"Atorvastatin": ndemanga, analogs, zikuchokera ndi malangizo ntchito

Mankhwala ambiri cholinga kuchepetsa kuchuluka kwa okwana mafuta ndi LDL ndi "Atorvastatin". Umboni za izo osokoneza, ngakhale khalidwe la mankhwala zikutsimikiziridwa ndi maphunziro matenda. Pa nthawi yomweyo mankhwala ali chimodzi chokha zonse kunachitika mpikisano - "Rosuvastatin" (ndi generics ake). Chifukwa zimaonetseratu kuti "atorvastatin" kukonzekera mtima umboni chisathe mudziwe cholinga. Choncho, kupenda zotsatira zake chofunika kusanthula bwinobwino za njira ya kanthu ndi chakudya cha malangizo Ufumuyo ntchito.

Zokhudza zonse mankhwala mankhwala mapangidwe

Atorvastatin wa kalasi pharmacological m'badwo statins lachitatu. Ndi inhibiting enzyme udindo kaphatikizidwe amkati wa mafuta m'thupi, amachepetsa chiwerengero cha atherogenic lipoprotein nusu. Low-kachulukidwe kachigawo (LDL) umathandiza mafunsidwe a mafuta ndi chifukwa mayankho m'thupi mwa endothelium chifukwa cha zimene zolengeza osauka.

Ngati statins zina, atorvastatin kwambiri kuchepetsa kuchuluka kwa LDL, choncho kwambiri kubweza kukula kwa zolengeza. Mu khalidwe limeneli kwa involution ake si mwaona ndi awiri a mtsempha wamagazi ndi inatsekeratu (kapena atherosclerotic ina), akanali yemweyo. Zotsatira matenda - liwiro chitukuko cha matenda a mitima, cerebrovascular kapena aakulu wolumikizira insufficiency wa miyendo m'munsi.

"Atorvastatin": zikuonetsa ntchito

Tisanayambe chofunika chimatanthauza zikuonetsa ntchito mankhwala. Iwo anachokera ku limagwirira zofunika kanthu ndi imakhudzana ndi mafuta-kutsitsa kwenikweni. Osiyanasiyana zikuonetsa:

• kumtundu (banja) hypercholesterolemia, heterozygous;
• polygenic (chachikulu) IIa hypercholesterolemia kalasi malinga Fredrickson;
• Kuphatikiza (IIb) dyslipidemia;
• Homozygous banja hypercholesterolemia;
• hypertriglyceridemia (chithandizo ndi statin osakaniza zakudya ndi zinthu zolimbitsa thupi);
• zinthu kugwirizana ndi zotupa atherosclerotic mtima wa mtima khoma, ubongo, impso, m'makona;
• oopsa ndi mkulu chiopsezo mtima;
• kupewa zochitika pachimake inatsekeratu ndi maziko a zotupa wogwila atherosclerotic ya mitsempha inatsekeratu;
• kupewa m'mnyewa wamtima infarction kukonzanso kapena kachigawo ubongo.

kuwerenga kudziwa milandu pamene chofunika poika "Atorvastatin" mankhwala. Madokotala za tanthauzo lake momveka bwino kutsimikizira zimenezi. Ndi choona chotsimikiziridwa kuti statins, kuphatikizapo "Atorvastatin" ndi generics ake ambiri ndi owopsa kardioform acetylsalicylic asidi, ngakhale chimodzimodzi amathandiza kuchepetsa mosavuta kukhala woyamba m'mnyewa wamtima infarction ndi kubwereza milandu.

analogues mankhwala

magome onse "Atorvastatin" imene ndemanga angathe kuwerenga pansipa, opangidwa ndi makampani osiyanasiyana mankhwala. Nthawi zambiri mayina a mankhwala kusinthidwa, amene amalola iwo okhala. maina Trade analogues, ndiye mankhwala okhala atorvastatin monga mbali yogwira otsatirawa: "Anvistat" ndi "Atokord", "Atomas" ndi "Ator", "Atorvoks" ndi "Atoris", "Vazotor" ndi "Lipoford" "Lipitor" ndi "Liptonorm", "Novostat" ndi "Torvazin", "Torvakard" ndi "Tulip".

Komanso, ena opanga kubala mankhwala awo "Atorvastatin" (mukhoza kuwerenga ndemanga pansipa) pansi pa dzina malonda yemweyo. "Actavis", "Vertex", "Izvarino Pharma", "ALSI Pharma", "Canon Pharma" Obolentsenskoe kampani mankhwala, "Protek-SVM", "North Star", TABUK asatayike, TEVA mankhwala Makampani, ndi ena apange dzina mankhwala chomwe ndi alendo ( "atorvastatin") ndi kuwatonthoza chikhalidwe. Chitsanzo "Atorvastatin Teva", ndemanga zimene zimatsimikizira nchito zake matenda.

kapangidwe

Mayina mankhwala 'atorvastatin malangizo ntchito, ndemanga ndi malangizo kuchipatala mulibe nkhani kusiyana mitundu mlingo. Zochita kusiyana maganizo ilipodi, ndipo zonse mphamvu ya kanthu achire. Cofunika n'cakuti mmene mwamsanga zotsatira akangofika mlingo. N'chifukwa chake akuti "Lipitor" ndi Buku la mankhwala pachiyambi.

Mlingo mawonekedwe limapangidwa atorvastatin mapiritsi kashiamu ndi chipolopolo. Otsiriza, nayenso, imakhala kashiamu carbonate, microcrystalline mapadi, lactose monohydrate, polysorbate 80, sodium croscarmellose, magnesium stearate, hydroxypropylcellulose, talc, titaniyamu dioxide, polyethylene glycol, hydroxypropylcellulose, simetikonovoy emulsion, benzoic asidi ndi asidi sorbic.

Mayina choyambirira Buku mankhwala "Atorvastatin" malangizo (ndemanga pa mfundo iyi) lilibe mfundo za kulemera kwa aliyense zikuluzikulu. Ichi ndi chinsisi malonda a kampani American PFIZER HCP CORPORATION. Chotero mlingo mawonekedwe "Lipitor" amatilola kukwaniritsa ndende zonse atorvastatin m'magazi.

Tikaphatikiza mawonekedwe "atorvastatin"

Pokonzekera "Atorvastatin" mtengo (umboni mtima titsimikizire kuti) ofikika osiyanasiyana odwala. Ndi mankhwala wosavuta kuti angathe pamodzi ndi makalasi zina za mankhwala. Nthawi zambiri, "atorvastatin" ndi statins ena amapangidwa kwayekha, ndiko piritsi limodzi ndi chimodzi chokha yogwira pophika. Komabe, pali njira kuphatikiza.

Zitsanzo za mankhwala awa: "Kaduet", "Duplekor", "statins". Pano, "atorvastatin" ali pamodzi amlodipine, kashiamu njira blocker, amene amagwiritsidwanso mankhwalawa matenda mtima. Mlingo wa mankhwala amasankhidwa dokotala.

Standard mlingo "atorvastatin"

Mankhwala "Atorvastatin", zizindikiro, maumboni ndi malangizo pa ntchito yachipatala imene tikambirana taphunzira, lilipo Mlingo atatu muyezo: 10, 40 ndi 20 mg. A ophatikizana kukonzekera "Kaduet" lili 10 mg wa atorvastatin ndi amlodipine 5. "Statins" amapangidwa m'njira ziwiri: 10/5 ndi 10 / 10mg. Pokonzekera "Duplekor" 4 mlingo wa atorvastatin ndi amlodipine: 10/5, 10/10, 20/5, 20/10 mg. Izi amachepetsa chiwerengero cha mapiritsi odwala amene ali ndi ntchito ndi statins ndi blockers kashiamu njira zochizira matenda. Izi zimatheka ndi kuchepa mu mtengo wa chithandizo.

Kusankha wapadera "atorvastatin"

Choyamba njira kupanga atorvastatin wagwidwa kugulitsa ndi "Lipitor". Izi ndi mankhwala loyambirira, lomwe ikuchitika mayesero. Kenako panali mankhwala ena pansi mayina ena. Kuti kalembera chofunika chokha chitsimikiziro mwamwambo chabe bioequivalence "Lipitor." Pa nthawi, zikhoza popitilira ndi opanga ochepa. Choncho, kupeza dotolo dokotala kwa mankhwala alipo "Atorvastatin" analogues wa ndemanga izi ayenera kuphunzira mosamala.

Nthawi zambiri, dokotala akuonetsa mankhwala watsimikizira bioequivalence "Lipitor" ndi chiyani ndi mmene zafotokozedwa mu malangizo Ufumuyo. Mtengo wa "Lipitor" zilipo, n'kosavuta kuti tikhale nacho zambiri zosangalatsa. Komabe, si Kwalamulidwa kwa odwala ndi maofesi wogwila chifukwa chilema matenda. Pankhaniyi, anthu mankhwala kuti mwina mankhwala concessional olamulidwa ndi Center pamayeso ndi mayesero mankhwala. mogwira lawo linali.

Umboni za "atorvastatin"

Pa yokonza "Atorvastatin" review wodwala aliyense sangakhale woyenera, chifukwa popanda potaya zamadzimadzi mbiri sizingatheke kuweruza zotsatira za mankhwala. Choncho, pofuna kuonetsetsa dzuwa, izo asanthule kusintha kwa tuzigawo twa zamadzimadzi. Komanso "Atorvastatin", ndemanga zimene zilipo lalikulu zedi, amene amapereka malangizo pa zochita chowawa. Ambiri matupi awo sagwirizana ndi zotsatira. Kawopsedwe ndi otsika ndi zambiri imperceptible. Komabe, mu Mulimonsemo maonekedwe a syndrome cytolysis ndi transaminases kuwonjezeka zitatu amafuna kuchotsa mankhwala.

Odwala kuti zotsatira poizoni n'zochepa. Chifukwa cha ichi, anthu odwala ambiri akulangizidwa anzawo mankhwala kapena achibale, ngakhale kopita chofunika wazachipatala, kuwerengetsa zowopseza ndi mtima wa tuzigawo twa a lipids magazi. Komanso, ambiri mankhwala yopanda anatumizidwa katundu, mwachitsanzo, kuti angathe kuchepetsa thupi.

Koma tione kufunika kukhala ndi "Atorvastatin" ndemanga mankhwala. Slimming si yabwino, ndipo akhoza kutumikiridwa molumikizana ndi katundu ndi zakudya. Tikaphatikiza ntchito "atorvastatin" ndi zina wothandizila zamadzimadzi-kutsitsa, monga kawirikawiri analimbikitsa anthu popanda kuphunzira zachipatala, kumabweretsa rhabdomyolysis ndi chiwindi kawopsedwe.

Reviews madokotala za mankhwala

Pa yokonza "Atorvastatin" review dokotala n'kofunika kwambiri kuposa review wodwalayo. N'chimodzimodzinso ndi mankhwala ena. Ambiri, ndemanga abstracts onse akatswiri zimaonetsa chitetezo mankhwala ndi mogwira mtima. Amachepetsa okwana mafuta ndi LDL, pamene kuwonjezeka HDL. Izi ndi zofunika kwambiri chifukwa zimathandiza kuti azikula ya zolengeza atherosclerotic, ndipo sachedwa isanayambike infarction m'mnyewa wamtima.

Mphamvu hypocholesterolemic zotsatira pokonza "Atorvastatin" (a review wa pafupifupi aliyense dokotala kutsimikizira izo) ndi zimasonyeza kwambiri. Normalization wa mbiri seramu zamadzimadzi zimatheka m'miyezi 1.5-2. The "rosuvastatin" zimatheka mwa masiku 30-50. Komabe, pamene "atorvastatin" zambiri maphunziro kuchipatala wotsimikizira nchito zake ndi chitetezo. Ambiri, izi ndi awiri wabwino mankhwala, omwe mwina ntchito zochizira hypercholesterolemia ndi prophylaxis matenda mtima.

Mtengo wa mankhwala

Mankhwala "Atorvastatin" mtengo (ndemanga zambiri za svidelstvo izi) osiyanasiyana malingana ndi Mlengi. Zodula kwambiri ndi "Lipitor" - mankhwala pachiyambi. Mwezi chithandizo mtengo ndi 900-1100 rubles pamene kulandira mlingo wa 40 mg. Pa mlingo tsiku la mtengo chithandizo 20 mg wa ndi 800-900 rubles. Angaperekedwe "Lipitor" ndi mtengo kwambiri.

Mtengo wa chithandizo ndi mwezi "Atoris 40 mg wa" rubles 500, pamene kulandira 20 mg - 200 rubles. The "Atoris" - ndi bioequivalent "Lipitor" mankhwala, kwathunthu n'kubweretsa. Palinso mtengo mankhwala, "Torvakard" "Lipitor", "Torvas" mtengo wa chithandizo pamwezi mu mlingo tsiku la 40 mg wa ku rubles 300 mtengo. Ndi mtengo wa mankhwala ndi mlingo tsiku la 20 mg wa adzakhala 100-150 rubles.