Lupus anticoagulant - mmene oopsa

Pa clotting magazi angakhudzidwe ndi magawo ambiri, amene anatsimikiza ndi kuwunika amuzolengedwa magazi ndi kuphunzira coagulation, koma Mulimonsemo m'pofunika kukumbukira kuti zizindikiro zonse ayenera kuunikira dokotala ndi kudalira mu nkhani iyi yokha kuwunika chizindikiro chimodzi, ndipo pa zotsatira za kafukufuku mwatsatanetsatane. Nthawi zina, magazi coagulation ndi dongosolo anticoagulation za kuwunika ali kuchita ndi mayesero immunological Mwachitsanzo, kupereka magazi kwa chitetezo kwa cardiolipin ndi lupus anticoagulant.

ndi lupus anticoagulant ndi kufunika kwake mu thupi Kodi

M'mikhalidwe wabwinobwino, magazi coagulation ndi machitidwe anticoagulation ali mu mgwirizano, - flowability magazi anapitiriza potero mu mtsempha, pakalibe kuwonongeka ndi thrombus mapangidwe ndi kuvulala ndi mabala a kulikonse. Motero, anthu ambiri zinthu zina mu seramu magazi ayenera ziwonjezeke kwa angalipirire ndi zina - yekha mu nkhani iyi ndi thrombosis zotheka chenjezo. Koma thupi la munthu angalipirire kusintha kokha malire zina, kenako apo pakubwera nthawi imene ngakhale anali ndi chizolowezi thrombosis angakhale chifukwa cha magazi - zinthu amachititsa clotting magazi, musati mukhale mu seramu wa. Ndi zinthu zimene zingachititse matenda coagulation monga lupus anticoagulant - chinthu chapadera cha mapuloteni chikhalidwe, m'dziko la immunoglobulin anthu.

Yopangidwa chitetezo awa komanso chitetezo kwa cardiolipin ndi phospholipids ambiri, mu maselo a chitetezo cha m'thupi, ndipo ambiri a zinthu izi mu magazi anali wapezeka zosiyanasiyana matenda autoimmune. Koma vuto lagona pa choona kuti lupus anticoagulant zabwino woyembekezera, mwina chifukwa cha mavuto osiyanasiyana pa mbali ya mayi oyembekezerayo, ndi kwa mwana wosabadwayo. Iwo ayenera kumvetsa kuti kudziwika lupus anticoagulant pakalibe chitetezo ndisiyane DNA mtima, phospholipids, cardiolipin kulankhula kokha kwa kuthekera kwa zotsatirapo zimenezi ndi kufunika kuwayang'anira nthaŵi zonse mankhwala wodwala.

Kumbukirani kuti lupus anticoagulant, umene uli ponseponse ndi mwazi seramu ranges kuchokera 0,8 kuti 1.2 mayunitsi lachabechabe, si mokwanira odalirika chizindikiro. Choncho, kudziwika milingo okwera kapena phunziro ngakhale wofooka chifukwa ndi zofunika kuchita kuipidwa ndi coagulation ayenera chimatanthauza D-dimer, coagulation nthawi (APTT) ndipo mwina ambiri zizindikiro kuphunzira - zimadalira ulosiwu, ndi njira zotheka mankhwala wodwala.

Lupus anticoagulant - pamene kufufuza pakufunika

Zichitike magazi lupus anticoagulant ukafunidwe osati kwa amayi apakati. kusanthula izi imagwiridwa ndi anatumizidwa odwala amene isanafike zaka 40 anaonekera wolumikizira ndi venous thrombosis chilichonse malo, thromboembolism, hemorrhagic mwadzidzidzi kapena ischemic sitiroko popanda pamaso pa matenda awo amene angathe makope oziziritsa (wolumikizira oopsa, atherosclerotic cardio). Chapadera ndi atsikana, amene m'moyo wawo akhala milandu imfa yadzidzidzi ya mwana wosabadwayo pa siteji iliyonse ya mimba, pakalibe matenda majini ndi matenda yoopsa. Only ndi kuwunika zonse magawo coagulation, coagulate lupus, chitetezo kwa phospholipids ndi cardiolipin akhoza kusankha mankhwala - yekha mu nkhani iyi n'zotheka kupewa kudwala matenda a magazi.