"Teopeka" (300 mg): malangizo ntchito, zizindikiro, wopanga

Anthu ndi mphumu, amadziwa nthawi kufunika kukathandiza bronchospasm. Nthawi zina kanthu zoona zimenezi zitakuchitikirani akhoza kupulumutsa miyoyo. A mbali yofunika kwambiri kupeza anthu ku mavuto m'mapapo kusewera bronchodilators.

Kufotokozera lokonzekera

"Teopeka" (300 mg), malangizo ntchito chomwe chili mu pepala ili ndi miyala woyera ploskotsilindricheskoy mawonekedwe zozungulira, amene ankanyamula mu atanyamula mizere. Waukulu yogwira pophika mankhwala ndi theophylline. ndende zake piritsi limodzi tsiku lokonzekera la mtundu uwu ndi 300 mg.

Kodi mankhwalawa?

Mwa zochita zake pharmacological wa theophylline, amene ndilochokera ku purine, ali zimakhudzanso inhibiting pa phosphodiesterase lapansi. The yogwira pophika midadada mankhwala enieni purine zolandilira, kumapangitsa msasa kudzikundikira mu omwetsera minofu, Sachita luso minofu yosalala minofu kutenga, kuchepetsa kuchuluka kwa ufulu kashiamu ayoni, omwe amasamukira kudzera nembanemba selo.

Amalembedwa kutchulidwa vasodilating zotsatira phwando "teopeka" kukonzekera (300 mg). Malangizo ntchito limafotokoza katundu monga chimachita pa Mitsempha zotumphukira. Theophylline kumawonjezera magazi kudzera dongosolo aimpso, kumalimbikitsa zosangalatsa za yosalala ziwiya bronchial minofu ndi magazi. Komanso, ntchito ya chigawo yogwira amakhala ngati diuretic wofatsa. Theophylline kumathandiza kumasulidwa kwa zinthu mkati ndi kunja, ochititsa munthu amene matupi awo sagwirizana komanso kumawonjezera mtendere wa nembanemba mlongoti selo. Ngati wodwala hypokalemia yogwira mankhwala wagundika mpweya wabwino.

Theophylline amathandiza matenda kugwira ntchito kupuma, mphamvu pakati lolingana mu ubongo, chifukwa mu bwino magazi mpweya machulukitsidwe, izo amachepetsa ndende ya mpweya. Mankhwala "teopeka" kumapangitsa munthu zakulera, moti kudula. Komanso kumawonjezera mtengo wa chizindikiro cha ntchito mucociliary chilolezo wagundika kupuma ndi intercostal minofu.

Theophylline kumabweretsa yachibadwa magazi mikrotsirkullyatsiyu kumachepetsa thrombus mapangidwe, chinthu limaleka yeniyeni ndipo kumatha loitanirana maselo kupatsidwa zinthu za m'mwazi. mankhwala bwino otaya khalidwe magazi, kumaonjezera kukana kuti deforming erythrocytes zinthu.

"Teopeka" (300 mg), potero kuchepetsa kuthamanga chokwanira mwa kufalitsa m'mapapo mwanga, komanso amachepetsa kukana mu dongosolo m'mapapo mwanga mtima. Chifukwa, kamvekedwe ka integuments khungu, impso ndi ubongo amachepetsa. Chifukwa cha kulandira theophylline amalembedwa kukondoweza akulowera inatsekeratu magazi, kulalikira mwakhama mtima, kuchuluka kwa m'mnyewa wamtima maselo zidzasintha ayenera mpweya, kufulumizitsa zimachitika, mphamvu ya contractions mtima achuluka.

Pharmacokinetics ndi pharmacodynamics mankhwala

Pambuyo wodwala anatenga mapiritsi ndi theophylline, mankhwala kwathunthu odzipereka kwa mundawo m'mimba. Chakudya chakumwa ali zimakhudzanso mlingo wa mayamwidwe wa mankhwala, koma mlingo wa mayamwidwe ndi chilolezo amakhalabe sichinasinthe. Popeza plasma mapuloteni chimamanga 40% ya mankhwala yogwira. Theophylline kagayidwe akupezeka chiwindi ndi cytochrome P450.

Excretion wa metabolites opangidwa mu thupi lithe kudzera impso, koma 10% ya mankhwala likuchotsedwa mu maonekedwe ake apachiyambi. Pali zinthu zina zomwe ndi zotsatira kwambiri pa kagayidwe wa theophylline. Kusuta fodya, kumwa mankhwala ena, makhalidwe zakudya, comorbidities, zaka, kusintha kwa nzeru thunthu yogwira m'thupi la munthu. Kuchepetsa chilolezo cha theophylline zimawonedwa mu m'mapapo edema, chiwindi matenda, COPD, ndi matenda a mtima.

Amene angathe kulandira chida ichi?

Pali zinthu zina zimene ndi "teopeka" (300 mg). Malangizo ntchito limafotokoza matenda otsatirawa:

• matenda obstructive mu mawonekedwe aakulu;
• matenda obanika kutulo;
• ndiko kumayambitsa;
• mphumu;
• oopsa m'mapapo mwanga;
• mtima m'mapapo mwanga.

Komanso, mankhwala "teopeka" ndemanga yothandiza yomwe ingagwiritsidwe molumikizana ndi mankhwala ena mankhwala a aimpso edema chikhalidwe. Odwala onani Mwachangu mkulu wa chida ndi kuvomereza ake zochizira matenda a dongosolo kupuma.

contraindications

Komabe, mankhwala akhoza kugwiritsidwa ntchito si aliyense, chifukwa cha kukhalapo kwa angapo machenjezo kwa ndalama. "Teopeka" contraindications ali motere:

• hemorrhagic sitiroko mtundu;
• khunyu;
• magazi kuchokera thirakiti m'mimba m'mbiri;
• chilonda lomenyera ziwalo m'mimba;
• tachycardia mkulu severities;
• oopsa kapena hypotension;
• hypersensitivity;
• gastritis, limodzi ndi asidi wambiri;
• Ana kwa zaka 12.

Pamaso pa imodzi ya syndromes awa kapena zikhalidwe za theophylline mankhwala ayenera kusiya

zotsatira zoyipazi

Pali ndithu gulu lalikulu la mbali-zotsatira sanaphe "teopeka" kukonzekera (300 mg). Malangizo ntchito magawo awo pa mawonetseredwe zokhudza zonse:

• matenda ya ubongo: mutu, chizungulire, tulo zipolowe, m'chikaiko chowakaikitsa, kuchuluka nkhawa ndi irritability, kenaka utentha mamba;
• kukanika mtima ndi magazi zotengera: tachycardia, arrhythmia, hypotension, kuchuluka pafupipafupi kuukira angina, angina wabodza;
• kuphwanya m'mimba yachibadwa kugwira ntchito: nseru, gastralgia, kusanza, kutentha, Reflux, zilonda exacerbation, kutsekula m'mimba, utachepa kudya;
• maonekedwe a thupi lawo siligwirizana: ziwengo, malungo, oyabwa;
• mwa zochitika zina chilango chochokera kutenga mankhwala amene anati: tachypnea, albuminuria, kuchuluka diuresis, kupweteka kwa sternum, hematuria, ankatenthetsa, kuchuluka thukuta, gipoglekemiya.

Childs, malangizo a mlingo kuti muchepetse mavuto yafupika kapena ikutha palimodzi.

Kodi kutenga mankhwala?

Amatanthauza ku matenda, monga "teopeka", oikidwa okha ndi dokotala kupezeka ndi mlingo awo amusankha anthu paokhapaokha. Wapakati tsiku Nome liri 400 mg theophylline. Ngati wodwala amanyamula mankhwala bwino, ndiye atatha masiku 2-3 pa mlingo woyamba wa mankhwala, buku chinawonjezeka ndi 25% ndi zina mwa mobisa dokotala.

Atalandira kudzera ku chifuwa "teopeka" mu mlingo tsiku la zosakwana 900 mg ndi theophylline zili m'manja Sikuti mu magazi wodwalayo. Ngati mungafufuze chiwonetsero cha kuledzera, pakufunika kukhazikitsa ulamuliro pa mlingo wa ndende ya waukulu yogwira pophika m'magazi. Best ankaona zizindikiro micrograms 10-20 pa ml. Ngati theophylline zili magazi wodwalayo ndi apamwamba kuposa masiku onse, anaona chitukuko cha kukwiya. Pankhaniyi m'pofunika kuchepetsa mlingo wa mankhwala, ndipo zotsatira achire kuzilala.

Kodi pali ambiri osokoneza?

Bronchodilators monga "teopeka" angayambitse matenda aakulu kwa thupi likhoza cha mankhwala osokoneza bongo. Pamene bwino chikufanana mlingo tsiku la kutanthauza kulandira zizindikiro zotsatirazi angakhalepo:

• utachepa kudya;
• tulo;
• m'mimba;
• yamitsempha yamagazi arrhythmias mawonekedwe;
• tachycardia;
• magazi a dongosolo m'mimba;
• tachypnea;
• kugwedeza;
• nkhawa;
• ankatenthetsa wa khungu ;
• kuchuluka excitability;
• mantha monsemo;
• akusanza magazi.

Kukhoza kukhala poyizoni kwambiri, amene kumaonekera zizindikiro zotsatirazi:

• yatsoka a khunyu khunyu;
• hypokalemia;
• aimpso kulephera, myoglobinuria;
• hypotension;
• chisokonezo;
• hyperglycemia;
• kagayidwe kachakudya acidosis.

Kodi kuchita mu nkhani iyi?

Ngati pali umboni zizindikiro kapena kukayikitsa muyenera kupanga lavage chapamimba, kupereka chelators mtima, mankhwala ofewetsa tuvi, mankhwala, komanso bungwe diuresis plasmasorption, hemodialysis ndi hemosorption. Ngati wodwala khunyu, ndiye izo tikulimbikitsidwa kuti atchule mankhwala mpweya ndi mtsempha "ntchito diazepam" amene angatithandize bwino kudzagwira kudwala. Pankhani ya nseru kutchulidwa ndi kusanza Uike mtsempha "Ondansetron" mankhwala ndi "Metaklopromida".

Kodi mankhwala sangathe pamodzi "teopeka"?

Bronchodilators monga "teopeka sayenera kutenga pamodzi ndi macrolide-maantibayotiki" Allopurinol "," cimetidine "," Lincomycin "," isoprenaline ", komanso kulera m'kamwa chifukwa mankhwala awa amathandiza kuchepetsa chilolezo cha theophylline.

Iwo ali osavomerezeka kuphatikiza madyedwe a beta-blockers, makamaka sanali kusankha, ndi mankhwala "teopeka", umene ungapezeke bronchial constriction ndi kuchepa bronchodilator zotsatira za theophylline.

Ngati "teopeka" ntchito limodzi ndi "Furosemide" tiyi kapena khofi ndi zinthu zina kuti yotithandiza beta-2 adrenergic zolandilira, ntchito ya chigawo zake zikuluzikulu ali kwambiri kuchuluka. Ngati amaphatikizidwa ndi theophylline "Aminoglutitemidom", ulusi woyamba umayamba mwachangu excreted ku thupi ndi madontho ake dzuwa.

"Acyclovir" angathe kuonjezera ambiri waukulu yogwira pophika "teopeka" ndi kuonjezera mavuto obwera chifukwa cha phwando ake. zochitika zofanana ndi ananena pamene co-kutumikiridwa ndi mankhwala theophylline "Dialteazem", "Felodipine" "Verapamil", "Nefedipin". mankhwala amenewa sangasinthe bronchodilator zotsatira Komabe, kuleza mtima nacho zizindikiro za zochita chokhwima kapena ambiri osokoneza.

Thunthu "Disulfiram" angathe kuwonjezeka theophylline magazi zizindikiro yovuta woopsawo poizoni chotupa. "Propranolol", mosiyana, amachepetsa "teopeka" chilolezo wa chinthu yogwira. Ambiri theophylline ndi chinawonjezeka ndi somestnom phwando ake ndi "enoxacin" ndi fluoroquinolones. Pamene mankhwala theophylline amachepetsa Mwachangu salt lifiyamu.

Ngati ophatikizana mankhwala ndi "pentobarbital", "Carbamazepine", "Isoniazid", "rifamycins", "sulfinpyrazone" kuchuluka chilolezo "teopeka" ndi kusagwira ntchito zake. Pamene concomitantly ndi theophylline "phenytoin" pali ndicho chopinga wa chigawo mwakhama magazi wodwalayo.

Ntchito kwambiri, kunyalanyaza iwo ndi zinadzala ndi matenda. Choncho, asanadye "teopeka", werengani malangizo mosamala. Ndipo ngati inu akulandira thandizo aliyense wa mankhwala pamwamba, dokotala anu.

Kodi kugula mankhwala ndi mmene mankhwala ndi ofunika?

Polingalira contraindications zazikulu ndi zotsatira zake zoyipa za mankhwala, "teopeka" anamasulidwa mu pharmacies yekha ndi mankhwala.

Mankhwala "teopeka" mtengo ndi ambiri Russia ndi rubles 160, naperekanso mu pharmacies ndi opanga zosiyanasiyana. mtundu - mankhwala kwa "Borschagovsky CPP SPC" makampani Chiyukireniya mankhwala. mtengo wake ndi 155 rubles. kupanga Russian "teopeka" mankhwala, 300 mg ikuchitika pa mabizinezi a JSC "mankhwala malonda" ndi "Valens". mankhwala ndalama 290 rubles ndi 190 rubles motero.

Ambiri, mankhwala "teopeka", mtengo zili zovomerezeka, ankaona mankhwala angakwanitse chifukwa anthu ambiri a m'dzikoli wathu. Poyerekeza ndi Anzawo European chida ichi ndi mtengo kwambiri. Russian yopanga "teopeka" mankhwala anamveketsa angagulidwe.

Akuchenjeza pamene mukumwa mankhwala

Pamene kulandira "teopeka" mankhwala, ndemanga zimene ziri zabwino, ayenera kulabadira mfundo zotsatirazi. Ngati wodwalayo inatsekeratu kapena mtima insufficiency, atherosclerosis, cardiomyopathy, m'mimba chilonda, chiwindi matenda, khansa prostate, oesophageal Reflux, mimba, hypothyroidism kapena kuchuluka propensity kwa khunyu, ndi theophylline mankhwala ayenera kumwedwa mosamala.

Ana osaposera zaka 12 ndi odwala achikulire "teopeka" yoikidwiratu kawirikawiri.

Mwina a mitundu thumbo mankhwala, koma iwo ayenera kugwiritsidwa ntchito mosamala kwambiri mu pathologies ya rectum ndi m'mimba matenda. Odwala bongo ndi kusuta mfundo kutsitsa zotsatira za mankhwala "teopeka".

Akuti inadmissible olowa chithandizo theophylline ndi xanthine ofanana nawo. Ngati wodwala okalamba kuzimwera matenda concomitant, tizilombo, matenda a chiwindi, ndi zotengera mtima ndi magazi, dokotala m'pofunika kukonza mlingo wa mankhwala.

Ndingatani kutenga mankhwala kwa amayi apakati?

Mayi woyembekezera ndi medicament akusonyeza pamaso pa zikuonetsa aakulu kuyambira theophylline amatha umalowa mu nsengwa. Ngati phwando "teopeka" akusonyeza mayi woyamwitsa, ndi mkaka wa m'mawere ayenera anasiya.

Bukuli ndi chidule cha malangizo wathunthu, amene anaphatikiza mankhwala "teopeka". Kuyenera kuwerenga mozama musanachite ntchito. Ngati pali chinachake inu sakumvetsa kapena mukukayika, kufunsa dokotala.