Epinephrine: ndi chiyani? Epinephrine: malangizo ogwiritsira ntchito ndi ndemanga

Epinephrine - ndi chiyani? Tidzakambirana za izi mu nkhaniyi. Komanso, mudzaphunzira za cholinga chomwe mankhwalawa amagwiritsidwira ntchito, kaya ali ndi zotsutsana ndi zotsatira zake.

Chemical katundu

Epinephrine - ndi chiyani? Kodi ichi ndi chiani? Malinga ndi akatswiri, izi ndi chimodzi mwa ziwalo zofunika kwambiri za m'mimba, zomwe zimapangidwa ndi ma glands adrenal. Dzina lina la chinthu ichi ndi adrenaline.

Malingana ndi makina a mankhwala, chinthu chomwe chimaphatikizapo chimatanthawuza ma catecholamines. Choncho, Epinephrine ndizopanga adrenaline.

Mu chikhalidwe cha thupi, chigawo ichi chiri mu ziwalo zosiyanasiyana ndi matenda. Zimapangidwa ndi minofu ya chromaffin.

Epinephrine, malangizo ogwiritsira ntchito omwe akufotokozedwa m'munsimu, amakhudza beta ndi alpha-adrenergic receptors, komanso amachititsa chidwi chachisoni cha mitsempha.

Ndikumva kupanikizika, kudzidzidzimuka, nkhawa, mantha, kutentha ndi kuvulala kosiyanasiyana, adrenaline m'thupi imakula kwambiri. Zimatenga mbali mu mitundu yonse ya kagayidwe ka shuga, komanso zimakhudza mlingo wa shuga ndi minofu ya metabolism, imathandizira gluconeogenesis, glycogenolysis, mapuloteni a katemera ndi njira ya kuwonongeka kwa mafuta, amalepheretsa kugwiritsidwa ntchito kwa glycogen mu minofu ndi matenda a chiwindi.

Fomu ya vuto

Epinephrine: Kodi ndi yotani ndipo imapangidwa bwanji? Pali mitundu yosiyana ya epinephrine. Amagulitsidwa ngati madontho kapena mapiritsi a homeopathic otsogolera pakamwa, komanso zothetsera jekeseni ndi ntchito zamagetsi. Kuonjezera apo, chinthu ichi chimapangidwa mwa mawonekedwe a mankhwala-tincture kapena mankhwala-powder.

Pharmacological katundu

Kodi katundu wa epinephrine ndi wotani? Ndi chiyani icho, ife tawuzidwa pamwambapa. Malingana ndi akatswiri, mankhwalawa ali ndi hyperglycemic, hypertensive, vasoconstrictive, bronchodilator ndi odana ndi zotsegula zochita.

Mapangidwe a adrenaline pamtundu wa maselo amachititsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda timene timayambitsa matendawa amachititsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda. Mankhwalawa amachititsa kuti magazi aziponderezedwa, amachepetsanso ziwalo zamkati, khungu, ziwalo zam'mimba, mitsempha ya zigoba, komanso amachepetsa ziwiya za ubongo.

Zida za chida

Epinephrine hydrochloride imathetsa minofu ya matumbo ndi bronchi. Kuonjezera apo, kumapangitsa kuti ophunzira apitirize kuyambiranso.

Kugwiritsa ntchito mankhwala omwe ali ndi mankhwalawa kumawonjezera kufunika kwa mtima mu mpweya ndipo kumaletsa kukula kwa edema ya bronchioles. Komanso, mankhwalawa amachepetsa kuchuluka kwa chiwerengero cha anesthetics, amachepetsa poizoni ndikupitiriza kuchuluka kwa zochita za anesthesia.

Zisonyezo

Kodi ntchito ya epinephrine ndi yotani? Kugwiritsiridwa ntchito kwa wothandizirayi kumasonyezedwa kuti kuthetsa vutoli lomwe lakhalapo chifukwa cha kuika magazi, kuwonetsa mankhwala, kugwiritsa ntchito mankhwala osiyanasiyana, kulumidwa kwa tizilombo kapena kuyang'anira zowonongeka.

Komanso, mankhwalawa amagwiritsidwa ntchito pazifukwa zotsatirazi:

• Pofuna kuthandizidwa ndi matenda a mphumu;
• Ndi pamodzi ndi asystole;
• Kuchulukitsa zochita za anesthetics kumidzi;
• Ndi bronchospasm, yomwe inachitika panthawi yopweteka;
• Pa hypotension, osapereka chithandizo mwa mankhwala osinthika m'malo;
• Kuchiza chithandizo cha hypoglycemia chochulukitsidwa ndi kupitirira muyeso wa insulini;
• Kuchetsa magazi;
• Ndi glaucoma yotseguka kuti cholinga cha kuchepetsa wophunzira;
• Pa chithandizo cha priapism.

Contraindications

Akatswiri a Epinephrine hydrochloride samalimbikitsa kugwiritsa ntchito pamene:

• Hypersensitivity, kuthamanga kwa magazi;
• Mimba;
• Hypertrophic cardiomyopathy ;
• IHD ndi tachyarrhymimias;
• Anthu okhala ndi fibrillation ya ventricular;
• Pheochromocytoma;
• Kuyamwitsa.

Chisamaliro chiyenera kutengedwa pamene odwala ali ndi zifukwa zotsatirazi:

• Hypercapnia;
• Ventricular arrhythmia, fibrillation yamagazi ndi hypoxia;
• Kupatsirana kwapachirombo;
• Kusokonezeka, kukhumudwa kapena kukhumudwa kwa mtima ;
• Chonchi;
• Matenda osadziwika a mitsempha ya mitsempha;
• Matenda a Raynaud ;
• Matenda a Atherosclerosis kapena Matenda a Buerger ;
• Matenda a shuga;
• Matenda a atherosclerosis;
• Matenda a Parkinson;
• Chilombo cha shuga ndi kutseka glaucoma;
• Ntchito yowonjezereka;
• Kutentha thupi kwa prostate gland;
• Anthu omwe ali ndi metabolic acidosis;
• Pambuyo pa kuvulala kozizira;
• Pambuyo pa matenda a myocardial infarction;
• Odwala ndi okalamba.

Epinephrine: malangizo ogwiritsidwa ntchito

Kawirikawiri mankhwala osokoneza bongo a epinephrine amatengedwera mwachangu kapena pansi. Komanso, mankhwalawa amalowa mkati mwawo.

Pofuna kuthandizidwa ndi matenda a mphumu, mankhwala osokoneza bongo amathandizidwa ndi subcutaneously mu kuchuluka kwa 0.3-0.5 mg.

Kuchulukitsa nthawi ya anesthetics kumidzi, mankhwalawa amalembedwa pa 5 μg / ml.

Kuti asiye magazi, epinephrine imagwiritsidwa ntchito pamwamba. Chombo, choviikidwa mu njira, chimagwiritsidwa ntchito ku malo owonongeka.

Ndi asystole, majekisoni osakanikirana amawonetsedwa, komanso jekeseni wamatenda mkati mwa kubwezeretsedwa.

Mankhwala a glacoma otseguka amapezeka poika 1-2% yankho mu diso lomwe likukhudzidwa 1 dontho kawiri pa tsiku.

Zovuta zochitika

Malingana ndi madokotala, epinephrine ikhoza kuyambitsa:

• Angina pectoris, tachycardia, palpitations, bradycardia, kuchepa kapena kuwonjezeka kwa kuthamanga kwa magazi;
• Ventricular arrhythmia, kupweteka pachifuwa, mtima wa arrhythmia;
• Nkhawa, kunjenjemera, chizungulire ndi kumutu;
• Kumverera kwa kutopa, kumverera kotentha kapena kutentha, mantha;
• Kusokonezeka, NA chisangalalo, kusinthasintha kwapadera, kusokonezeka maganizo ndi zina zotero.

Analog

Kodi tingabwezere bwanji njira zomwe tikuziganizira? Epinephrine imapezeka mu mankhwala monga epinephrine hydrotartrate, adrenaline, adrenaline hydrotartrate, adrenaline tartrate, adrenaline hydrochloride - Vial.

Tiyeneranso kukumbukira kuti articaine ndi epinephrine ndi mbali ya Septanest ndi adrenaline, Alfacaine JV, Articaine INIBSA, Artifrin, Primacaine ndi adrenaline, Ultrakaina D-S, Ubistezina, Brilocaine Adrenaline "," Artikina DF "," Cytokartina "," Artikina Perrel "ndi adrenaline.

Ndemanga

Pali ndemanga zochepa chabe za chinthu chomwe chilipo. Ichi ndi chifukwa chakuti mankhwalawa amagwiritsidwa ntchito pokhapokha ngati akudwala matendawa.

Malinga ndi akatswiri, epinephrine ndi chinthu chofunika kwambiri chomwe chimathandiza kupulumutsa moyo wa wodwalayo.