"Ortanol" chimene chimathandiza, malangizo ntchito kwenikweni

ndi mankhwala "Ortanol" n'chiyani? Kuchokera pa zimene zimathandiza mankhwala? Mayankho a mafunso amenewa amapezeka pansipa. Komanso, ife azipereka mtengo wa mankhwala anati, contraindications ake, analogs ndi kumasula mawonekedwe.

Kenaka mankhwala chake zikuchokera, maonekedwe, mawonekedwe

Kukonzekera "Ortanol" analengedwa mu mawonekedwe a makapisozi zovuta kukula № № 1 kapena 2. Izi zikutanthauza ali ndi mtundu woyera komanso lolembedwa «OME 20» kapena «OME 40 '(malingana mlingo). makapisozi zili mankhwala umaimira pellets chikasu.

Zimenezi zimaphatikizapo mankhwala "Ortanol"? Reviews amati mankhwala ikupezeka ankaona omeprazole mankhwala. Ndiponso ali zigawo wothandiza monga ndi sodium croscarmellose, otsika mmalo giproloza, lactose anhydrous, microcrystalline mapadi, hypromellose phthalate, povidone, polysorbate 80, talc ndi dibutyl sebacate.

The zikuchokera chipolopolo kapisozi monga: propylene glycol, hypromellose, butanol, carrageenan, Mowa anhydrous, shellac, mankhwala enaake potassium isopropanol anhydrous, titaniyamu dioxide, Inki yolembera inscribing ndi madzi.

Chogulitsa medicament "Ortanol" (kapisozi) akulowa chithuza, mmatumba mu makatoni.

Pharmacological ntchito mankhwala

ndi "Ortanol" (zimene zimathandiza mankhwalawa, mudzaphunzila pansipa) ndi chiyani? Malinga ndi malangizo, mankhwala ndi woletsa wa purotoni mpope. Amachepetsa yopanga asidi, ie, kubweza ntchito ya K + -H + -ATPase m'mimba, kapena m'malo maselo wake parietal. Ndiponso midadada chomaliza katulutsidwe chapamimba acid.

Mankhwala "Ortanol", mtengo wa amene ali m'munsiwa ndi prodrug. Chida ichi ndi adamulowetsa mu sing'anga acidic wa tubules (secretory) maselo parietal. Komanso kumachepetsa inalimbikitsa ndi woyambira katulutsidwe mosaganizira chikhalidwe cha nzothandiza lapansi.

Antisecretory katundu wa medicament ndi kumachitika mu mphindi 60 choyamba (pazipita pambuyo maola 2). Chopinga 50% ya katulutsidwe pazipita kukupitirirabe tsiku.

A mlingo umodzi wa mankhwala amapereka bwino ndipo mofulumira yimitsira nthawi yausiku ndipo masana chapamimba katulutsidwe. pazipita ake akafika pa 4 mankhwala ndi kutha atapita masiku atatu pambuyo chithandizo.

Kayendedwe katundu wa mankhwala

Pa polandira "Ortanol" kukonzekera izo amakwaniritsa mkulu mayamwidwe. magawanidwe Peak wa omeprazole mu magazi anaona pambuyo maola 0.5-3. The bioavailability mtheradi wa mankhwala ndi 30-40%, ndi kugwirizana medicament ndi mapuloteni plasma - 95%.

Omeprazole kagayidwe mu chiwindi kupanga asanu opangidwa kuchokera pharmacologically kulalikira.

Hafu ya moyo mankhwala nthawi maola 0.5-1. Linanena bungwe monga ena ofanana ndi impso (70-76%) ndi limodzi ya ndulu (18-24%).

Anthu aakulu matenda chiwindi bioavailability wa mankhwala ali kwambiri kuchuluka, ndi madzi a m'magazi theka moyo ukufika maola 3.

Odwala ndi aakulu excretion matenda a impso kubweza. Izi zimachitika yolingana ndi kuchepetsa CC.

Medicament "Ortanol": zimene zimathandiza?

Ankaona kukonzekera akusonyeza ntchito matenda otsatirawa:

• Reflux esophagitis;
• m'mimba matupi matenda chilonda (kuphatikizapo kupewa muyambirenso);
• limati hypersecretory (nkhawa zilonda za intestine ndi, matenda Zollinger-Ellison, zokhudza zonse mastocytosis, polyendocrine adenomatosis);
• atheretu Helicobacter pylori matenda anthu odwala matenda anam'peza wa kapepalako m'mimba (mu mankhwala osakaniza);

• mankhwala ndi kupewa m'mimba mucosal ziwalo kuwonongeka amene amayamba NSAID (mucosal kukokoloka, dyspepsia, chironda chachikulu).

Ziletso mankhwala ntchito

Kodi contraindications mankhwala ali "Ortanol" (zimene zimapangitsa chida ichi, talankhula pamwamba)? Malinga ndi malangizo amene ankaona mankhwala sangathe ntchito pamene:

• mkaka wa m'mawere;
• paubwana;
• hypersensitivity kwa mankhwala mankhwala.

Ndi wapadera kusamala ankaona mankhwala analamula kuti kulephera aimpso ndi chiwindi.

Mankhwala "Ortanol" mawu

Izi mankhwala Kwalamulidwa mkati yekha. Amatengedwa chabe pamaso chakudya (zambiri m'mawa pamaso chakudya).

The kapisozi ndi mankhwala ndi kuwameza lonse ndi madzi. Zikatero, ngati wodwala akulephera kugwiritsa ntchito mankhwala kwathunthu, nkhani zake akhoza zidzasungunuka mu pang'ono si acidic kwambiri madzi.

Mlingo wa mankhwala zimadalira umboni.

Pamene zilonda 12 mmatumbo chilonda medicament chikuyendetsedwera pa 20 mg wa kamodzi pa tsiku kwa masabata awiri. Kukachitika kuti pambuyo chaka choyamba wathunthu amamuyambitsa timabala zimachokeradi, kachiwiri yoikidwiratu iwiri mankhwala.

Mu anam'peza matenda kuichiza wothandizila ili bwino kutenga mlingo wa mg ndi 40 kamodzi pa tsiku. The njira ya mankhwala ndi mankhwala akhoza anawonjezera kuti milungu inayi.

Makapisozi "Ortanol" zikuonetsa omwe ali pamwambawa, anam'peza zotupa za m'mimba kutenga 20 mg wa kamodzi tsiku lililonse kwa masabata anayi. Ngati amamuyambitsa timabala zimachokeradi pambuyo chaka zapita, kukonzanso yoikidwiratu zinayi sabata mankhwala. Mu chapamimba chilonda, kuichiza, mankhwala osavomerezeka kutenga muyezo wa mg ndi 40 kamodzi pa tsiku (mlingo wa milungu eyiti).

Atheretu Helicobacter pylori ikuchitika osakaniza mankhwala. Pankhaniyi, medicament ndi kutumikiridwa pa 20 mg wa kawiri pa tsiku pamaso chakudya (kwa masabata awiri) osakaniza ndi wothandizila antibacterial.

Pamene Reflux esophagitis mankhwala tikulimbikitsidwa kugwiritsa ntchito ndalama 20 mg (kamodzi) kwa masabata anayi. Ngati njira imeneyi mankhwala si abwino malizitsani mankhwala, wodwalayo Kwalamulidwa njira chachiwiri (masabata anayi). Mu aakulu chithandizo Reflux esophagitis chida ichi anawonjezera kuti masabata asanu ndi atatu.

Pamene hypersecretory boma imatengedwa mankhwala kwa kutentha kutumikiridwa payekha. Analimbikitsa kuyambira mlingo akuluakulu 60 mg (kamodzi), ndi pazipita - 120 mg.

Poika mankhwala oposa 80 mg pa tsiku, lagawidwa magawo angapo.

Pamene m'mimba mucosa limba kuwonongeka, amene amayamba ndi NSAID, komanso kupewa kapisozi "Ortanol" kulengeza ntchito mlingo wa mg ndi 20 tsiku lililonse, asanayambe kudya (kwa nthawi yonse ya NSAID mankhwala).

Yosamalira anthu okalamba ndi anthu aakulu chiwindi matenda pazipita mlingo tsiku ndi 20 mg.

Kwa odwala ndi mkhutu impso ntchito mlingo kusintha chofunika.

mbali zochitika

zosiyanasiyana zimene zokayikitsa kuchititsa mankhwala "Ortanol"? Reviews kunena izi mavuto:

• mutu, amaona masomphenya, chizungulire, erythema multiforme, paresthesia;
• kusinza, nseru, kukoma chisokonezo, kutsekula m'mimba, kusowa tulo, flatulence;
• mukubwadamuka, youma pakamwa, maganizo, matenda, kusintha chisokonezo maganizo
• encephalopathy, gynecomastia, matenda a chiwindi, zotumphukira edema, kusanza ndi photosensitivity;
• ululu m'mimba, thrombocytopenia, kudzimbidwa, pancytopenia, kuchuluka kwa ntchito zamchere phosphatase ndi chiwindi transaminase;
• khungu kuyabwa, mkhutu chiwindi ntchito, kufooka kwa thupi, mapangidwe cysts chapamimba glandular;
• alopecia, eosinophilia, kuchuluka thukuta, bronchospasm, agranulocytosis, angioedema;
• leukopenia, myalgia, malungo, arthralgia, zochita anaphylactoid, urticaria, interstitial nephritis.

Zotsatira zoyipa zimene zimachitika mu ntchito wothandizila ndi malipoti wofatsa ndi kufupika m'chilengedwe.

Nthawi cha mankhwala osokoneza bongo

Pamene kumwa mankhwala kutentha wodwalayo zotsatirazi zizindikiro kumachitika: mutu, pakamwa youma, tachycardia, kugona, nseru, kusawona bwino, kusanza, kusokonezeka maganizo, kuchuluka thukuta.

Zikatero, symptomatic mankhwala.

Mwanjira mankhwala

Pamodzi ndi chikuonetseratu omeprazole kuchuluka theka moyo ndi kuchuluka ndende "ntchito diazepam", "warfarin", "phenytoin", komanso mankhwala ena amene zimapukusidwa mu chiwindi ndi isoenzyme CYP2C19.

Mayamwidwe njira akhoza kukhumudwa, ndi bioavailability amene anatsimikiza ndi acidity wa madzi chapamimba (mwachitsanzo, "Itraconazole" "ketoconazole" esters wa ampicillin "cyanocobalamin" ndi salt chitsulo).

The bioavailability wa digoxin pamene co-kutumikiridwa ndi omeprazole ndi chinawonjezeka ndi 10%.

Ankaona mankhwala timapitiriza zotsatira ochepetsera pa dongosolo mankhwala ena hematopoietic.

No kukomoka ankachita chidwi mankhwala ndi mankhwala mankhwala ochotsa asidi, tiyi kapena khofi, "theophylline", "Quinidine", "propranolol", Mowa, lidocaine wa ndi "metoprolol" sipakhala.

ayamikira yeniyeni

chotupa chija Tisawasale musanayambe mankhwala ndi omeprazole. Ichi ndi chifukwa chakuti mankhwala kungathe kubisa zizindikiro ndipo sachedwa olondola matenda mawu.

Panopa, palibe deta pa zotsatira za ndalama pa luso munthu kulamulira njira ndi kuyendetsa galimoto.

Mtengo ndi analogues

Zingati izi mankhwala odana ndi chilonda, monga "Ortanol"? Mtengo wa mankhwala ndi za 100-115 rubles. Pakuti ogula kwambiri, mtengo wa ichi n'cholandirika.

Kodi m'malo mankhwala "Ortanol"? Analogs kukonzekera lino anapereka mu mawonekedwe a "omez", "Loseprazol", "Gaseka", "Omelika", "omeprazole".

Reviews

Reviews a makapisozi "Ortanol" olondola mokulirapo. Odwala kuti mankhwala othandiza antiulcer wothandizira. Mwamsanga kumatha kutentha ndi kumverera kwa kulemera ndi moto mmimba.

Akatswiri amanena kuti mankhwala funso kuli ndi ubwino pa njira ya matenda a thirakiti m'mimba pokhapokha ngati phwando ake wasankhidwa ndi gastroenterologist a. Madokotala amanena kuti zoti mankhwala ndikoletsedwa, monga kumakhudza amphamvu kwambiri.

Palinso mbali zabwino za mankhwala monga limapezeka ndi mtengo wotsika.