Pseudomonas aeruginosa: mankhwala makamaka

Pseudomonas aeruginosa kapena Pseudomonas aeruginosa - makina galamu amatanthauza osiyanasiyana. Mu chikhalidwe, kunafalikira, izo amakhala ku nthaka ndi madzi, zomera, mu kapepala m'mimba mwa nyama ndi anthu. Mwina avundulidwe ambiri yaying'ono-chamoyo kuti zingaoneke mu zitsanzo za madzi anatengedwa ku zinthu zachilengedwe.

Kodi osiyana ndi ena mabakiteriya osiyanasiyana, chifukwa chidwi kwambiri madotolo ndi asayansi anakopeka Pseudomonas aeruginosa? Chithandizo njira pathological chifukwa cha bakiteriya ichi, n'kovuta kwambiri, ndi Wand ndi multiresistant opha tizilombo. Pamodzi ndi Mycobacterium TB ndi tizilombo ta ena a staphylococci, adzaupereka kwa mabakiteriya amalimbana kwambiri chemotherapeutic mankhwala alipo lero. Koma ngakhale pa mndandanda, pamafunika malo kutsogolera.

Ichi ndi chifukwa kukhalapo kwa biofilm, amene ali ndi udindo woteteza, komanso chotchinga amene analengedwa ndi akunja lipopolysaccharide Kakhungu. Ndipo pali mitundu amene ali kugonjetsedwa ndi mankhwala pafupifupi onse masiku ano.

Komabe, Pseudomonas aeruginosa, kukonzekera mankhwala amene kumakhala kovuta, tcheru phenol (2% njira), 3% hydrogen peroxide ndi chloramine (0.5% njira). Mu chilengedwe, makamaka mu madzi ndi mpweya chinyezi, bakiteriya amatha osati apitiriza yaitali, komanso zikuchulukirachulukira. Mulingo woyenera chitukuko akuti ndi 37 ° C kutentha, komanso pa 42 ° C Bacillus angathe kukula.

Pseudomonas aeruginosa: Zizindikiro

A mbali yofunika kwambiri mu kukula kwa bakiteriya matenda nosocomial, chiopsezo ku mawu a matenda ndi limalephera, zimbuzi Muzikonza mipope amangomvera, zinthu yonyowa (mathawulo, mwachitsanzo). zotupa Local amayambira pa malo amayaka ndipo seams postoperative, mabala ndi zilonda. Nthawi zambiri ndodo ndi otitis, pyoderma, dermatitis. Chifukwa cha kuvulala kapena opaleshoni bakiteriya zingachititse matenda a maso, komanso kapepala mkodzo (zambiri ntchito catheter).

Pakuti njira yaikulu yotupa, sipangakhalenso zikuchititsa kuti Pseudomonas aeruginosa, monga endocarditis (kuwonongeka kuli nthambi mtima), chibayo, ubongo abscess, kakhosi, matenda mantha, zimfundo. Ambiri matenda kwanuko chifukwa ndodo iyi, nthawi zambiri kumayambitsa bacteremia - matenda a thupi lonse mogwirizana ndi malowedwe a nthumwi opatsirana m'magazi.

A khalidwe mbali ya izi bakiteriya ndi amphamvu kusankha endo- ndi exotoxins, hemolysin, cytotoxins, mkulu proteolytic ntchito, kaphatikizidwe hyaluronidase, luso kuti lithe krahmalopodobnogo pawiri monga ntchofu, amene ukuwonjezeka zomatira katundu, komanso nambala ya inki. Zotupa chifukwa cha anati bakiteriya zimachitika matenda kuledzera, mkulu kutentha. Makamaka, Pseudomonas chibayo etiology nthawi akuthamanga molimbika, penyani m'mawa nsonga ya malungo, kufupika kwa mpweya ndi cyanosis. Mkulu amafa (50-60%) unkachitika pa bongo ndi, ngati ayambe wodwala, kulimbikira zochitika yotsalira anaona monga matenda anathetsa ubongo.

Pseudomonas aeruginosa: chithandizo

Choyamba muyenera njira zasayansi kudziwa tilinazo tizilomboto kuti mankhwala. Chithandizo cha Pseudomonas aeruginosa, monga ulamuliro, liyenela kuikidwa kwa angapo (osachepera awiri) antibayotiki. Mu pachimake, moyo pachiswe nthawi imene nthawi kuyembekezera zotsatira za mbewu si mankhwala mankhwala amene amakhala tcheru mabakiteriya, kwa mlingo pazipita. Zikuphatikizapo mankhwala a penicillin chachisanu ndi m'badwo chimodzi (amdinotsillin, pitratsillin, azlocillin). Nthawi zambiri pali ogwira ndi carbenicillin. Ntchito ndi cephalosporins - tsefzulodin, ceftazidime. Nthawi zambiri pamodzi aminoglycoside ndi. Komanso ntchito mtsempha wa ciprofloxacin. Atalandira zotsatira za kufesa, chiwembu cha mankhwala mwachindunji.

Pamene kusonkhezera, aakulu, sachedwa matenda kudziletsa kuchiritsa, amene amayamba ndi Pseudomonas aeruginosa, mankhwala si nthawi zonse zofunikira. Nthawi zambiri yokwanira perekani mankhwala amodzi. Posachedwapa, zochizira Pseudomonas bacteriophage chimagwiritsidwa ntchito madzi. Komabe, tiyenera kukumbukira kuti mu nkhani iyi m'pofunika kudziwa tilinazo tizilomboto kuti kukonzekera kwachilengedwenso.