Mankhwalawa "Ranitidine": zizindikiro zogwiritsidwa ntchito, zolemba ndi katundu

Matenda a m'mimba - vuto lalikulu lomwe limakhudza anthu mosasamala za msinkhu komanso kugonana. Mwachitsanzo, nthawi zambiri ana amayamba kuchepetsa matendawa, ndipo nthawi zina amakhala ndi ana aang'ono. Mwamwayi, mankhwala amasiku ano amapereka ndalama zambiri kuti azitsatira njira yotupa ya kapangidwe ka zakudya. Ndipo mmodzi wa iwo ndi mankhwala "Ranitidine". Zizindikiro zogwiritsiridwa ntchito mankhwalawa ndizowona kwambiri. Ndiye ndi chiyani chomwe chimaphatikizidwa mu chiyambi chake ndi chida chothandiza bwanji?

Mankhwalawa "Ranitidine": mawonekedwe ndi mawonekedwe a kumasulidwa

Chinthu chachikulu cha mankhwalawa ndi ranitidine hypochloride. Mwachibadwa, ndi ufa wonyezimira (nthawi zina ndi chikasu chachikasu) ndi fungo la sulfure ndi kulawa kowawa. Izi zimakhala ndi zida zotsutsana ndi histamine H2 receptors.

Mankhwalawa amapezeka ngati mapiritsi, kapena ngati njira yothetsera vutoli. Pali zotchedwa "effervescent" mapiritsi okonzekera njira yothetsera madzi.

Mapiritsi ndi ozungulira, biconvex, okhala ndi chivundikiro cha lalanje pamwamba. Monga zothandizira zothandizira: sodium lauryl sulfate, microcrystalline cellulose, colloidal silicon dioxide, starch chimanga, magnesium stearate, titani dioxide, hypromellose, polyethylene glycol 6000, ethylcellulose ndi chikasu.

Pakalipano, makampani opanga mankhwala amapereka mapiritsi okhala ndi 150 mg kapena 300 mg yogwiritsira ntchito mankhwala. Njira zowonongeka zimapezeka m'makandulo ampoules a 2 ml.

Pharmacological katundu wa mankhwala "Ranitidine"

Monga tanenera kale, chinthu chachikulu chogwiritsira ntchito mankhwalawa chimatsekedwa ndi H2-histamine abodza. Mankhwalawa amakhudza makamaka ntchito ya maselo a parietal mu chapastro mucosa. Pansi pa mphamvu yake, kumasulidwa kwa hydrochloric acid kukuletsedwa, zomwe zimapangitsa kuchepa kwa voliyumu ya chapamimba madzi, komanso kuchepa kwa acidity. Mwa njira, ndicho chifukwa mankhwalawa "Ranitidine" otha kupweteketsa mtima ndi othandiza kwambiri.

Tiyenera kudziŵa kuti olemba mbiri ya histamine receptors amachepetsa mavitamini a m'mimba (pepsin) mu madzi a m'mimba. Kuponderezedwa kumapangitsa kuti munthu azidwala zilonda zam'mimba, zomwe zimawathandiza kuchira.

Kuonjezera apo, zigawo zikuluzikulu za mankhwalawa zimakhudza gastroduodenal zone, kuwonjezera ntchito ya njira zotetezera zowonongeka, kuonjezera chitetezo cha chitetezo cha mucous secretions. Mankhwalawa amathamangitsanso njira yobwezeretsanso.

Pamodzi ndi izi, mankhwala alibe zotsatira zoopsa pa thupi. Makamaka, sizimakhudza ma intoni ya calcium m'magazi, sizimasokoneza dongosolo la endocrine, silikukhudza njira za spermatogenesis. Zotsatira za maphunzirowa zasonyezeranso kuti mankhwalawa alibe chifuwa chachikulu komanso samayambitsa kusintha kwa thupi. Komano, mankhwala othandizira amalowa m'mbali mwachitsulo ndi mkaka wa m'mawere.

Pambuyo kumwa mankhwala, imatengedwa mwamsanga ndi khoma la kapangidwe ka zakudya. Kutsekemera kwakukulu mu magazi kumachitika patatha maola 2-3. Nthaŵi zambiri, zotsatira zimakhala pafupifupi maola 12. Pakugwiritsidwa ntchito kwa kagayidwe ka shuga kamasintha pang'ono m'chiwindi. Anachotsedwa kwathunthu mu thupi la impso pasanapite nthawi.

Mankhwalawa "Ranitidine": zizindikiro zogwiritsidwa ntchito

Mankhwalawa amagwiritsidwa ntchito kwambiri monga antiulcer. Komabe, pali zolakwa zambiri zomwe madokotala amapereka mankhwala otchedwa "ranitidine". Zizindikiro zogwiritsira ntchito ndi izi:

• Kutentha kwa mtima;
• Peptic chilonda cha m'mimba ndi matumbo aang'ono;
• Kwa lero, mankhwalawa "Ranitidine" ndi gastritis amagwiritsidwa ntchito kwambiri;
• Chosonyeza kuti chimagwiritsidwanso ntchito ndi isophagititis, yomwe imayambitsidwa kuponyedwa m'mimba ya m'mimba mwake kapena ikuphatikizidwa ndi kuphwanya kwa mucosal minofu;
• Mankhwalawa amathandiza anthu odwala matendawa ngati akuwoneka ndi ululu waukulu wa epigastric wogwirizana ndi kudya;
• Mankhwalawa amagwiritsidwa ntchito pochiza matenda ena oopsa;
• Monga mankhwala othandizira ogwiritsidwa ntchito mu aspiration pneumonitis ndi nyamakazi ya nyamakazi;
• Chithandizochi ndi mbali ya mankhwala opatsirana m'magazi kumtunda kwa dongosolo;
• Monga mankhwala ochizira amauza odwala omwe anachitidwa opaleshoni pa ziwalo za m'mimba.

Dziwani kuti matenda oopsa siwo okhawo omwe amafunika mankhwala ndi mankhwala "Ranitidine". Zizindikiro zogwiritsiridwa ntchito zikuphatikizapo ndikuletsa kuwonjezereka kwa matenda aakulu a gastritis ndi zilonda zam'mimba.

Momwe mungatengere mankhwala molondola?

Inde, musanayambe kumwa mankhwalawa, mukufunikira kufunsa dokotala. Mlingo uliwonse umatsimikiziridwa payekha, malinga ndi msinkhu komanso momwe thupili likuyendera, mawonekedwe a matenda, cholinga cha kuvomereza (mankhwala kapena kupewa):

• Odwala achikulire amawonetsedwa mapiritsi ndi mlingo wa mankhwala yogwira ntchito 150 mg kawiri tsiku lililonse. Nthaŵi zina, madokotala amati amalandira mapiritsi awiri kamodzi asanagone.
• Pofuna kuteteza magazi, wodwalayo amachitidwa operesi (kapena intravenously) pa 0.05-0.1 g ndi periodicity ya maola 6-8 (ngati kuli koyenera, mlingowo ukhoza kuwonjezeka kufika 0.9 g).
• Achinyamata, monga lamulo, atenge 150 mg kawiri pa tsiku.
• Pochiza matenda otupa, mlingo woyenera ndi 150 mg ya mankhwala yogwira ntchito katatu patsiku.

Kawirikawiri, nthawi ya chithandizo ndi masabata anayi kapena asanu ndi atatu. Ngati ndi funso loletsa, odwala ena amalimbikitsidwa kumwa mankhwalawa kwa miyezi ingapo, ndipo nthawi zina kwa chaka chonse, koma nthawi zonse akuyang'aniridwa ndi dokotala komanso kafukufuku wokhazikika.

Contraindications kugwiritsa ntchito mankhwala "Ranitidine"

Monga mankhwala ena alionse, mankhwalawa sangagwiritsidwe ntchito ndi wodwala aliyense. Makamaka, saloledwa kugwiritsidwa ntchito pochizira amayi pa nthawi ya mimba ndi lactation, monga zinthu zomwe zimagwira ntchito mosavuta zimafika mu mkaka ndikudutsa chigwacho. Kusiyanitsa ndi kugwiritsira ntchito mankhwala osokoneza bongo. "Ranitidine" siigwiritsidwe ntchito pochiza ana osakwana zaka 14.

Kuonjezera apo, wothandizirawa amagwiritsidwa ntchito mosamala pochiza odwala omwe amapezeka ndi vuto lopanda mphamvu kapena lachiberekero, komanso odwala porphyria ndi chiwindi cha chiwindi.

Ndi zotsatira zotani zomwe zingatheke panthawi ya mankhwala?

Mwamwayi, zigawo zikuluzikulu za mankhwalawa zimakhudza pafupifupi zamoyo zonse. Choncho, kwa odwala ena, mankhwalawa akhoza kugwiridwa ndi zotsatira zina zoipa:

• Kawirikawiri ankawona kupweteka mutu, kugona, kuwonjezeka kwa nkhawa, kutopa, chizungulire, masomphenya olakwika. Pa milandu yowopsa kwambiri, mankhwalawa angabweretse chisokonezo, chitukuko cha mikhalidwe yovuta, zomwe zimachitika potsutsana.
• Kusokonezeka kwa mitsempha ya mtima, makamaka kuchepetsa kuthamanga kwa magazi, kutsekemera kapena hemolytic anemia, arrhythmia, tachycardia, thrombocytopenia, kawirikawiri - mafupa a hypoplasia.
• Zomwe zimayambitsa matendawa zimayendera limodzi ndi maonekedwe a khungu ndi kuyabwa, malungo, kutupa, erythrema. Kawirikawiri, mankhwalawa amachititsa anaphylactic kusokonezeka.
• Mwinamwake kuwoneka kwa mseru ndi kusanza, kupweteka m'mimba. Kawirikawiri mankhwala amachititsa kuti chitukuko chiwonjezeke komanso mitundu ina ya chiwindi.

Ngati zotsatira zina zimachitika, samani kumwa mankhwala ndikufotokozera dokotala zizindikiro.

Zambiri zokhudza mankhwala

Musanayambe kumwa mankhwalawa, monga lamulo, kufufuza mozama kumachitika, popeza ndikofunika kwambiri kuti muone ngati palibe ziwalo zoopsa m'mimba ndi m'mimba. Chowonadi ndi chakuti mankhwalawa akhoza kusokoneza zizindikiro zazikulu za khansa.

Kuchiza kwa nthawi yaitali kwa odwala omwe ali ndi mphamvu yotetezera chitetezo cha m'thupi komanso kutopa kwa thupi kungachititse kuti mabakiteriya awonongeke m'mimba.

Kudya kwa "Ranitidine" kuyenera kuchepetsedwa pang'onopang'ono, kuchepa kwa mlingo tsiku ndi tsiku. Kuchetsa kwa mankhwala mofulumira kungayambitse kupweteka kwa zilonda zam'mimba.

Kodi mankhwala "Ranitidine" amagwirizana bwanji ndi mankhwala ena?

Kawirikawiri, mankhwalawa amawagwiritsa ntchito mankhwalawa ndi antacids, omwe amachepetsa acidity mmimba. Zikatero, kupuma pakati pa kugwiritsa ntchito mankhwalawa ayenera kukhala osachepera maola 1-2.

Mankhwalawa "Ranitidine" amachititsa kuti ketoconazole ikhale yovuta, komanso imachepetsa mphamvu ya metabolism m'chiwindi cha diazepam, metronidazole, lidocaine ndi mankhwala ena. Mwa njira, kusuta kwambiri kumachepetsa zotsatira za kumwa mankhwalawa.

Mankhwalawa "Ranitidine": ndemanga za odwala

Maphunziro a odwala omwe amagwiritsira ntchito mankhwalawa amakhala abwino. Anthu amazindikira zotsatira zenizeni za mankhwalawa. Mankhwalawa "Ranitidine" amathandiza kuthetsa kupweteka kwa mtima, kumachepetsa kwambiri zizindikiro za gastritis. Ubwino wa mankhwalawa ukhoza kugwiritsidwa ntchito ndipo ndi wotsika mtengo. Zotsatira zoipa zimachitika kawirikawiri.