"Zyprexa": malangizo ntchito. "Zyprexa": ndemanga, analogs ndi contraindications

Mantha dongosolo la munthu ndi malo lamulo la chamoyo wonse. Ngati muli ndi mavuto mukhoza kusunga zolakwika mu chitukuko, mwakuthupi ndiponso ndi m'maganizo mwanu. Panopa, pali chiwerengero chachikulu cha mankhwala akhoza ntchito zodabwitsa ndi kuthana ndi matenda ambiri. Mmodzi wa iwo - "Zyprexa". Nkhaniyi tidzakambirana kuti izi Buku mankhwala malangizo. "Zyprexa" - mankhwala zambiri analamula kuti kuvutika mu wamanjenje dongosolo.

Pharmacological katundu wa mankhwala

mankhwala ili gulu la neuroleptics ndi zotsatira pa sipekitiramu yotakata kachitidwe ambiri cholandilira. Maphunziro ambiri yomwe anapeza kuti olanzapine, ndi yogwira pophika mankhwala, ali chidani kwa serotonin, dopamine, ndi maselo cholinergic.

Anapeza kuti olanzapine amachepetsa excitability wa mesolimbic manyuroni dopaminergic ndi kwenikweni pa njira striatal ubongo komwe kumachititsa lamulo ntchito galimoto.

The yogwira pophika mankhwala timapitiriza odana ndi nkhawa kwenikweni pa nthawi ya kuyesedwa anxiolytic.

Medicine "Zyprexa" pawiri:

• Mu maonekedwe a mapiritsi, filimu TACHIMATA.
• Lyophilizate kwa yokonza njira jekeseni.

Waukulu yogwira pophika yokonza limapangidwa olanzapine. zigawo wothandiza mapiritsi ndi:

• Crospovidone.
• mankhwala enaake a stearate.
• Lactose monohydrate.
• Mapadi.
• Giproloza.

The zikuchokera miyala filimu ❖ kuyanika mwayera colorant, chakudya buluu inki, phula carnauba ndi hypromellose.

The zikuchokera lyophilisate ndi njira yothetsera jekeseni zikuphatikizapo kusiya waukulu mankhwala yogwira, lactose monohydrate acid tartaric.

Mu mawonekedwe zimene kuika mankhwala kuchiza wodwala, dokotala amafunika kusankha okha.

Zikuonetsa ntchito mankhwala

Mankhwala "Zyprexa" ali zizindikiro zochuluka ntchito, nthawi zambiri izo Kwalamulidwa zinthu zotsatirazi:

• Akuchita misala mu mawonekedwe pachimake.
• Mitsempha matenda limodzi ndi zinyengo, kuyerekezera zinthu m'maganizo, ndinaganiza matenda.
• Kulankhula chidani ndi kukayikirana kwa matenda mantha.
• Maganizo kapena chikhalidwe achire.
• Zizindikiro Affective kumene ndi maziko a akuchita misala.
• Monga nthumwi prophylactic kwa musabise akuchita misala.
• Maganizo.

Sikuti kuti asankhe yekha mankhwala popanda kufunsira ndi katswiri, zimenezi ndi zinadzala ndi mavuto aakulu.

Chiwembu mankhwala

Kodi izi Buku malangizo? "Zyprexa" akapatsidwa pa chiyambi cha mankhwala a akuchita misala mu mlingo osachepera. Poyamba, zidzakhala zokwanira kutenga 10 mg wa mankhwala kamodzi pa tsiku. Mphamvu ya mankhwalawa kudya chakudya alibe chochita.

Mlingo achire mankhwala akhoza zimasiyana 5 mpaka 20 mg, koma udzakhazikitsidwe munthu mmodzi wodwala aliyense polingalira uliri. Atafufuza onse, ngati wodwalayo amalola mlingo mankhwala akhoza zochuluka, koma moyang'aniridwa ndi achipatala.

Pamaso pa chizunzo kukonda "Zyprexa" piritsi kutumikiridwa mu kuchuluka kwa 15 mg tsiku lililonse. Pa chithandizocho m'pofunika kuyan'ana mkhalidwe wa mtima ndi mlingo kusintha koyenera.

Ngati wodwala akudwala kwa chiwindi kapena aimpso insufficiency, iye chinafotokoza mankhwala "Zyprexa" 5 mg, ngati boma si zachilendo ndipo amatanthauza bwino analekerera, mlingo akhoza ziwonjezeke pang'onopang'ono.

mankhwala kawirikawiri kutumikiridwa odwala ndi jekeseni. Musanasankhe jakisoni, muyenera bwino kupasuka kwa lyophilisate. Kuchita izi, nkhani za mbale uli kusungunuka mu 2 ml ya madzi a jekeseni. Yankho okonzeka iyenera kukhala yomveka bwino ndiponso ndi mtundu wachikasu.

Kodi kutenga? "Zyprexa", monga tanenera kale, amagwira ntchito katswiri. Choncho, kamwedwe chithandizo, ngati chithandizocho ikuchitika kunyumba, ayenera kukambirana dokotala.

Pokonzekera njira jekeseni tiyenera kukumbukira:

• "Zyprexa" akhoza zidzasungunuka mu madzi wosabala yekha.
• Izo sizingakhoze osokonezeka mu syringe yemweyo mankhwala ndi "ntchito diazepam".
• Pawiri "Zyprexa" ndi "Haloperidol" kumayambitsa chifooke zochita za mankhwala oyamba.

Ngati dotolo n'kukulemberani mankhwala "Zyprexa", mlingo kudzadalira matenda. Mwachitsanzo, mu akuchita misala mlingo koyamba ndi 10 mg tsiku lililonse. Mankhwala ayenera kuperekedwa intramuscularly yekha. Ngati chofunika ndi alili, wachiwiri kubaya mankhwala akhoza kupanga, koma osati maola kale kuposa awiri pambuyo jekeseni choyamba.

Achikulire odwala ndi kukhalapo kwa matenda ena aakulu mankhwala kutumikiridwa mu mlingo wa 2.5-5 mg.

Podziwa kuti kumayambiriro "Zyprexa" kungakhale kugwa magazi pa jekeseni ndi bwino kukhala mu malo kunama, makamaka ngati pambuyo kusinza jekeseni ndi chizungulire. M'pofunika kunama, bola ngati dokotala ndikatha kumfunsafunsa sadzakhala kukonza kupanda kuchepetsa magazi ndi bradycardia.

Tiyeneranso kukumbukira kuti chiyembekezo chakuti a "Zyprexa" ayenera ikuchitika pang'onopang'ono, monga mmene mankhwala syndrome achire. Nthawi zonse muyenera kukambirana ndi dokotala.

Yaitali mankhwala "Zyprexa" Patapita nthawi jekeseni m'malo miyala mu mlingo wa 5 kuti 20 mg wa pa tsiku. dokotala chofunika mwatsatanetsatane mmene mankhwala "Zyprexa" yaitali chiyenera kulandiridwa. Kuti amachitira njira nanga chithandizo chiwembu, ife kuwunikira, koma tiyenera kukumbukira za mmene osafunika.

Zotsatira zoyipa za mankhwala

Pafupifupi mankhwala zochizira dongosolo matenda mantha zokhudzana m'gululo, limene tikulimbikitsidwa kuti kutenga popanda kufunsa dokotala. Izi si zosiyana kwa "Zyprexa" chifukwa mankhwala ali ndi mndandanda m'malo yaikulu mavuto:

• Mantha dongosolo mungachite kupweteka chizungulire, kufooka ambiri ndi tulo, amnesia ndi phobias zosiyanasiyana. Kenaka utentha mamba ndi minofu stiffness komanso zitheka. Nthawi zambiri pali tinnitus, ugonthi, kupweteka maso, kukoma chisokonezo.
• Pa mbali ya dongosolo mtima kungakhale tachycardia, kusiya magazi, kusintha ECG, cyanosis. Nkhani tingasonyeze neutropenia, eosinophilia, leukocytosis, thrombocytopenia. Zikavuta, nkotheka mtima kumangidwa.
• Pali chiopsezo rhinitis, pharyngitis, laryngitis, chifuwa kuchuluka. Kodi kuvutika mphumu, matenda obanika kutulo ndi chiopsezo.
• Khunyu kuonjezera kudya kapena bulimia, ludzu, dryness mu M'mimbamo m'kamwa.
• Kunyansidwa ndi kusanza.
• Exacerbation a gastritis ndi gastroenteritis.
• Kuphwanya mpando ndi flatulence.
• matenda kagayidwe kachakudya angasonyeze kulemera kusintha, kukula kwa matenda a shuga, matenda a shuga chikomokere.
• Mkodzo incontinence, cystitis, fibrosis uterine, amenorrhea ndi chitukuko cha matenda thirakiti mkodzo nawonso osafunika mawonetseredwe ingestion.
• Malangizo Ntchito ( "Zyprexa", pamene ife tikuwona, mankhwala ndi zomwe zingachititse zosiyanasiyana zotsatira zapathengo mbali) limatichenjeza kuti chitukuko zotheka nyamakazi, bursitis, omangana m'minofu ng'ombe ndi ululu mafupa.
• Khungu angamvere maonekedwe a dryness kwambiri, dermatitis, chilonda formations.
• urticaria amapezeka pafupipafupi.
• Zizindikiro zina kudziŵika malungo, kuzizira, boma chimfine.

Kuchokera pamwamba pa zonse tinganene kuti "Zyprexa" mavuto ndi lalikulu zokwanira, kotero kumwa mankhwala okha malangizo dokotala.

Zizindikiro cha mankhwala osokoneza bongo

Ngati wodwala safuna kutsatira malangizo dokotala kwa mlingo wa mankhwala, pali chiopsezo cha mankhwala osokoneza bongo, amene anaonetsa zizindikiro zotsatirazi:

• Tachycardia.
• Kugwiritsa irritability ndi ndewu.
• Kulankhula matenda.
• Mkhutu kutsitsimuka.
• Zopweteka.
• Neuroleptic syndrome.
• Chopinga wa ntchito ya kupuma.
• Kudumpha magazi.
• Arrhythmia.
• Zikavuta, mtima kumangidwa ndi kupuma.

Poyamba chizindikiro cha mankhwala osokoneza bongo ndi kofunika kusamba kunja m'mimba, kutenga makala. chithandizo Symptomatic ikuchitika malinga ndi mawonetseredwe matenda, ndi zonse kuwunika ntchito ya ziwalo zofunika kwambiri.

Contraindications ntchito mankhwala

Kupewa mawonetseredwe osafunika atakhala "Zyprexa" m'pofunika mosamala mndandanda wa contraindications. Kuti zinthu monga:

1. Kuchuluka kudziwa mankhwala.
2. Depression ya ubongo.
3. Chikomokere.
4. Age zaka 18.
5. Mosamala ayenera mankhwala mankhwala "Zyprexa" matenda otsatirawa ndi zikhalidwe:

• Impso ndi kulephera chiwindi.
• Khungu.
• Khunyu.
• Prostatic hyperplasia.
• Myelosuppression.
• Phenylketonuria.
• Manjenje ileus.
• Mimba.
• Pa yoyamwitsa.

Ngati wodwalayo osachepera amodzi mwa matenda otsatirawa kapena zinthu zimene muyenera ndithudi kudziŵitsa dokotala.

Kutenga mankhwala pa mimba ndi yoyamwitsa

Ngati mkazi amathera mankhwala ndi "Zyprexa" ndipo anakhala ndi pakati, muyenera kudziwitsa dokotala. Mankhwala m'nthawi ya gestation mwana atengeko kokha pamene phindu kwa mayi n'kosangalatsa lingathe chiopsezo kwambiri kwa mwana wosabadwa.

"Zyprexa" - antipsychotic, okhoza kudutsa mu mkaka wa m'mawere, choncho panthawi mankhwala sayenera kupitiriza mwana wanu, ndi bwino kusinthana kwa kudya yokumba.

ayamikira yeniyeni mkati mankhwala

Azamisala zambiri kusiya kusankha pa mankhwala "Zyprexa", mtengo umene, mwatsoka, si mkulu. Choncho, paketi imodzi ya mapilisi (. 5 mg, 28 zidutswa) ndalama 2500 rubles, ndi botolo limodzi jekeseni -. 239 pakani.

Pafupifupi mankhwala onse a m'gulu limeneli amatha hule chitukuko cha matenda neuroleptic, ndi "Zyprexa" yotero. Pa mankhwala ayenera kusamala, ngati pali kusokonekera zimachitika kapena tachycardia, arrhythmia, kapena thukuta, kuchuluka kutentha thupi, muyenera auzeni adokotala.

Chipatala kuwonekera kwa matenda neuroleptic zilonda amafuna kuti mankhwala mwamsanga zimafika.

Maphunziro matenda yomwe anapeza kuti nthawi yaitali mankhwala "Zyprexa" sikawirikawiri limodzi ndi dyskinesia, yomwe inafunika alowererepo zachipatala. Koma musaiwale kuti pali chiopsezo cha chitukuko ina ya vuto limeneli.

Ngati pali zizindikiro zilizonse za psoriasis, m'pofunika kusintha mlingo motsogozedwa lawo Ndikulichepetsa.

Pamaso pa matenda "chiwindi kulephera" mankhwala ayenera kumwedwa mosamala kwambiri, makamaka ndi kuchuluka kwa Ast ndi alt. Ngati kanjedza kufika pamlingo yovuta, m'pofunika kuchepetsa mlingo wa "Zyprexa."

Mankhwala ayenera kumwedwa mosamala, ngati mbiri wodwalayo anali ndi khunyu khunyu kapena zonse poyera kuti zinthu zimene kuchepetsa kulanda pakhomo.

Ngati mayesero mtima anawonetsa chepetse chiwerengero cha maselo oyera kapena neutrophils, njira "Zyprexa" ayenera idzachitika moyang'aniridwa ndi achipatala ndi nthawi kuwunika magawo magazi. Choncho zikusonyeza malangizo ntchito. "Zyprexa" imafunanso kugwilizana ndi kusamalidwa pa chithandizo ngati:

• Pali zizindikiro za chinyengo kapena kulakwila poizoni m'mafupa.
• Pamaso pa matenda concomitant zomwe ziletsa mafupa ntchito.
• Ngati mbiri ya wodwalayo radiotherapy kapena mankhwala amphamvu.
• Pamaso pa hypereosinophilia.

Pophunzira experimental Therapy "Zyprexa" sikawirikawiri limodzi ndi zotsatira anticholinergic chowawa, koma zinachitikira ntchito mankhwala odwala ndi matenda concomitant ndi ang'ono, chithandizo, ngati n'koyenera, zizichitidwa mochenjera ndipo kokha moyang'aniridwa ndi achipatala.

ileus ndi chatsekedwa ngodya khungu komanso ndi maziko zochizira mosamala za mankhwala "Zyprexa". Ntchito ya mankhwala pa chapakati mantha dongosolo amafuna kugwilizana ndi kusamala, ngati n'koyenera osakaniza ndi mankhwala ena amagawanika.

Mankhwala si pamodzi ndi mowa, choncho panthawi mankhwala sayenera kumwa zakumwa zoledzeretsa.

Poganizira kuti pamene mankhwalawa "Zyprexa" zikhoza kusinza, ndiye nthawi ili ndi bwino kupewa kuyendetsa galimoto, komanso ntchito za ntchito yofunika ndende kwambiri.

Kodi kuphatikiza "Zyprexa" ndi mankhwala ena

Kagayidwe wa waukulu yogwira pophika mankhwala akhoza zimasintha mchikakamizo cha zoletsa kapena inducers wa cytochrome P450, omwe khama ntchito yawo ndi CYP1A2. Chilolezo "Zyprexa" ndi zayamba kuchuluka odwala amene ali ndi chizolowezi monga kusuta, komanso kutenga mankhwala "Carbamazepine".

maphunziro chipatala asonyeza kuti ngati pali mlingo umodzi wa "Zyprexa" ndi mankhwala "warfarin", "theophylline", "ntchito diazepam", "Imipramine", kuchepa atsopano mu kagayidwe unkachitika.

Dongosolo munthawi yomweyo mankhwala ndi mowa ndi zinadzala ndi kumatheka sedative katundu wa mankhwala, tingayambe kufooka ndende.

Co-makonzedwe ndi "Zyprexa" "fluoxetine" kumawonjezera ndende pazipita yogwira mankhwala olanzapine. Koma odwala onse, chinthu zimenezi mawu osiyana, kotero mlingo kusintha pa mosamalitsa payekha.

Ngati "Zyprexa" chiphunzitso kutumikiridwa intramuscularly molumikizana ndi benzodiazepines, Ndi bwino kuchita bwinobwino mmene matenda a wodwalayo poyerekezera chopinga a dongosolo kupuma ndi minofu mtima. Chipatala maphunziro a kuphatikiza mankhwala sizinakhale, ngati nkotheka ayenera kuzipewa.

Mawu oyamba a mankhwala ndi zinadzala ndi chitukuko cha bradycardia kapena magazi m'munsi, ndiponso chithandizo chake ngati zizichitidwa mosamala kwambiri odwala amene ali ndi mavuto mu dongosolo mtima, ndiponso syncope anali anati dontho lakuthwa mu chipsyinjo.

Iwo ayenera kukumbukira kuti utsogoleli wa adamulowetsa makala kapena kukonzekera mankhwala ochotsa asidi kwambiri amachepetsa suction ndondomeko "Zyprexa" kapepala kakuti matumbo, zomwe zingathe kusokoneza Mwachangu chithandizo.

kusamalitsa pa mankhwala "Zyprexa"

Ngati pali zinthu zomwe zimathandiza pang'onopang'ono kagayidwe wa olanzapine, muyenera kuchepetsa mlingo. Kuti zinthu zimenezi ndi izi:

• Female.
• Pamaso pa makhalidwe oipa monga kusuta fodya.
• Ukalamba.

Ngakhale kuti nthawi kutumikiridwa "Zyprexa" mankhwala zimenezi zimafuna chisamaliro chapadera kwa odwala amene ali kapena anali amafuna kudzipha.

Pa mankhwala ayenera kuwunika ntchito ya transaminases kwa chiwindi, makamaka odwala ndi mkhutu ntchito chiwindi.

Odwala, amene akatswiri ntchito amagwirizana ndi galimoto kapena ntchito zimene amafunika chisamaliro chapadera ndi ndende, mankhwala Kwalamulidwa mosamala. Ngati n'kotheka, m'malo mankhwala wina.

Ngati pali zizindikiro za neuroleptic zilonda syndrome mu mawonekedwe a malungo, tachycardia, kuphwanya kwa thupi, muyenera kusiya kumwa mankhwala.

Popeza mankhwala galimoto m'chikaiko chowakaikitsa "Zyprexa" zikhoza m'chikaiko chowakaikitsa, chilakolako zonse kusuntha, m'pofunika kuchepetsa mlingo pang'ono ndipo perekani wothandizila antiparkinsonian.

analogues mankhwala

"Zyprexa" analogues ali magulu awiri:

1. Mau ofanana, mwachitsanzo, kukhala ndi yogwira mankhwala. gulu izi zikuphatikiza mankhwala zotsatirazi: "Zalasta," "Olanzapine", "Parnasan", "Olaneks", "Normiton".
2. Gulu lachiwiri zikuphatikizapo mankhwala amene ali pa thupi la munthu wofanana zotsatira pharmacological, monga "Azaleptin", "Viktoel", "Ketilept", "Kutipin", "Lakvel", "Nantarid", "Safris" ndi ena.

Ngati dokotala wanu wadzikakamiza monga mankhwala mankhwala "Zyprexa", analogues sayenera kuthamangira kukatenga, kotero inu mukhoza kukwaniritsa kufunika kwenikweni achire. Only dokotala zingatithandize kuthetsa nkhani imeneyi. Chilakolako m'malo mankhwala kufanizira ndi kulungamitsidwa, chifukwa mankhwala "Zyprexa" mtengo si mkulu, koma mogwira zake zoyenera ndalama.

Reviews kukonzekera

Pakali pano, pafupifupi aliyense Wopirira musanapite mankhwala kwa mankhwala zotchulidwa dokotala, khalani okonzeka kuwafunsa za maganizo a anthu amene ali kale kulandira mankhwala. "Zyprexa" mayankho zambiri ali positive. Odwala amene alandire mankhwala ndi mankhwala chake Mwachangu mfundo mkulu. Ngakhale pambuyo Inde waukulu wa mankhwala, odwala ambiri kuti yokonza Mlingo wa mankhwala salola matenda kuti abwerere ndiponso musabise pafupifupi kulibeko. Good kumenyana mankhwala maganizo, kumene patapita Inde mankhwala si kufufuza wakukhala, ndipo pali wofuna kukhala ndi moyo.

Iwo ayenera kukumbukira kuti ngakhale kuti "Zyprexa" ali ndemanga zabwino, odwala ambiri zindikirani chiwonetsero cha mavuto. Makamaka zambiri kumachitika chifukwa cha mankhwala izi onenepa, kusokoneza kagayidwe, ena amati m'chikaiko chowakaikitsa ndi chikhumbo zonse kuchita chinachake.

Nthawi zambiri, odwala komanso amadandaula mtengo kwambiri za mankhwala, amene salola kuti atenge magulu ena a anthu.

Panopa, mmodzi wa matenda mu nkhokwe ya madokotala pali ambiri mankhwala, koma ndikatha kumfunsafunsa zonse, adokotala akhoza kusankha mmodzi wa iwo. Choncho si kofunika paokha anaika mankhwala ndi mankhwala omwewo angakhale ndi zotsatira zosiyana pa odwala. Izi zidalira pa makhalidwe a chamoyo ndi, mmene ambiri ndi zochita matenda. Izi makamaka nkhawa kukonzekera zochizira matenda ya ubongo. Dzisamalire ndi kukhala wathanzi!