purpura, kupwetekedwa kwa nsomba, hemolytic-uremic syndrome ndi matenda a ubongo.

Kuwonjezera pa zomwe zili pamwambapa, akatswiri amalankhulanso za zotsatirazi zotsatirazi:

• Kusokonezeka m'mimba;
• Leukopenia, thrombocytopenia;
• Anaphylaxis;
• Kusokonezeka, chizungulire, kusokonezeka, kupsinjika maganizo, kusokonezeka, zizindikiro za maganizo, kupotoza maganizo, kuchepa mtima, kuchepa kwa maganizo, kuchepa;
• Dyspnoea;
• Rashes, photosensitivity, kuyabwa;
• Angioedema, ming'oma;
• Kusokonezeka mu ntchito ya impso;
• Masomphenya osalimba;
• Neutropenia, leukoplastic vasculitis, kuchepa kwa magazi m'thupi, thrombocytopenic thrombotic purpura;
• Erythema multiforme;
• Hypercreatininaemia, kuchepa kwa hemoglobin;
• Matenda opatsirana, kutentha thupi, tachycardia, arthralgia, kutopa, nasopharyngitis, kutaya thupi, kutaya nkhope, kutentha thupi, kuwonjezeka kwa magazi, nthendayi.

Malangizo apadera okhudza Valvir (momwe mungatengere: musanadye chakudya kapena mutadya)?

Madokotala amanena kuti mankhwalawa samadalira chakudya. Choncho, ikhoza kutengedwa kapena popanda chakudya. Chinthu chachikulu ndikusunga nthawi yofanana pakati pa mlingo wa tsiku ndi tsiku.

Tiyeneranso kukumbukira kuti okalamba sali oyenera kusintha mlingo, kupatula ngati pali zovuta zazikulu mu ntchito ya impso.

Chidziwitso cha ntchito yachipatala kwa ana aang'ono palibe. Choncho, kulimbikitsidwa kuti musapereke mankhwala otero kwa ana ochepera zaka 12-14.

Ndemanga za mankhwala

Herpes ndi kachilombo kamene kakuvutitsa anthu ambiri padziko lonse lapansi. Choncho, mankhwalawa "Valvir" amafunika kwambiri pamsika wamagetsi. Malinga ndi ndemanga za odwala, mankhwalawa amathandiza kuthetsa msampha wam'mimba, komanso kusintha kwabwino kwa wodwalayo.

"Valvir" imagwiritsidwa ntchito osati kokha pofuna kuchiza kachilombo, komanso pofuna kuteteza. Anthu ambiri amadziwa kuti akamamwa mankhwalawa, kuchepa kwa herpes kumachepa.

Ndizosatheka kunena ndipo kuti, mogwirizana ndi malamulo onse oyenera kumwa mankhwala, sichimayambitsa mavuto. Komabe, ziyenera kukumbukira kuti pamodzi ndi ndemanga zabwino, mankhwalawa ali ndi vuto. Ambiri a iwo ali ofanana ndi mtengo wapatali wa mankhwala. Pakalipano, mapiritsi khumi (500 mg) a Valvir angagulidwe kwa ruble 600-680.