Zifukwa zimene akhoza wokwezeka pa basophils wamkulu

Basophils ndi granulocytes lalikulu kwambiri, lomwe anapanga mu m'mafupa kenako mu magazi. basophils magazi zimafala kwa maola angapo. Kenako, kudutsa mu zimakhala, kumene moyo wawo amayembekezeka ndi za 8-12 masiku.

Basophils ndi kagulu ka leukocytes kwambiri. Chotero ngati basophils kuchuluka akuluakulu, nthawi zambiri anafotokoza za njira ya matenda aliwonse mu thupi. Pofuna kudziwa bwino zimene anali chifukwa cha kuchuluka kwa basophils m'magazi, tiyenera adzanyamula kukumbukira kuti iwo achite mu thupi ntchito zambiri zofunika. Mwachitsanzo, basophils anakhalabe mu zotengera yaing'ono ya magazi, kupereka njira kusamuka kwa leukocytes ena, komanso zimakhudzanso othandiza pa kukula kwa capillaries latsopano. Pa nthawi yomweyo, ali nawo thupi lawo siligwirizana ndi yotupa selo. Limagwirira kanthu mu nkhani iyi ndi: basophils, pamene iwo zimakhala ndi mtima maselo mafuta munali histamine, womwe ndi yogwira kwachilengedwenso mankhwala kumene kumapangitsa chiwonetsero cha ziwengo. Ndiko kuti, pamene basophil ndi allergen ndi zikachitika, kumachitika degranulation: granules zomwe zili mkati adzaonongedwa, chifukwa mu zigawo biologically yogwira kulowa magazi. Ndi kuyamika basophils poizoni analowa m'thupi kudzera nsikidzi wa tizilombo, izo yomweyo choletsedwa mu zimakhala ndi sikuti kudzalamulira thupi. Komanso, basophils zikuchokera zikuphatikizapo mchitidwe monga heparin. Atatero, lamulo la coagulation magazi ikuchitika.

Basophils angathe phagocytosis ndi chemotaxis, koma alibe phindu kwenikweni chitetezo cha thupi. Ichi ndi chifukwa amanena otsika. Popeza chiwerengero cha basophils ali wamkulu ayenera 0.5-1% ya leukocytes onse. Ngati basophils pamwamba chilengedwe, chikhalidwe wotchedwa basophils. Zochita matenda, kumachitika kawirikawiri. Zina mwa zifukwa zimene basophils akhoza wokwezeka pa wamkulu, n'kopanda zotsatirazi zinthu pathological ndi matenda:

• anam'peza matenda a m'matumbo, aakulu yotupa matenda a thirakiti matumbo;
• aakulu sinusitis;
• matenda magazi: lifogranulemotoz, aakulu myeloid khansa, pachimake khansa, polycythemia vera;
• myxedema;
• matenda Hodgkin ndi;
• hemolytic magazi m'thupi;
• thupi lawo siligwirizana;
• shuga;
• m'mapapo khansara;
• ndi vuto losowa vitamini B12;
• pox;
• kulandira mankhwala odana chithokomiro ndi esitirojeni.

N'zochititsa chidwi kuti adziwe kuti iwo akhoza osati kuchuluka basophils mu wamkulu, komanso adatchithisira. Kuchepa basophils magazi otchedwa bazopeniey. Iwo ulibe phindu matenda izo lingachititse:

• pachimake matenda osiyanasiyana;
• nkhawa;
• hyperthyroidism;
• matenda Cushing ndi;
• ntchito corticosteroids.

Akazi ayenera kudziwa kuti pangakhale basophils magazi anakweza kapena kumuika nthawi ovulation, pa chiyambi cha kuzungulira kusamba ndi pa mimba. Ngati zinthu zimenezi chifukwa kuwonjezereka kapena kuchepa zili basophils, palibe chifukwa nkhawa, ndiye iwo adzakhalanso ndi mlingo chofunika.

Ngati basophils inachuluka wamkulu chifukwa ntchito iliyonse ya mankhwala, iwo ayenera anasiya pomwepo. Ngati chifukwa ndi akusowa vitamini B12, m'pofunika kuti chifukwa chosowa izo. Izi zikhoza kuchitika mwa kudya zakudya monga nyama, mazira, chiwindi, mkaka, cheese. Ngati chifukwa lagona pa matenda ena, n'kofunika kuti dokotala mankhwala mankhwala. Pamene matenda ndi kuonedwa, basophils ndi dekhetsa.