Yafupika monocytes - ndi harbingers matenda

Monocytes - mtundu wa leukocytes lalikulu yogwira phagocytic maselo a magazi, amene kwaiye mu m'mafupa. masiku 2-3 ataloŵa otaya magazi monocytes zazikulu zili zimakhala ndi kusintha mu macrophages. Ntchito yaikulu ya macrophages monocyte-linachokera ndi kuyamwa wothandizila yachilendo - mankhwala, mapuloteni, maselo umodzi. Choncho monocytes kuyamba yeniyeni yankho zimakumana ankhondowo antigens yachilendo. A kuwonjezeka kwambiri a antigens zingakubweretsereni monocytes kuwongolera, ndi zina kukula mofulumira.

Norma monocytes magazi

Kuchuluka kwa monocytes m'magazi - kuchokera 1 mpaka 8 peresenti. Tsimikizani ndi kuchuluka kwawo pamene unachitikira malamulowa. Monocytes ndi adatchithisira tikadwala mankhwala, "Prednisolone" ndi ofanana. Chiwerengero cha monocytes kuti phagocytes ena anatsimikiza ndi kuswana leukocyte. Yafupika monocytes amakonda chifukwa ponso maselo oyera, pamene pachilichonse za phagocytes nthawi zambiri unkagwiritsidwa ubwenzi wawo.

Phagocytic maselo magazi mtima kumatanthauza matenda matenda. Pa mankhwala ndi mankhwala amphamvu yafupika monocytes zikhoza adamulowetsa ndipo anapambana nkhondo maselo mlendo. The bwino pamaso pa leukocytes ndi monocytes m'magazi kumawonjezera mphamvu ya mankhwala.

maselo oyera ndi adatchithisira, monocytes kuchuluka

njira Pathological mu thupi, ngakhale waung'ono kwambiri kupangitsa ponso monocytes - monocytosis.

Wachibale monocytosis zambiri limodzi ndi kuchepa kwambiri woyera achiyesa maselo a magazi, ndi khalidwe la neutropenia kapena lymphocytopenia. Yafupika monocytes, monga ulamuliro, musati chifukwa mantha pamene monocytosis ndi chizindikiro cha matenda otsatirawa:

• aakulu myelomonocytic khansa kapena monocytic;
• myeloblastic khansa, pachimake monoblastic khansa, matenda Hodgkin ndi;
• infective endocarditis, rickettsial ndi protozoal, tizilombo;
• lupus, nyamakazi, polyarteritis;
• brucellosis, anam'peza matenda a m'matumbo, enteritis, chindoko.

Mlingo wochepa wa leukocyte

Yafupika woyera achiyesa maselo a magazi amatchedwa leukopenia. matenda bwino zimayamba ndi:

• mafupa umabala maselo oyera zedi osakwanira;
• chiwonongeko cha leukocytes mwachindunji mu zotengera mwazi;
• Stagnation wa leukocytes ndi kuchedwa mwina zofikira matupi;
• neutralization wa leukocytes m'zochitika mphamvu-majeure (by kugwa kapena mantha).

Zinthu zokhudza mapangidwe leukocytes

M'mavuto mapangidwe mankhwala osiyanasiyana leukocyte yotupa, monga "Phenylbutazone" "Amidopyrine", "Analgin" ndi "pirabutol". leukopenia komanso amathandiza kuti chitukuko cha mankhwala a kanthu antibacterial, "levomitsitin", "sintomitsina", "sulfanilamide". Kuchepetsa mlingo wa leukocytes mu magazi cytostatic wothandizira-methotrexate, ndi cyclophosphamide.

Ntchito yaikulu ya macrophages minofu, monocytes, maselo oyera ndi anthu ena ndi mayamwidwe particles zoipa kuti pena anaonekera mu thupi. Izi zimachitika achilendo kuyeretsedwa magazi m'kati phagocytosis, mmene udindo dominiruschaya monocytes akapatsidwa ngati maselo waukulu phagocytic.

Monocytes amakonda tsitoskopicheskoe zimakhudzanso maselo a khansa ndiponso tizilombo toyambitsa matenda a malungo. The chifukwa kusanthula "yafupika monocytes" kumatanthauza kuti thupi lawo n'chochepa kuposa chiyenera kukhalira, koma chifukwa sakhala ogwira, koma ntchito zawo ikutsatiridwa.