Chloramphenicol (piritsi) - malangizo Buku

Chidule kukonzekera ndi chloramphenicol mlingo mawonekedwe - mapiritsi, TACHIMATA mapiritsi kapena makapisozi.

kapangidwe

Yogwira mankhwala:

• ndi chloramphenicol - 250/500 mg (piritsi 1)

Excipients:

• kashiamu stearate;
• mbatata wowuma.

The kanthu pharmacological wa ndi chloramphenicol mankhwala

Chloramphenicol Mapale ndi yotakata-sipekitiramu mankhwala, amene ali polimbana ndi kuchuluka kwa galamu HIV ndi galamu alibe mabakiteriya onse. Komanso, yogwira mankhwala akhoza kuchita pa mitundu yomwe ndi kugonjetsedwa ndi antibayotiki zotsatirazi - penicillin, sulfonamides, streptomycin.

Mankhwala amachita pa bakiteriya ndi kusokoneza mapuloteni kaphatikizidwe, motero mu Mlingo achire, mankhwala kumasintha kanthu bacteriostatic.

Kulimbikira kuti mankhwala mu tizilombo wosakwiya, ndipo motero amachita mtanda zosagwira kuti maantibayotiki ena dongosolo ofanana.

kukonzekera zizindikiro ndi chloramphenicol

Miyala ya mankhwala ntchito zingapo za matenda amene angathe kuyamba chifukwa cha tizilombo toyambitsa:

• paratyphoid;
• typhoid;
• salmonellosis;
• shigellosis;
• brucellosis;
• rickettsial matenda;
• tularemia.

Zotsatira zoyipa za mankhwala ndi chloramphenicol

Pamene mankhwala poizoni, kapena kungoti ngati muli hypersensitive zingakhudze mmene ena mbali, amene ikukhudzana kachitidwe zosiyanasiyana za thupi.

Zotsatira zoyipa zokhudzana ndi magazi:

• thrombocytopenia;
• leukopenia;
• reticulocytopenia;
• ndichepe kuchuluka kwa hemoglobin m'magazi;
• aplastic magazi m'thupi.

Zotsatira zoyipa zokhudzana thirakiti m'mimba ndipo zimagwira ntchito zosiyanasiyana mucous:

• kusanza;
• nseru;
• bloating;
• m'mimba;
• mucosal irritations;
• stomatitis;
• glossitis;
• Chotupa chija;
• zisadzachitikenso wa matenda a mafangasi.

Zotsatira zoyipa zokhudzana chapakati mantha dongosolo:

• kumva imfa (kusintha);
• kuyerekezera zinthu m'maganizo;
• chamawonedwe neuritis;
• neuritis zotumphukira;
• encephalopathy;
• maganizo;
• mutu.

Zotsatira zoyipa zokhudza thupi lawo siligwirizana:

• malungo;
• zotupa pa khungu;
• anaphylaxis;
• Angioedema.

Contraindications ntchito yokonza ndi chloramphenicol

Mapiritsi a mankhwala ali osavomerezeka mu ngati wodwalayo chimodzi kapena zingapo mwa zinthu zotsatirazi (limati):

• matenda magazi, kuphatikizapo chopinga magazi;
• psoriasis;
• matenda a mafangasi a khungu;
• chikanga;
• mkhutu chiwindi ntchito;
• ARI;
• Mimba ndi mkaka wa m'mawere;
• porphyria;
• zaka zaka 3.

mankhwala ambiri osokoneza bongo

Pankhaniyi cha mankhwala osokoneza bongo, ngati mankhwala ntchito chloramphenicol, mwina zizindikiro zotsatirazi - zotheka mavuto ziwalo hematopoietic ndi kachitidwe, omwe kawirikawiri pozigwiritsa ntchito yaitali mlingo waukulu kwambiri mankhwala. Zovuta zimachitika zilonda zapakhosi, wotumbululuka khungu, magazi, malungo ndi ambiri kufooka kwa thupi.

Ana, ndi ambiri osokoneza zingaoneke:

• kusanza;
• bloating;
• imvi khungu;
• arrhythmic kupuma;
• hypothermia;
• mtima kugwa.

Pofuna kuchotsa zizindikiro zimenezi, muyenera yomweyo pambuyo matenda awo kusiya kumwa mankhwala, kuchapa m'mimba, tinayamba kulandira sorbents ndi kuyamba mankhwala symptomatic akamavutika.

mogwirizana mankhwala ndi mankhwala ndi chloramphenicol

Miyalayo sayenera kumwedwa kukachitika kuti wodwala anatumizidwa mankhwala kumabwezera mmbuyo mapangidwe magazi, ndi zida makamaka monga cytostatics, opangidwa kuchokera pyrazolone ndi sulfonamides, ngati kuwapatsa mpata, ndiye m'pofunika kusiya ntchito chloramphenicol ndi kumupeza njira ina.

Mankhwala monga phenobarbital rifampin, rifabutin ndi amachepetsa kwambiri ndende ndi mphamvu ya chloramphenicol.

Mankhwala amachepetsa zotsatira antibacterial wa penicillin ndi cephalosporins. Komanso, akhoza kuchepetsa efficacy wa mankhwalawa, lincomycin, ndi clindamycin, ndi.