Lincomycin hydrochloride.

Ambiri samakayikira kuti mankhwala ambiri oteteza mabakiteriya amadziwika kuti amatha. Komabe, kusiyana kotereku sikugwirizanitsidwe ndi chitukuko cha mankhwala ndi pharmacology, komanso chifukwa chosowa anthu chifukwa cha mankhwalawa.

Chovuta chachikulu cha antibiotic iliyonse ndikumana nawo. Ndalama zina zimatha kutengedwa m'magulu angapo, ndipo mphamvu zawo sizitha kuchepa, koma palinso zomwe zimayambitsa kusamvera kwa zomera kuchokera tsiku loyamba lololedwa.

Lincomycin hydrochloride ndi mankhwala osokoneza bongo omwe ali m'gulu la lincosamides. Zimapangidwa ndi gulu la actinomycetes ndi tizilombo tina tofanana ndi katundu.

Pamene munthu alowa m'thupi la munthu, mankhwala amatha kudutsa mndandanda wa masinthidwe. Choyamba, chipolopolo cha piritsi kapena capsule m'mimba chimawonongeka, ndipo kenaka m'mimba yaing'ono mankhwalawa amagawidwa kukhala tizilombo ting'onoting'ono tomwe timalowa magazi. Pogwiritsa ntchito magazi, mankhwalawa amalowa m'maganizo otupa ndipo amamangiriza ku pyroxisome yaikulu ya ribosomes. M'mawu ena, lincomycin hydrochloride imasokoneza zochita zonse za ntchito yofunikira ya mabakiteriya, omwe amatsogolera ku imfa yawo. Theka la moyo wa mankhwalawa kuchokera m'thupi ndi pafupi maola asanu, motero, patapita nthawi ndikofunikira kufalitsa mlingo wachiwiri wa mankhwala.

Patangopita maola angapo pambuyo pa kayendetsedwe ka kayendedwe kameneka, chiwerengero chachikulu cha mankhwala a lincomycin akupezeka m'magazi. Ndi bwino kutenga lincomycin hydrochloride ora limodzi musanadye chakudya kapena muyeso yofanana pambuyo pake, kuyambira Kutenga limodzi ndi zakudya kumachepetsa kutengeka kwa mankhwala ndi 50%.

Kusintha kwa mavitamini mu mankhwala osokoneza bongo makamaka mu chiwindi, ndipo kumadetsedwa ndi impso, motero, kuphwanya ntchito ya ziwalo izi kungachititse kuchedwa kwa mankhwala owonongeka a antibiotic mu thupi - ndi chitukuko cha machitidwe owopsa.

Tiyenera kukumbukira kuti mankhwalawa ali ndi zotsatira zofanana: bactericidal ndi bacteriostatic. Mmodzi wa iwo akhoza kulamulira wina kapena ayi - zonse zimadalira mphamvu ya tizilombo tochepa ndi mlingo wa mankhwala. Ndipotu, nthawi yofunika kwambiri ndi nthawi ya mankhwala, komanso kugwirizana kwake ndi mankhwala ena.

Lincomycin hydrochloride ali ndi mphamvu zambiri zochiritsira motsutsana ndi Gram-positive osati spore-kupanga anaerobic mabakiteriya, koma zotsatira zake zabwino pa spore anaerobes zinadziwikiranso.

Chizindikiro cha mankhwala:

- Matenda a m'mwamba ndi otsika m'mimba mwa chiwopsezo;

-pathology wa ENT ziwalo (otitis, sinusitis, pharyngitis ndi laryngitis);

- zilonda zamatenda komanso zamtundu wa khungu, ziphuphu zofewa;

- kamwazi ndi chifuwa chofiira.

Lincomycin hydrochloride imaperekedwa kwa akuluakulu pa 1.5 magalamu pa tsiku, omwe amagawanika mu magawo atatu ogawanika (2 makapisozi atatu pa tsiku). Pakati pa maola 8 pakati pa kutenga capsules ayenera kuwonedwa. Kugwiritsa ntchito mankhwala osagwiritsidwa ntchito mosaletsa kungayambitse zotsatira zambiri. Ndi matenda oopsa komanso osatha, mukhoza kuwonjezera mlingo wa mankhwala tsiku lililonse mpaka 2 magalamu.

Ana osakwanitsa zaka 14, lincomycin (makapisozi a 500 mg) amalembedwa molingana ndi kulemera kwake, 30 mg pa kilogalamu iliyonse mu magawo anayi ogawidwa, ngati kuli kotheka, mukhoza kuwonjezera mlingo wa 60 mg pa kilogalamu yolemera.

Njira yonseyi imachokera ku masiku 10 mpaka masabata atatu, malingana ndi kuopsa kwa matenda komanso chidziwitso cha mthupi .

Odwala ena angawonongeke atatha kumwa mankhwalawa:

- kusanza ndi kutsekula m'mimba;

- khungu pa khungu ndi mucous membrane;

- jaundice;

- Kuchepetsa magazi;

- superinfection.

Ndikoyenera kumwa mankhwala oletsa antibacterial kokha malinga ndi mankhwala a dokotala mu mlingo woyenerera ndi kusunga nthawi ya pakati pa mapepala. Ngati zizindikiro kapena zizindikiro zosayembekezereka zimachitika mutatha kumwa mankhwalawa, nthawi yomweyo mufunseni dokotala ndipo musagwiritse ntchito musanayambe uphungu.