Levonorgestrel: kodi ndi timadzi ichi, ndiponso umene ali ndi udindo mu thupi?

Anthu ambiri amadabwa kuti: levonorgestrel - kodi timadzi izi? Izi ndi progestagen kupanga kuti otembenuka endometrium minimizes ovulation inhibiting umuna oocyte anakonza. Komanso, akhoza mucosal zolandilira utachepa tilinazo analandira. M'nkhaniyi tiona kukonzekera munali timadzi otchedwa.

mankhwala

Mankhwala "Levonorgestrel" - ndi esitirojeni, amene kumathandiza kutsegula la umuna chifukwa kuwonjezera katundu ntchofu kukhuthala. Mankhwala amachita kwanuko mwa chiberekero mu mazira chubu, ndi endometrium, kugwirizana kwa ntchofu, chifukwa follicle-zolimbikitsa timadzi kumachepetsa ntchito zake.

Ingestion otchedwa mankhwala odzipereka mwachangu thirakiti m'mimba, Bioindication mpaka 100%. M'magazi, zigawo zake ndi anaikira pa pazipita phwando razovo 75 ml ya pambuyo 60 - 130 Mphindi. Ankaona timadzi interacts ndi madzi ndi globulin kumanga pafupifupi 50%.

Kagayidwe lolunjika pa chiwindi, kungokhala chete mawonekedwe pharmacologically metaboliks. The isoenzyme waukulu wa timadzi izi CYP3A4. Nthawi theka moyo zikhoza maola 30.

katundu

Poyankha funso "Levonorgestrel - kodi timadzi ichi?" ayenera kutsatira malangizo a dzina yemweyo mankhwala ndi malangizo a dokotala nawo. Indicators zambiri kusiyana kufunika kwa dongosolo la 1.0 ml ya / min. / Kg (madzi a m'magazi). timadzi litachotsedwa makamaka kudzera ureter ndi, gawo laling'ono atachotsedwa kathebuloyo.

Mankhwalawa zokhudza zonse zachilengedwe kugwa zizindikiro liwiro mu chiberekero ndi osapitirira 20 mg pa tsiku, ndipo patapita zaka zisanu kugwa 11. Mlingo pafupifupi linanena bungwe la timadzi imasiyana mozungulira 14 ug / 24 HR. Pa miyezi 50-60.

Intrauterine mankhwala analola kuti akazi ndi m'malo timadzi chithandizo molumikizana ndi esitirojeni, progestin si kuphatikizapo zikuchokera. Levonorgestrel - ndi amadzala timadzi mu madzi Mphindi 60 utsogoleli. Zolemba malire ndende m'menemo zalembedwa pambuyo pa masiku 14 ntchito.

umboni

Kugwiritsa ntchito mankhwala ndi zotheka ndi mankhwala intrauterine, komanso milandu zotsatirazi:

• Idiopathic menorrhagia lathu.
• Yaitali kulera zosiyanasiyanazi chitetezo.
• zodzitetezera pa kuchepetsa M'MALO ndi esitirojeni.
• Emergency mwadzidzidzi kulera.

The timadzi levonorgestrel, zotsatira za omwe ali ndi kuchuluka waukulu zotsatirazi zidzayenera ntchito pokhapokha umboni wa dokotala.

Ntchito ndi mlingo

Akuti mankhwala adamulowetsa jekeseni intrauterine - jekeseni wa uterine patsekeke. Ntchito masiku 4 kugonana kutachitika kuchuluka kwa mg wa 0,75 kwa 1.5. Emergency kulera akatswiri mwamphamvu analangiza kuti musamachite kuposa kamodzi pa miyezi isanu ndi umodzi.

Kuthetsa msambo, m'pofunika kutsatira mlingo analimbikitsa popanda kachiwiri ntchito. Musagwiritse ntchito malipoti mankhwala ndi mawu njira zolera okhazikika, monga izi amakwiya maonekedwe mavuto ndi amachepetsa mphamvu ya mankhwala. Pankhani ya uterine mapangidwe magazi pambuyo kulera mwadzidzidzi imene'yi analimbikitsa ndondomeko kufufuza ndi gynecologist, ndipo kuphwanya kusintha sabata zingapo zofunika kuzengereza chovomereza.

Only atakambirana ndi kuuzidwa zochita gynecologist milandu wamba, amalola nkhani ya mankhwala kwa kulera mu ana pa pangozi.

Monga timadzi levonorgestrel ntchito?

Kodi thupi ntchito timadzi anafotokoza, ndi chochita kupewa mavuto? Ndiye funso liukitsidwa ambiri. potsatira kwambiri katswiri malangizo, kulemekeza mlingo ndi malangizo - izo amatitsimikizira ntchito abwino mankhwala.

Pamaso ntchito, ndidzadutsa anayendera wa Navy gynecologist, kuphatikizapo cheke mammary zopangitsa, ziwalo m'chiuno, kupanga kuipitsa mbiri khomo lachiberekero.

Re bwinobwino ikuchitika pambuyo masiku 30-40 pambuyo unsembe wa mwauzimu, ndiye chaka, ndipo pamene pali presuppositions - zambiri. Izi mankhwala intrauterine othandiza kwa zaka 4 ndi 5. unsembe wake ayenera kuchitira yekha ndi dokotala okhazikika mu munda kapena kuti akudziwa ndi mtundu wa nkhani ya mankhwala.

kuopsa

Akazi kumwa mankhwala ndi progestogen, n'zotheka kuenjezera thrombosis venous mu nthawi yobvuta. Zizindikiro ngati pakufunikira kukhwimitsa mwamsanga matenda ndi mankhwala.

Pambuyo pa achire wa Navy wobereka resuscitated patapita miyezi isanu mu theka la azimayi amene ntchito patatha miyezi 12 - kuposa peresenti 96. lathu kulera zosiyanasiyanazi si zothandiza odwala ndi kunenepa.

contraindications

Anadabwa "Levonorgestrel - kodi timadzi ichi?" muyenera kuganizira contraindications onse. Pakati pawo:

• Beyond (Hyper) tilinazo, tromboflebitnye mapangidwe.
• Thromboembolism, kusintha mu mitsempha.
• Cerebrovascular matenda lathu, mimba.
• Ponena ingestion: matenda a chikasu ndiyo (kuphatikizapo mbiri), pathological zosokonezeka ya ndulu linanena bungwe kapena chiwindi, mkaka wa m'mawere.
• Kugonana kukhwima.
• Ndiponso, kwa IUD - mfundo urogenital matenda recurrences kapena yogwira kutupa mu mafupa a chiuno ndi, kumwa postpartum endometritis, pachimake matenda chiwindi.
• Septic abortifacient alowererepo pa trimester otsiriza, dysplastic kusintha uterine khomo pachibelekeropo kudwala mu magazi ofanana chiyambi wosadziwika, malignancies.
• Bwerani kapena anomalies kobadwa nako kupotoza fibroids.
• Progestagenoz (chotupa, kuphatikizapo zotupa chifuwa khansa).

zoletsa

Chinthu Kuchepetsa zambiri zogwirizana achire alowererepo mu chiberekero, malo ngati muli zizindikiro zotsatirazi kapena matenda aakulu:

• mutu kwambiri, wamba ndi makonsolo migraine ndi kusawona bwino, zizindikiro zina, lolunjika pa kuthekera kwa matenda mtsempha wamagazi;
• bwino wolumikizira oopsa malangizo, matenda a chikasu ndiyo, zovuta njira zowononga m'thupi, kuphatikizapo matenda a mtima ndi zikoti;
• shuga.

Muyenera yomweyo kufunsa kuthetsa wa Bulu nthawi mapangidwe kapena pamaso pa aliyense wa limati izi.

Mimba ndi mkaka wa m'mawere nthawi

Ngakhale mfundo yakuti levonorgestrel - ndi timadzi wamkazi, ntchito yake ndi zosavomerezeka pa mimba. Ngati iye anabwera, izo akulimbikitsidwa kuwonongedwa kwa dongosolo chifukwa chakuti kulera aliyense intrauterine kumaonjezera ngozi ya kubereka nthawi isanakwane komanso padera. Kuchititsa mayi dongosolo cholinga kapena kucotselatu nthawi zina zimabweretsa padera zikuchitika mosintha. Pamafunika malangizo katswiri pa kuthekera kwa kuchotsa yokumba mimba ngati n'zosatheka m'zigawo zolondola kulera.

Pamene n'zosatheka kuchotsa dongosolo intrauterine ndi kukhumba kofulumira kupulumutsa mimba wodwala ayenera kudziwa zingachitike ndi kuopsa kwa mwanayo chifukwa anabadwa msanga. Zikatero, muyenera kuwonetsetsa kuti aziona kwambiri mimba. Pamaso pa mtima ayenera kubweretsa mfundo zimene ziyenera yomweyo kudziwitsa za zizindikiro zonse, zimene zingakuthandizeni kuti afotokoze ndondomeko vuto.

mkaka wa m'mawere

Pamene Kuyamwitsa ndi ntchito "Levonorgestrel" za wina khumi mankhwala amalowa mwana thupi. Kuyamwitsa mkati chifukwa kulera mwadzidzidzi ayenera anasiya pa masiku 1.5.

Pakuti kachitidwe achire anaika mu utero, monga njira iliyonse progestogen-okha kulera zosiyanasiyanazi, ndi khalidwe limene ntchito miyezi theka pambuyo pa kubadwa alibe mavuto kukula ndi chitukuko cha mwana Chotero mankhwala sangayerekeze kuti angabweretse chiopsezo kwa mwana wosabadwayo pa mlingo analimbikitsa .

zizindikiro Kulanga

Ndi kubwerera ku funso "Levonorgestrel" - chimene icho chiri, "tiyeni tione zotsatira zotheka mbali ndi contraindications mankhwala Iwo angayambe machitidwe zosiyana za thupi ndipo zizindikiro zotsatirazi :.

1. Kuyambira wamanjenje dongosolo: kutopa, kuvutika maganizo, mutu, mmene alili.
2. GIT. Kusanza, kudzimbidwa, omangana, bloating.
3. Genito-mkodzo ziwalo. Magazi, kupatukana, ululu, candidiasis, Mwina mapangidwe zotupa zilonda ndi mtima wabwino.
4. Totupa, mawonetseredwe a chikanga, kuyabwa zidzolo, ziphuphu.
5. Other: kutupa, molumikizana mafupa, kuthamanga kukakhala, sepsis.

Nthawi zina khunyu a khunyu, kupotokola ndi kukomoka.

Limodzi ndi mankhwala ena

Kuphunzira "Levonorgestrel" (mtundu wa timadzi), m'pofunika kutchula kuthekera limodzi ndi mankhwala ena ozunguza bongo organic. Mu nkhani ya mankhwala mu funso inducers wa cytochrome P450 isoenzymes mwina ndichepe dzuwa chifukwa cha kuwonjezeka mu njira yake kagayidwe kachakudya.

The mankhwala otsatirawa akhoza kuchepetsa zotsatira za "Levonorgestrel":

• Gulu barbiturates, "Tretinoin", "carbamazepine" Nyimbo munali liziwawa St. John ndi komponatsiyu ake.
• Amachepetsa mphamvu ya anticoagulants, hypoglycemic, mankhwala anticonvulsant.
• "Levonorgestrel" kumawonjezera mphamvu glucocorticoids mu magazi, ndipo alinso amatha kusokoneza kagayidwe.
• Chifukwa yimitsira kugonana mankhwala recirculation, chifukwa ziŵalo zomera za m'mimba, kuchuluka magazi msambo kumachitika pamene zovuta kugwiritsa ntchito mankhwala ena.

Sangathe koma kuwonjezera, kulankhula za mmene mungagwiritsire ntchito "Levonorgestrel" kuti mankhwala zimenezi zimachititsa kumaonjezera mavuto a mankhwala ena, mankhwala kuti izo siziri. Pankhaniyi cha mankhwala osokoneza bongo amafuna mankhwala symptomatic.