"Cefoperazone + Sulbactam": malangizo ntchito, analogs, ndemanga

Panopa, pali chiwerengero chachikulu cha matenda opatsirana, umene uli pafupi zosatheka kusamalira popanda mankhwala. Ndi zofunika kuti mankhwala ankatha kuti zoyipa pa ambiri tizilombo. Zina mwa "Cefoperazone + Sulbactam." More yodziwa zikuonetsa ntchito mankhwala.

mawonekedwe Ndinamasulidwa zikuchokera

Mankhwala chikupezeka monga ufa njira. Iwo kutumikiridwa m'nsinga kapena intramuscularly. Thunthu yogwira ali ndi kuchuluka kwa ceftazidime 1 g

Mankhwala "Cefoperazone + Sulbactam" (malonda dzina - "Sulperazon" kapena "Sulperatsef") ndipo ali gulu la mankhwala antibacterial.

The kanthu pharmacological mankhwala

mankhwala ili njira pamodzi. Medicament "Cefoperazone" ndi njira yotakata-sipekitiramu mankhwala. Iye anali kungasokoneze aerobic ndi anaerobic zamoyo zambiri bakiteriya.

Kukonzekera "Sulbactam" ndi woletsa sizingasinthe wa beta-lactamases. Iwo chindiletsa chiwonongeko cha penicillin ndi cephalosporins, kuyambira pawiri zinaonetsedwa pa chionetserocho synergy nawo.

The medicament "Cefoperazone + Sulbactam" ochitachita zotsatira zake likuwonongekera maselo ndi inhibiting peptidoglycan, lomwe ndi mbali yofunika ya mabakiteriya makoma.

Mankhwala excreted ku thupi za 8 maola wa mkodzo. Hafu ya moyo wa maola awiri. Ngati wodwala kulandira mankhwala, akuvutika chiwindi matenda, pamene ukuwonjezeka mankhwala excretion.

Code JECFA "Cefoperazone + Sulbactam» - 24.42.11.228. Mankhwala opangidwa ku India.

Zikuonetsa ntchito mankhwala

mankhwala akusonyeza pamaso pa matenda omwe amayamba ndi tizilombo tcheru ndi mankhwala yogwira. Njirazi ndi monga:

• Pharyngitis.
• Zilonda zapakhosi.
• Matenda.
• kutukusira kwa mapapo.
• M'mapapo abscess.
• Matenda a dongosolo mkodzo, monga cystitis, chinzonono, prostatitis, vulvovaginal.
• matenda ENT.
• matenda khungu zachilengedwe opatsirana: furunculosis, pyoderma, abscesses ndi ena.

• Matenda mwa olowa.
• Sepsis.
• Meninjaitisi.

mankhwala nazonso anatengedwa ngati njira muyeso bakiteriya zosokonezeka pambuyo opaleshoni.

Kukonzekera "Cefoperazone ndi Sulbactam Dzhodas" amasonyezanso mu peritonitis, cholecystitis, cholangitis ndi matenda ena kwapakati pa-m'mimba. Cholinga cha anapeza mankhwala ndi nthawi ya mankhwala ndi chithandizo regimens ayenera chinkhoswe yekha ndi dokotala.

Amatanthauza "Cefoperazone ndi Sulbactam Spencer" waperekedwanso kwa cholinga kupewa.

Amene si amalangiza kumwa mankhwala

Ngakhale zosiyanasiyana za lonse zochita, chida ichi chikhonza sichizalandiridwa akamaziwononga:

• Pamaso pa hypersensitivity kwa mankhwala.
• Pa yoyamwitsa "Cefoperazone + Sulbactam" amagwiritsidwanso contraindicated.
• Aimpso kwa chiwindi kulephera amafuna kugwiritsa ntchito mosamala kwambiri.
• Pamaso pa matenda a m'matumbo m'mbiri wodwalayo.

Asanayambe chithandizo ndi mankhwala muyenera kuwonetsetsa kukambirana ndi dokotala wanu pamaso pa contraindications.

Zotsatira osafunika pa mankhwala

Mankhwala "Cefoperazone + Sulbactam" malonda dzina lake ndi "Sulperazon" pa mankhwala zingachititse chiwonetsero cha zotsatira zotsatirazi mbali:

• Ku dongosolo mkodzo angathe hematuria.
• dongosolo mtima angayankhe kuchepa magazi kapena vasculitis.

• Analysis magazi pa mankhwala amagwiritsa kuchepa kwa magazi, yafupika hematocrit, thrombocytopenia, eosinophilia, leukopenia ndi kuvutika ena.
• Yafupika albumin misinkhu.
• Bilirubin encephalopathy ana akhanda akhoza kukhala ndi matenda a chikasu ndiyo.
• Pa mbali ya thirakiti m'mimba mwina dyspepsia, kusanza, ndipo pseudomembranous matenda a m'matumbo.
• Pa khungu angaoneke zotupa maculopapular totupa, ndi kuyabwa kwambiri.
• Laboratory maphunziro asonyeza chinawonjezeka chiwerengero cha mayesero ntchito chiwindi.
• Jekeseni malo soreness mankhwala alipo, pamene kutumikiridwa m'nsinga kudzera catheter wa - phlebitis.
• Wochepetsetsa kuona mutu, malungo, ndi zina zosiyanasiyana anaphylactic wa chamoyo.

Pa zosayembekezereka chamtundu uliwonse osafunika ayenera kukambirana nkhaniyi ndi dokotala. Inu mukhoza kuganizira mlingo wa mankhwala "Cefoperazone ndi sulbactam" kapena kuletsa izo palimodzi.

Kodi tingayembekezere ndi ambiri osokoneza mankhwala

Ngati inu kutenga mankhwala kuyang'aniridwa okhwima dokotala, ndi ambiri osokoneza muyenera musadandaule, koma chifukwa chololera mankhwala zambiri zotheka. Ngati thupi analandira mankhwala kwambiri kuposa chofunika, pangakhale matenda a ubongo, kuphatikizapo khunyu.

Chithandizo mu nkhani iyi ikuchitika malinga ndi zizindikiro. Zothandiza kwambiri hemodialysis.

Mlingo ndi Chithandizo kamwedwe

Ngati yoikidwiratu mankhwala "Cefoperazone + Sulbactam" malangizo Buku akuonetsa kuti jekeseni ya mankhwala m'nsinga kapena intramuscularly. Kwa odwala wamkulu mlingo tsiku ndi zambiri kuchokera 2 gm 4 wa pophika yogwira. ndalamazo ayenera kugawidwa mu magawo awiri.

Ngati wodwala ali aakulu matenda mlingo akhoza ziwonjezeke kwa magalamu 8, zomwe tiyeneranso kugawidwa Mlingo awiri patsiku. Ngati palibe ofanana matenda aakulu ambiri odwala, ndi mlingo tsiku kuchuluka kwa magalamu 12-16 kulekerera popanda akuoneka mbali.

Kutalika kwa mankhwala anatsimikiza ndi dokotala. Mwachitsanzo, pamene wopepuka gonococcal urethritis kutumikiridwa kamodzi 500 mg wa mankhwala.

Ndi cholinga kupewa mavuto pambuyo kukonzekera opaleshoni chikuyendetsedwera kuti wodwala 1-2 ga m'nsinga ola limodzi pamaso ntchito. mankhwalawa uyenera kubwerezedwa pambuyo maola 12. Ngati opaleshoni imagwiridwa ndi chiopsezo cha mavuto monga HIV mosavuta, utsogoleli prophylactic amapitirizabe kwa masiku 3 pambuyo msonkhano.

Odwala amene chisokonezo impso ndi, mankhwala "Cefoperazone + Sulbactam" akapatsidwa mu mlingo wa osapitirira 4 magalamu patsiku. Ngati pali mavuto ndi chiwindi, mlingo yafupika ngakhale kawiri.

Popeza mankhwala angathe kuperekedwa kudzera m'mitsempha intramuscularly, pali zina mwa ntchito zake.

Pamene kutumikiridwa m'nsinga monga zosungunulira ufa angagwiritsidwe ntchito:

• 5% dextrose njira.
• Saline.
• madzi wosabala jekeseni.

Pamene kutumikiridwa m'nsinga, ufa mu botolo limodzi ayenera zidzasungunuka mu 10 ml ya zosungunulira abwino. M'pofunika kudikira kuvunda wathunthu ndi mankhwala kutumikiridwa pang'onopang'ono mphindi 3-5.

Ngati adzagwa mankhwala "Cefoperazone + Sulbactam" malangizo Buku akuonetsa 1 galamu ya pophika yogwira. Kuti, nkhani za mbale wina zidzasungunuka mu 5 ml ya madzi a jekeseni, ndipo onjezerani ku njira kulowetsedwa, kubweretsa ndende kuti 20-100 mg / mL. Popeza kuchuluka kwa njira kuti adzagwa, mpheto nthawi zingakhale za Mphindi 10 mpaka 30.

Dongosolo mu mnofu kupasuka ufa akhoza kugwiritsidwa ntchito kapena madzi a jekeseni kapena sodium kolorayidi. Chiŵerengero amagwiritsidwa ntchito motere: 0,5 ga mankhwala kutenga 2 ml ya zosungunulira.

Popeza pamene kutumikiridwa mankhwala ambiri zimachitika ululu pa malo jekeseni, izo tikulimbikitsidwa kuti pokonza njira mankhwala anawonjezera "lidocaine wa 2%", koma pa chikhalidwe kuti wodwalayo si matupi awo sagwirizana ndi mankhwala.

Matenda alionse opatsirana jakisoni kupereka zotsatira zabwino ndi mofulumira, kotero jakisoni ndi kutumikiridwa mu "Cefoperazone + Sulbactam." Mapiritsi alinso pang'onopang'ono kwambiri.

Ntchito mankhwala ana

Ana zambiri amadwala matenda amene palibe mankhwala sitingapeze kuchita. Mlingo tsiku la yogwira mankhwala cefoperazone pakati ayenera kukhala ku mg ndi 50 200 pa kilogalamu thupi la mwanayo. Kutumikiridwa mankhwala ayenera ofanana mbali ndi kulekanitsa mu magawo awiri.

Desirably, tsiku mlingo si upambana 12 F. Ngati mankhwala jekeseni bolus, unit mlingo sayenera upambana 50 mg / kg.

ana akhanda akhoza kutumikiridwa 50-200 mg wa mankhwala pa kulemera kilogalamu thupi, nagawira mu magawo awiri mwa maola 12. Kuchokera pa zaka zambiri angagwiritsire ntchito chida pa matenda a ana, tinganene kuti Mlingo mpaka 300 mg pa kilogalamu ya kulemera kwa thupi pa tsiku bwino analekerera ndi ana, ngakhale pamaso pa meninjaitisi bakiteriya.

Ntchito ya mankhwala pa mimba

Medicine ndi yogwira pophika ceftazidime oletsa akazi pamalo kokha pamene limati ngati kumene ubwino kwa mayi woyembekezera kangapo wamkulu kuposa chiopsezo kuthekera kwa mwana wosabadwa. Ngati mukufuna kugwiritsa ntchito mankhwala pa kuyamwitsa, adokotala amalangiza pa nthawi ino kusamutsa mwana kudya yokumba.

Mogwirizana ndi mankhwala ena

Mankhwala "Cefoperazone" pa katundu pharmacological sali pamodzi aminoglycoside ndi. Ngati pali kufunika mu mankhwala a magulu awiriwa mankhwala, iwo kutumikiridwa mu mawonekedwe a makonzedwe likukulira kudzera awiri catheter osiyana.

Co-ka mankhwala ndi thrombolytic, antiplatelet ndi NSAIDs kumaonjezera ngozi ya magazi.

Kwa odwala ndi vuto la impso mu phwando la medicament "Cefoperazone Sulbactam" pamodzi ndi aminoglycosides ndi okodzetsa zinadzala chitukuko cha nephrotoxicity.

Pa mankhwala ndi "Cefoperazone" osafunika kumwa mowa, mwinamwake izo zikhoza zizindikiro zotsatirazi:

• Nseru.
• Kusanza.
• Aakulu mutu.
• Tachycardia.
• kutsitsa magazi.
• ululu m'mimba.

Musanayambe chithandizo ndi mankhwala, muyenera kudziwitsa dokotala wanu za mankhwala onse zikutengedwa pa mphindi.

Kodi kuchita ngati muli contraindicated amatanthauza "Cefoperazone"? Analogs mwina m'malo mwake.

Ena mokoma ntchito mankhwala

Pa mankhwala ndi mankhwala ayenera kusamala makamaka kwa anthu odwala amene ali thupi lawo siligwirizana nthawi zambiri anaona. Chiopsezo cha kuzindikira ichi kuchuluka ana amakumana ndi ngakhale chakupha. Ngati pa mankhwala anati ngakhale zazing'ono thupi lawo siligwirizana, mankhwala "Cefoperazone + Sulbactam" ayenera kukwezedwa yomweyo ndipo m'malo mwa njira zina.

Ngati wodwalayo digiri choopsa cha kutsekeka kwa thirakiti biliary, matenda a chiwindi ndi impso, pamafunika munthu mavuto mlingo kusintha. Pamaso pa kuwonongeka aimpso ndi kwa chiwindi ayenera nthawi zonse kuyan'anila ndende ya mankhwala yogwira mankhwala seramu wa. Ngakhale popanda ulamuliro mlingo sayenera upambana 2 gm patsiku.

Odwala ena pa mankhwala ndi "Cefoperazone" osauka vitamini K akusowa Nthawi zambiri vutoli anaonekera amene amadya zakudya zosalongosoka, malabsorption, kapena kuvutika kwa nthawi yaitali pa kudya mtsempha. Odwala amene akulandira mankhwala ndi anticoagulants, kufunika zonse kuwunika kwa prothrombin nthawi, ndipo ngati n'koyenera, adzaika kudya zina vitamini K.

Ngati mukufuna njira yaitali mankhwala, "Cefoperazone", n'zotheka kuonjezera yaying'ono-zamoyo zomwe si atengeke medicament izi. Kumafuna polojekiti nthawi zizindikiro za ntchito kwa ziwalo, makamaka chiwindi, impso ndi hematopoiesis. Zimenezi n'zofunika kwambiri makamaka pa matenda a neonates, makanda ana ndi makanda msanga.

Pa mankhwala sayenera galimoto ndi ntchito zimene amafuna ndende kwambiri.

analogues mankhwala

Ngati tikambirana mankhwala aliwonse, magulu awiri akhoza otchulidwa kukonzekera iye analogs ndi ofanana. Pakuti ofanana monga mankhwala kuti zikuchokera awo yemweyo yogwira pophika. Pakuti "Cefoperazone" mankhwala, awa:

• "Bakperazon".
• "Sulzontsef".
• "Sulmomer".
• "Sultsef".
• "Tsebaneks".
• "Paktotsef" ndi ena.

Ngati Tikayerekeza medicament "Cefoperazone" analogs akhoza kukhala zigawo zambiri zina, amene pamodzi ndi zinthu zofunika ndi zotsatira zosiyana pang'ono. N'chifukwa chake kusankha mankhwala ayenera kulankhula mosamala ndi kuzilandira yekha mankhwala.

gulu lina la analogues ndi mankhwala ndi chimodzimodzi kanthu pharmacological. Ngati inu kutenga mankhwala "Cefoperazone + Sulbactam" analogues wa gulu awa:

• Ufa "Azaran" anthu jakisoni mtsempha.
• "Axons."
• Ufa jekeseni "Bestum".
• "Vitsef".
• "Klaforan".

• "Kefoteks".
• "Tsedeks" makapisozi.
• "Tsemideksor" (mapiritsi).
• "Tsefantral" ndi ena ambiri.

Ngakhale ndi zotsatira chomwecho pharmacological mankhwala chifukwa cha zinthu zosiyanasiyana yogwira angakhale ndi zotsatira zosiyana pa thupi, kotero musati kusankha mankhwala awo, zochokera malangizo ntchito.

umboni

Odwala amene sanali kamodzi agwiritsa ntchito "Cefoperazone + Sulbactam" mankhwala zochizira matenda opatsirana anati Mwachangu ake okwezeka. Ambiri amanena kuti matenda genitourinary n'ngochiritsika mwamsanga ndipo popanda matendawo.

Momma ana kusiya ovomereza mankhwala "Cefoperazone" ndemanga mwachilungamo positive. Iwo anaona kuti ana kulekerera mankhwala bwino ngakhale pamaso pa co-morbidities. Iwo ayenera kukumbukira kuti mankhwala ayenera kuchitidwa kokha pa chipatala, makamaka ana.

The malowedwe a maantibayotiki aliyense amafuna kwambiri kuti ntchito ya dongosolo m'mimba. Kukhala bwino microflora, ndi wolakalakika imodzi kulandira mankhwala oyenerera, mwachitsanzo, "Linex". funso limeneli nthawi zonse kukambirana ndi dokotala.