Mankhwala 'Warfarin. Malangizo ntchito

Mankhwala "Warfarin" malangizo ntchito amatanthauza gulu la anticoagulants wa mozungulira kanthu. Mankhwala akhoza ziletsa kaphatikizidwe zinthu clotting (vitamini K amadalira) komanso mapuloteni C ndi S mu chiwindi. Mulingo woyenera anticoagulant zotsatira anati pa tsiku lachitatu kapena chachisanu pambuyo mwambo wa mankhwala ndi kutsazikana atapita masiku atatu ndi zisanu mlingo lomaliza. The mankhwala ndi alembedwe piritsi.

Ndi bwino pamene mukumwa mankhwala "Warfarin" zakudya kumaphatikizapo kukhalabe pafupifupi yofanana vitamini K pa chakudya

umboni

mankhwala akusonyeza kuti kupewa ndi kuchiza wa thrombosis ndi thromboembolism. Ndi zizindikiro mankhwala "Warfarin" malangizo Buku la khuzana thromboembolism ndi thrombosis pachimake venous, embolism m'mapapo mwanga, zisadzachitikenso wa infarction m'mnyewa wamtima, thrombosis postoperative. lokonzekera Kwalamulidwa kwa ndikukhazikitsa ndi thromboembolic kuchotsa kapena thrombosis opaleshoni (monga njira zina) kuti matenda fibrillation (magetsi cardioversion), relapsing (kachiwiri) mtsempha thrombosis, embolism mu mtsempha wamagazi ndi m'mapapo mwanga. Amatanthauza "Warfarin" malangizo Buku akuonetsa mu yopanga mtima ndi mavavu mtima (amene ali ololedwa ndi ntchito ophatikizana asidi acetylsalicylic). Komanso, mankhwala Kwalamulidwa kwa thrombosis oziziritsa, inatsekeratu ndi zotumphukira mitsempha, komanso kupewa yachiwiri ya thrombosis kapena embolism pa m'kuphethira wa matenda kapena pambuyo infarction.

Contraindications buku mankhwala "Warfarin" malangizo m'gulu tsankho munthu, aimpso kapena matenda kwa chiwindi kwambiri, pachimake kukha mwazi oopsa (lolemera authunthu), exacerbation zilonda m'mimba kapena duodenum, hemorrhagic diathesis, kupanda S ndi C mapuloteni, uchidakwa, kukha mwazi kwa muubongo, aimpso ntchito insufficiency, pachimake DIC, thrombocytopenia. Kusankha mankhwala pa mimba.

Ambiri zochitika chowawa pa akuluakulu a mankhwala "Warfarin" magazi. Nthawi zina, pali necrosis wa khungu, kuchuluka chiwindi michere, kutsekula m'mimba, chikanga, tsitsi imfa, vasculitis.

mlingo

mankhwala akusonyeza kuti makonzedwe m'kamwa. Analimbikitsa ntchito limodzi, mu nthawi yomweyo. Koyamba mlingo - awiri ndi theka mamiligalamu asanu pa tsiku.

Anasintha dosing kamwedwe "Warfarin" (INR kapena nthawi prothrombin pamene izi n'komwe) anatsimikiza payekha. Mu kawiri anayi kuchokera ku gwero ayenera chinawonjezeka nthawi prothrombin. Pankhaniyi INR (mayiko dekhetsa chiŵerengero) afike (malingana ndi kudwala Mwina wa magazi, thrombosis ngozi) 2.2-4.4.

Kwa odwala achikulire kapena chikhalidwe wofooka Kwalamulidwa Mlingo m'munsi mwa mankhwala "Warfarin".

Tisanapite kukakambirana ntchito (mu nkhani ya kutengera za ku chitukuko cha mavuto thromboembolic) mankhwala akuyamba masiku awiri kapena atatu pamaso alowererepo pa.

Mu thrombosis mankhwala pachimake ikuchitika osakaniza ndi mankhwala "Heparin" mpaka nthawi pamene anticoagulant zotsatira si bwino akuwonetseredwa (zambiri osati kwa tsiku lachitatu ndi wachisanu).

Kutalika kwa mankhwala zimadalira alili.

Pamaso pa chiyambi cha mankhwala n'kofunika kudziwa ndi INR index (malinga ndi nthawi prothrombin, anapatsidwa tilinazo koyefishienti thromboplastin).

Malinga ndi odwala ambiri, mankhwala "Warfarin" si zogwira mtima, komanso yabwino, popeza ayenera kumwedwa kamodzi kokha patsiku. Komanso amatanthauza bwino analekerera, mavuto n'zochepa. Komabe, musanagwiritse ntchito mankhwala, muyenera kukaonana ndi katswiri, ndi kuwerenga malangizo mosamala.