Mankhwala 'Cefixime. malangizo

Kukonzekera "Cefixime" analogs (mwachitsanzo, medicament "Maksibat") ndi wachitatu m'badwo cephalosporin maantibayotiki ndi kanthu bactericidal (kukhoza kusokoneza kaphatikizidwe mu khoma selo mabakiteriya). Mankhwala bwanji aerobic ndi anaerobic tizilombo osiyana, monga galamu alibe ndi galamu HIV.

Bioavailability zikutanthauza ingestion la 45%. Mankhwala chimamanga zonsezo plasma mu peresenti sikisite. Excretion (excretion) ikuchitika ndi 50% ndi impso sichinasinthe. 10% excreted mu ya ndulu ya. mankhwala amasungidwa woipa mkulu mu mkodzo, ya ndulu ndi seramu kwa nthawi yaitali.

Mankhwala "Cefixime" mtsogoleri akuonetsa pa matenda chiyambi bakiteriya mu kapepala m'munsi ndi chapamwamba kupuma: chifuwa, zilonda zapakhosi, sinusitis, pharyngitis. Mankhwala akusonyeza kuti pathologies opatsirana biliary thirakiti, zimakhala zofewa, dongosolo mkodzo, khungu, ndi otitis, wopepuka chinzonono mu chiberekero ndi mkodzo, endometritis, osteomyelitis ndi matenda ena okhudzana ndi ntchito tizilombo atengeke.

Medicine "Cefixime" malangizo imaletsa Kusankhidwa kwa ana osaposa miyezi isanu ndi umodzi, pakati ndi lactating odwala, odwala hypersensitivity kwa zigawo zikuluzikulu. Makamaka kusamala anasonyeza pamene akumwabe mankhwala okalamba, pamaso pa matenda a m'matumbo (mu mbiri komanso).

Amatanthauza "Cefixime" malangizo Buku amalimbikitsa kutenga mkati. Mlingo tsiku la mankhwala kwa odwala ndi zaka khumi ndi ziwiri (ndi thupi la makilogalamu oposa makumi asanu) - mamiligalamu mazana anai kamodzi pa tsiku, kapena mamiligalamu mazana awiri kawiri pa tsiku.

Pamene unyinji wa wodwalayo zosakwana anati mankhwala akuchipatala pa mlingo wa mamiligalamu atatu ndi inayi pa kilogalamu. Kenako, mlingo akhoza ziwonjezeke kwa 12 mg / kg.

Kutalika kwa mankhwala "Cefixime" avareji masiku asanu kapena khumi.

Kuthetsa wopepuka matenda a chinzonono khomo pachibelekeropo ndi mkodzo anaika anayi milligram mlingo.

Ana kwa zaka khumi ndi ziwiri Kwalamulidwa mankhwala mawonekedwe inaimitsidwa. Mlingo wa mankhwala "Cefixime" mtsogoleri akuonetsa kuti kukhazikitsa zotsatirazi: mpaka chaka - 2.5-4 ml, awiri kwa zaka zinayi - 5 ml, kuchokera zisanu ndi zaka khumi - 6-10 ml. Mankhwala mawola khumi ndi ziwiri.

Pakuti yokonza suspensions ayenera zidzawonjezedwa kwa mbale ndi ufa Cincino Botolo la madzi otentha (kaŵiri) ndi kugwedeza mpaka yunifolomu (homogeneous) kusakaniza. Ndiye kuyimitsidwa analoledwa kuima kwa mphindi zisanu. Patsogolo ntchito mankhwala mbale ayenera zidzagwedezeka.

Zotsatira ambiri osafunika pamene mukumwa mankhwala "Cefixime" malangizo ndi kulira m'makutu, malungo, kuyabwa, kufupika kwa mpweya, ankatenthetsa khungu, ming'oma, chizungulire, eosinophilia, leukopenia. Nthawi zina, pakhoza kukhala thrombocytopenia, neutropenia, Chotupa chija, hemolytic magazi m'thupi, candidiasis. Mwa mavuto tisaiwale nseru, mutu, m'mimba, stomatitis, hypovitaminosis B. Medicine "Cefixime" zingachititse interstitial nephritis, kusanza, pseudomembranous matenda a m'matumbo.

Odwala ndi mbiri imene pali umboni wa thupi lawo siligwirizana ndi penicillin mwina kusonyeza kuchuluka kudziwa mankhwala ija tsefaplosporinovogo. M'kati mwa mankhwala akhoza kukhala wabodza zabwino mwachindunji Coombs 'mayeso ndi mkodzo shuga.

Pamaso chithandizo ndikofunikira kugwira ndi mayesero zonse zofunikira kuyezedwa. Musanagwiritse ntchito mankhwala "Cefixime" awerenge malangizo ntchito.