Matenda Parkinson

matenda Parkinson (Aka "Parkinson", izo "idiopathic parkinsonism", izo "parkinsonism chachikulu," Aka "PD", izo "hypokinetic Parkinsonism" ndipo - "kugwedeza manjenje") - ndi wonongeka wa chapakati mantha osachiritsika chikhalidwe cha kachitidwe. Njinga zizindikiro zomwe limodzi matenda Parkinson kugwirizana ndi maselo substantia nigra kufa kutali (m'chigawo chapakati cha ubongo) yotulutsa dopamine. Kalanga, sayansi masiku ano si koma yankho la funso la chifukwa maselo amenewa mwadzidzidzi anayamba kufa. Pa chiyambi cha njira odziwika matenda zizindikiro ziwonekera anthu amene mwanjira ina kapena imzake, zokhudza kayendedwe ka.

Zizindikiro za matenda Parkinson lapangidwa ineyo ndi kunthunthumira, chinthu chimodzimodzi ndi kusakwiya kuyenda ndi, monga Motero, ndi gulu sitepe ya vuto. Kenako, ndi chitukuko cha matenda, pangakhale vuto la chidziwitso ndi khalidwe. Mu masiteji ina ya matenda odwala kawirikawiri zachulukazi ndi chizindikiro cha maganizo. Zizindikiro zina za matenda Parkinson monga mavuto ndi tulo, maganizo ndi sensorics. matenda Parkinson ndi ambiri okalamba, ndipo matenda ali nthawi zambiri anati pambuyo pa zaka 50.

Nthawi zambiri madokotala pamene kupanga matenda "matenda Parkinson", ndi anawonjezera kuti izo koma ndi mawu akuti "idiopathic", ndiye amene yeniyeni, mwamsanga chifukwa si kukhazikitsa zotheka. Komabe, mankhwala odziwika milandu angapo atypical parkinsonism imene kukhala matenda kunathandiza mwachindunji ndi chikhalidwe cha zinthu chibadwa.

Pakali pano, asayansi apeza zinthu zingapo monga kulepheretsa chitukuko cha matenda Parkinson, ndipo amathandiza kuti chitukuko. Mwachitsanzo, mosakayikira anapeza kuti chiopsezo kukhala ndi matenda osuta ... pansipa. Koma nthawi zambiri anthu amakhudzana ndi mankhwala ena, m'malo mwake, ndi mwayi apamwamba kudwala matendawa Parkinson.

Pathologically matenda amakhala ndi kudzikundikira mapuloteni mu zimakhala za thupi, lotchedwa alpha-synuclein. Chotero kudzikundikira lotchedwa "Lewy matupi", iwo wapezeka mkati manyuroni wa substantia nigra. Kuwonjezera pamenepa, pali osakwanira kukula kwa ntchito matenda ndi dopamine Parkinson opangidwa ndi ubongo.

matupi Lewy ali ngati chizindikiro cha parkinsonism idiopathic. Number maselo ali kuvutika ubongo matenda Parkinson, ndi index munthu, koma izo zikhoza kugwirizana ndi mwamphamvu ndi zochita matendawa payekha. Matenda a matenda Parkinson nthawi potengera zizindikiro za matenda. mayesero osiyanasiyana neuroimaging ntchito kutsimikiza matenda.

njira zatsopano, yomwe ikuchitika chithandizo cha matenda Parkinson, ndi chokwanira kuthana bwino ndi mawonetseredwe oyambirira a matenda amene amakhudza gululi. Komabe, ndi chitukuko cha matenda ndi wotsatira selo imfa kubala dopamine, njira zimenezi akukhala kuchepa ogwira. Komanso vuto ikutuluka matenda wodwalayo, lotchedwa "dyskinesia" imene kumaonekera kayendedwe musanaganizire jerky. Komabe, malinga ndi zotsatira asilikali yakuthandizani, chikhalidwe ichi Mungathe kuchepetsa kuvutitsana mwa zakudya ndi mitundu ina ya Zochita konzanso. Komanso, mpumulo zizindikiro mwina ntchito opaleshoni kwambiri kukondoweza ubongo. Njirazi ndi umboni pamene ntchito mankhwala ena ndi mankhwala sititenga. Komabe, kafukufuku umalimbana kupeza njira zatsopano ndi odalirika amachitira matenda Parkinson, akupitiriza kuti zizichitidwa.