Homocysteine. Norma zinthu m'magazi

Homocysteine - dzina la asidi sulufule munali, kumene kumachitika m'thupi chifukwa cha processing wa methionine. The peculiarity wa nkhaniyi ndi kuti zifika kwa munthu kupyolera chakudya. Methionine lalikulu zedi opezeka nyama, mazira ndi mkaka. Ndi m'kati chimbudzi chakudya ndi thupi, aumbike ku methionine ndi homocysteine.

Ponseponse izi thunthu mu zikusintha pa moyo wa munthu. Ndi zaka, manambalawo pang'onopang'ono likutuluka. Isanafike isanayambike msinkhu kwa thunthu atsikana ndi anyamata homocysteine mlingo amene ponseponse 5 mol / L, pafupifupi chimodzimodzi. Pa msinkhu mlingo limatuluka 7 mmol / l, ndi achinyamata zikuchulukirachulukira kutchulidwa kuposa atsikana.

Ngati ife kulankhula za akulu, amuna homocysteine, amene ponseponse kuzungulira 10 mmol / L, apamwamba kwambiri kuposa akazi. The munthu wamkulu amakhala, ndi apamwamba mlingo wake asidi izi.

Pakati madona homocysteine mwina pang'ono m'munsi. Izi makamaka noticeable mu trimesters iwiri yoyambirira ya mimba. Pankhaniyi, musati mantha za ntchito zinthu homocysteine, Voterani akuchira atapita masiku 3 atabadwa. Pambuyo kuchepetsa mlingo asidi facilitates makope placental.

Nkhanizi wambirimbiri mu chamoyo ndi, akutivutitsa, yokutidwa ndi epithelium, makoma lamkati la mitsempha, chifukwa mu mipata anapanga. Kashiamu ndi mafuta, precipitating pamwamba zowonongeka, kulimbikitsa mapangidwe mipukutuyi sclerotic. Zimenezi zimabweretsa chakuti chotengeracho amakhala oletsedwa, kuchititsa thrombosis kapena chophukacho, kuchititsa sitiroko khateyo, ndi m'mapapo embolism kapena m'mnyewa wamtima infarction.

Anthu amene anakwezedwa mlingo homocysteine, pansi pa zikamera wa matenda a Alzheimer , ndipo ngakhale kukula kwa maganizo senile. Ndipo osakaniza shuga, zosokonezeka mtima amayambira (nephropathy, retinopathy, etc.).

Homocysteine akulangizidwa kuti aletse anthu onse ndi mbiri ya wolumikizira pano kapena thrombosis venous, matenda ischemic mtima. Ndipo akazi amene asunga matenda matenda, ndiponso amene achibale kuti matenda a mtima, sitiroko kapena thrombosis.

Zimathandiza kudziwa mlingo wa kusanthula homocysteine acid. Magazi zitsanzo zosankhidwazi ayenera kuchitidwa pa chopanda kanthu m'mimba (pambuyo chakudya ayenera kutenga maola osachepera asanu ndi atatu).

Kuwonjezeka ntchitoyo nkhaniyi mwina chifukwa zifukwa zingapo:

• Vitaminodefitsitnoe boma, makamaka ndi akusowa mavitamini B6, B1, ndi 12, ndipo folic acid.
• Kusuta ndipo kawirikawiri khofi (kanjedza achuluke ndi 3 mmol / l).
• Amangokhala moyo.
• Mowa.
• Mankhwala. Zimenezi zikugwira makamaka kukonzekera "MTX" - pakumwa folic acid antagonist (anawapatsa psoriasis), ndi mankhwala anticonvulsant (fetitoin - kumatha kupatsidwa folic acid mu chiwindi), nitrous okusayidi (ntchito mankhwala ochititsa dzanzi), metformin (shuga ndi polycystic n'kuwasanganiza syndrome) , aminophylline (ntchito matenda achikazi zochizira preeclampsia, limaleka zotsatira za vitamini B6) ndi kulera m'thupi.
• Aimpso insufficiency.
• Psoriasis.
• Khansa.
• Shuga.
• Hypothyroidism.
• Matenda pa mundawo m'mimba, kuchititsa malabsorption mavitamini.

Ife Moms kulera homocysteine zingachititse mavuto aakulu pa mimba: intrauterine kukula retardation, placental abruption, ndipo ngakhale yoopsa imfa. Hyperhomocysteinemia - waukulu chinthu n'zothandiza padera, kuwonjezera ana amabadwa ndi ubongo chubu zopindika ndipo clubfoot. pachifukwa chomwechi zingachititse osabereka mu akazi, imene implantation wa mwana wosabadwayo ndi kumakhala kovuta.

Kutsitsa homocysteine anati mu ofoola ziwalo.