Urea m'magazi. Kulera ndi kutsitsa zili

Urea ndi apanga m'kati neutralization la ammonia mu chiwindi. Iwo aumbike mwa zochita za kwa amino asidi deamination. Urea anafotokoza kuti mankhwala kulemera otsika maselo. Amatha ulere kudutsa nembanemba ndi khungu la erythrocytes ndi ziwalo parenchymal. urea ku kusefera magazi kumachitika mu glomeruli lapansi. Koma nthawi yomweyo reabsorption ake kwambiri (chabe) ikuchitika tubules lapansi.

Urea magazi limafotokoza monga kaphatikizidwe wa mlingo glomerular kusefera ndi perfusion aimpso.

pawiri uyu ali otsika kawopsedwe, koma kawopsedwe wa zotumphukira guanidine adzalandira ayoni potaziyamu kudziunjikira ndi izo. Urea ndi chinthu osmotically, chotero pamene umaonekera kudzikundikira edema mu zimakhala ziwalo parenchymatous, myocardium, dongosolo chapakati mantha, subcutaneous minofu.

magazi urea (ndende zake plasma) amaona chizindikiro cha aimpso chipangizo glomerular ntchito. Komabe, kudzitamandira zolondola imagwiridwa zomwe zili creatinine.

Kuwonjezeka urea mapangidwe anamuona pa ntchito yambiri mapuloteni limati catabolic, komanso mayamwidwe mapuloteni ndi kwa amino zidulo pambuyo magazi muzituluka. Kuwonjezeka ndende wake anamuona pa madzi m'thupi chifukwa kuchuluka chabe reabsorption mu tubules impso.

Yafupika magazi urea (plasma) pansi kupanga kwa chiwindi ntchito matenda, komanso ndi osakwanira mapuloteni wambiri. Okhutira pawiri mu seramu achuluke chifukwa phwando mankhwala munthu. Mankhwalawa monga phenylbutazone, anabolic mankhwala, dopegit, zowonjezera chitsulo, aldomet, mankhwala nephrotoxic.

Kuchepetsa wa urea mu magazi zingasonyeze chiwindi matenda (a chiwindi, mu kuphatikizapo tizilombo ndi matenda enaake, zotupa). Ichi ndi chifukwa chakuti thupi ili pali mapangidwe pawiri zofunika. Pamene kuphwanya amapezeka ndi kupanga chiwindi matenda urea. Pankhaniyi, zizindikiro za matenda nthawi zonse zodziwika bwino. Zizindikiro zazikulu ayenera kutengedwa ngati kufooka, kusakhala ndi chilakolako, kutopa, matenda a chikasu ndiyo owawa belching, kusapeza mu hypochondrium bwino.

Mu matenda a dongosolo m'mimba pamodzi ndi malabsorption la amino zidulo amapanga mapuloteni mu nthawi postoperative zokhudzana zikunena matenda matumbo, aakulu kapamba, parasitic matenda ananenanso yafupika urea m'magazi. Chithandizo cha ichi kayenela kuthetsa matenda chimapangitsa. Monga ulamuliro, pambuyo ndiyotani pakuchotsa matenda ndi mayesero dekhetsa.

Tikumbukenso kuti zili pawiri mu mkodzo anatsimikiza ndi ndende zake magazi. Komanso amaganizira kuchuluka kwa kusefera mu impso.

Normal magazi urea ndi 2,8-8,3 mmol / l. Childs, pamene ndondomeko ya nthaŵi kagayidwe mapuloteni, nkhani zake kawirikawiri anati zoposa 6 mmol / l. Mwina pali zakudya otsika ku mapuloteni, ndende pawiri yafupika 2 mmol / lita.

Kuchuluka urea m'magazi (zambiri ndende ndi angapo yachibadwa chapamwamba zizindikiro), zambiri limodzi ndi kuledzera kwambiri, wotchedwa uremia. Iwo anati chikhalidwe ofanana pa maziko a matenda otsatirawa:

- aimpso kulephera pachimake mawonekedwe;

- pyelonephritis, glomerulonephritis;

- anuria (pakalibe syndrome mkodzo, munthu defecate);

- shuga;

- zotupa kapena concrements mu mkodzo kapena ureter;

- amayaka;

- peritonitis;

- mantha;

- phenol poizoni, Mercury salt, chloroform;

- gastro-m'mimba magazi.