APTT lakuti: N'chifukwa chiyani zimenezi? Kuonjezera APTT pa mimba

APTT (adamulowetsa tsankho thromboplastin nthawi) - uyu ndi chizindikiro yofunika kwambiri clotting magazi, amene amalola kudziwa chiopsezo cha magazi kuundana kapena pakutchulidwa magazi. Molondola poona ntchito za dongosolo coagulation, mukhoza kuona aakulu matenda ndi, ndi kusankha mankhwala molondola. Tiyeni tikambirane.

Kodi APTT mayeso?

Ri pa mlingo wa clotting magazi Zimathandizanso kudziwa kuvutika zokhudza zonse zimene zambiri amasonyeza kuti pali kuyan'anila za kachulukidwe ndi zizindikiro Mkhalidwe wa magazi.

Chotero kusanthula ndi ikuchitika chitsanzo yeniyeni. Choyamba, nkhani kuyezedwa akuwonjezeka chubu munali anticoagulant ankameteramo ubweya wa ayoni calcium, chifukwa magazi a sakutero aumirira. Zagwiridwa ndi centrifugation kupatutsa madzi a m'magazi ku maselo othandiza magazi kuundana ndi zinthu zina. Kenako, mayeso chubu Chinawonjezeka phospholipids, kashiamu kolorayidi ndi activator. Kuyambira kuwunika nthawi imene magazi aumirira aumbike.

Phospholipids yambitsa njira extrinsic ya coagulation, ndi calcium mankhwala enaake ndi chinthu chofunika mu ndondomeko ya coagulation. kusanthula zimenezi si kwathunthu amayang'anitsitsa ndondomeko ya thrombus mapangidwe, koma zimathandizanso kudziwa kuvutika mu mlingo, ndiye yang'anani kwa zimayambitsa zodabwitsazi.

Nthawi zina likukhalira kuti APTT kuchuluka kapena utachepa. Zimenezi zikusonyeza mavuto alipo mu thupi.

wakudziko

Chizindikiro anayeza masekondi ndi siyana chifukwa mphamvu, m'badwo wa wodwalayo komanso chithandizo. APTT Normal wamkulu anthu ndi kwa masekondi 28 mpaka 40. Pa ana akhanda, chithunzi ichi ndi apamwamba masekondi 1-3.

Okwera magazi aPTT amawapeza pamene aliyense clotting chinthu yafupika kapena chinawonjezeka ndi anthu oposa 30%. Yafupika mlingo zambiri limasonyeza hypercoagulability.

Khama la APTT akuluakulu ndi ana umachitika kudziwa chifukwa cha kuundana osauka magazi, komanso kuti asa- mphamvu ya mankhwala ndi anticoagulants.

Zifukwa kuwonjezeka APTT

Ambiri wokwiya kwambiri pamene iwo tikupeza kuti APTT kuchuluka. Kodi zikutanthauza chiyani? Izi zimachitika pamene pali chiopsezo magazi. Zifukwa zingakhale:

1. Osakwanira kuchuluka kwa vitamini K mu thupi. Zimenezi zikusonyeza mavuto dongosolo m'mimba, chifukwa vitamini imeneyi amalimbikitsa kaphatikizidwe mabakiteriya matumbo. Komanso n'kofunika kwambiri kuti uziyenda yachibadwa zinthu zonse clotting. akusowa ake kumachitika chifukwa dysbiosis, ndi zakudya ndi mwamakani, chifukwa mankhwala yaitali ndi mankhwala.
2. Majini kuvutika kuti imakhudzana ndi kuphwanya magawo Mkhalidwe ndi kachulukidwe magazi. Pankhaniyi, index APTT kwambiri.
3. Postpartum kukha mwazi pachimake khansa, DIC.
4. Amapatsira mwana wake mtundu A, B, C.
5. Kukhalapo kwa chitetezo mu magazi ndi zinthu kungomanga ndi lupus anticoagulant.
6. Kusagwiritsa pokonzekera kusanthula ndi ingress mwangozi heparin mu chitsanzo.

Kuchuluka APTT, mwana akhoza kukhala chifukwa zifukwa izi.

APTT pa mimba

Woyembekezera, ndi adamulowetsa tsankho thromboplastin nthawi wayamba kusintha. Ngati kugunda kwa anthu ambiri pakati pa masekondi 28 mpaka 40, mu akazi apakati ndi masekondi 17-20. Izi zikutanthauza kuti yafupika. asinthire zoyambitsa zinthu zotsatirazi:

• Mu yovuta imeneyi mu thupi la mkazi, ndi zina utero-placental kufalitsidwa. Latuluka imakhala ndi kuchuluka kwa ziwiya. Ngakhale pamafunika ayike detachment yaing'ono, kutaya magazi kungakhale kwambiri. Kawirikawiri detachment kumachitika chifukwa kuchuluka uterine kamvekedwe.
• Nthawi yobereka mkazi zambiri wotaya mpaka 400 ml ya magazi. Izi zimachitika mofulumira kwambiri, ndipo dongosolo coagulation ayenera kukhala okonzeka imfa yoteroyo choopsa cha mwazi, kuundana amagwiritsidwa wayamba mwachangu kuteteza zina magazi otayika.

Chifukwa APTT kukwezeka mimba?

APTT kwambiri chifukwa ngati nthawi clotting ndi masekondi oposa 40. Izi amachepetsa mphamvu ya magazi kuundana kupanga, chifukwa mu chiopsezo cha imfa magazi.

Bwinobwino APTT kuchuluka ngati mayi woyembekezera ndi kutenga mankhwala, heparin, aspirin ndi mankhwala thrombolytic. Pamaso ayesedwe, tiyenera awadziwitse dokotala awo.

Kuwonjezeka APTT limasonyeza kuchepa mphamvu magazi kuti aumirira, ndipo zimachitikadi otsatirawa zinthu pathological:

• chiwindi matenda atavala anasonyeza kwa chiwindi kulephera, kuphatikizapo ndi matenda enaake. Pankhaniyi pali kuphwanya kaphatikizidwe zinthu clotting m'magazi.
• Losowa vitamini a K, amapezeka ndi maziko a dysbiosis m'matumbo, komanso chifukwa zakudya zosayenera.
• Khansa.
• Amapatsira mwana wake mtundu A, B, C. Iyi ndi matenda otengera yodziwika ndi akusowa kobadwa nako zinthu clotting nthawi zambiri zimayambitsa magazi mowiriza zimachitika.
• matenda Von Willebrand a.

Pomaliza

Analysis pa APTT kwenikweni umachitikira pamaso ntchito adzaimira kupeza momwe kudya magazi akhoza aumirira. Ponso kapena kuchepa mwakale limasonyeza pathologies zosiyanasiyana. Kupewa kufala kwa magazi, kuchitira mogwirizana.